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Wyszukujesz frazę "Shah, P." wg kryterium: Autor

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    Wyświetlanie 1-8 z 8
    Tytuł:
    Synthesis and antimicrobial activity of some new imidazolinone derivatives containing benzimidazole
    Autorzy:
    Mehta, P.
    Davadra, P.
    Shah, N.
    Joshi, H.
    Powiązania:
    https://bibliotekanauki.pl/articles/411949.pdf
    Data publikacji:
    2014
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    benzimidazole
    imidazolinone
    antimicrobial activity
    Opis:
    In this study some new o-benzimidazol-2'-yl-benzamido-p'-benzamido-2-phenyl-4-substituted phenyl-5-oxo-Imidazolines 3a-3j were synthesized. To synthesized target molecules we used various substituted oxazolone derivatives, synthesized from substituted benzaldehyde with hippuric acid. Substituted oxazolones 2a-2j were reacted with carbohydrazide derivative of benzimidazole 1 in presence of pyridine as base to obtained substituted imidazolinone derivatives. All synthesized compounds were characterized by IR, 1H NMR, elemental analysis and further supported by mass spectroscopy. All synthesized compounds were screened for their antimicrobial activity against gram positive and gram negative bacteria which showed moderate to good activity. All compounds showing good to moderate active against fungal strain as compare to standard drug.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2014, 10; 74-80
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    A rapid, convient and diversified-multicomponent synthesis and characterization of pyrano[2,3-b]indoles
    Autorzy:
    Ghodasara, H. B.
    Singala, P. M.
    Shah, V. H.
    Powiązania:
    https://bibliotekanauki.pl/articles/412134.pdf
    Data publikacji:
    2014
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    1,3-bifunctional synthon
    Pyrano[2,3-b]indoles
    multi component reaction
    non-chromatographic metod
    Opis:
    A series of pyrano[2,3-b]indoles, was efficiently synthesized via one-pot, multi component reaction (MCRs) of 1,3-bifunctional synthon(malononitrile/ethylcyano acetate), aromatic aldehydes and oxiindole in the presence of various basic catalyst. The key advantages of this process are high yields, shorter reaction times, easy work-up, and purification of products by non-chromatographic method.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2014, 7; 69-76
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Novel s-Triazinyl Schiff Base/Chalcone Congeners: Rational, Synthesis, Antimicrobial and Anti-TB Evaluation
    Autorzy:
    Lakum, H. P.
    Shah, D. R.
    Chikhalia, K. H.
    Powiązania:
    https://bibliotekanauki.pl/articles/412603.pdf
    Data publikacji:
    2014
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    antimicrobial
    Anti-TB
    s-Triazine
    Schiff base
    Chalcone
    Opis:
    The occurrence of Multi Drug Resistant (MDR) infectious microbial strains has been increased upto alarming level which affects the public health worldwide. To cure this problem, a library of s-triazinyl derivatives comprising schiff base or chalcone motif have been rationalized, synthesized and screened for their in vitro antibacterial activity against five bacterial strains (Staphylococcus aureus MTCC 96, Bacillus subtilis MTCC 441, Escherichia coli MTCC 739, Pseudomonas aeruginosa MTCC 741 and Klebsiella pneumoniae MTCC 109) and four fungal strains (Aspergillus niger MTCC 282, Aspergillus fumigates MTCC 343, Aspergillus clavatus MTCC 1323, Candida albicans MTCC 183) using broth dilution technique. All the newly synthesized scaffolds were further evaluated for their in vitro anti-TB efficacy against the tubercular strain (Mycobacterium tuberculosis H37Rv) using Lowenstein-Jensen MIC method. All the derivatives were well characterized by IR, 1H NMR, 13C NMR, elemental analysis as well as mass spectroscopy.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2014, 19, 1; 56-73
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Synthesis and in vitro antimicrobial evaluation of amine substituted s-triazine based thiazolidinone/chalcone hybrids
    Autorzy:
    Shah, D. R.
    Lakum, H. P.
    Chikhalia, K. H.
    Powiązania:
    https://bibliotekanauki.pl/articles/412622.pdf
    Data publikacji:
    2014
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Antibacterial
    Antifungal
    Chalcone
    s-Triazine
    4-thiazolidinone
    Opis:
    In an attempt to control multidrug resistant dilemma, a library of s-triazine based on two novel series of thiazolidinone (4a-e) and chalcone (7a-e) derivatives were designed and synthesized with simple and efficient etiquette. The newly synthesized compounds were studied for efficacy against several bacteria (Staphylococcus Aureus, Bacillus Cereus, Pseudomonas Aeruginosa, Klebsiella Pneumoniae,) and fungi (Candida Albicans, Aspergillus Clavatus) using the broth dilution technique. Compound 7d was the best bioactive desired antibacterial analogue with less MIC value against different tested strains. Results of bioassay study revealed the future hope of the potent drug-candidate based on s-triazine scaffold. All the final synthesized compounds were characterized by IR, 1 H NMR, 13 C NMR, mass and elemental analysis.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2014, 17, 2; 207-219
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Synthesis and characterization of some new Schiff bases of 2-oxonaphtho[2,1-b][1,4]oxazine
    Autorzy:
    Chovatiya, P.
    Mehta, C.
    Senjani, H.
    Shah, A.
    Joshi, H. S.
    Powiązania:
    https://bibliotekanauki.pl/articles/411737.pdf
    Data publikacji:
    2014
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    2-Oxonaphtho[2,1-b][1,4]oxazine
    Schiff base
    Opis:
    The literature review reveal that [1,4]-oxazine derivatives represent one of the most active classes of compounds possessing wide spectrum of biodynamic activities and use as potent therapeutic agents. In the present work, a series of Schiff base of 2-(2,3-dihydro-2-oxonaphtho[2,1-b][1,4]oxazin-1-yl)acetohydrazide, 5a-5j has been synthesized using 1-aminonaphthalen-2-ol. Various aromatic aldehyde were react with carbohydrazide 4 in the presence of acid to produce the 2-oxonaphtho[2,1-b][1,4]oxazin Schiff base derivatives with good yields. All synthesized compounds were characterized by IR, NMR and Mass spectrometry analysis.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2014, 12; 26-30
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Synthesis, Characterization and Biological evaluation of some newer 5-[6-chloro/fluoro/nitro-2-(p-chloro/ fluoro/ methyl phenyl)-quinolin-4-yl]-1,3,4-oxadiazole-2-thiols
    Autorzy:
    Faldu, V. J.
    Talpara, P. K.
    Bhuva, N. H.
    Vachharajani, P. R.
    Shah, V. H.
    Powiązania:
    https://bibliotekanauki.pl/articles/412197.pdf
    Data publikacji:
    2014
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Quinolines
    1,3,4-oxadiazole-2-thiols
    therapeutic agents
    antimicrobial assai
    Opis:
    Recent study shows that quinolines represent one of the most active classes of compounds possesses wide spectrum biodynamic activities and use as potent therapeutic agents. In present research work, 5-[6-chloro/fluoro/nitro-2-(p-chloro/fluoro/methyl phenyl)-quinolin-4-yl]-1,3,4-oxadiazole-2-thiols have been synthesized by condensation of substituted quinoline-4-carbohydrazides and mixture of carbon disulphide and potassium hydroxide. All of these compounds were screened for their in vitroanti microbial assay against gram (+ve), gram (-ve) bacteria and fungi activity compared with standard drugs viz., Ampicilin, Chloramphenicol, Ciprofloxacin, Norfloxacin, Griseofulvin and Nystatin at different concentrations.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2014, 6; 26-32
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Synthesis, Characterization and Biological evaluation of 6-substituted-2-(substituted-phenyl)-quinoline derivatives bearing 4-amino-1,2,4-triazole-3-thiol ring at C-4 position
    Autorzy:
    Vaghasiya, R. G.
    Ghodasara, H. B.
    Vachharajani, P. R.
    Shah, V. H.
    Powiązania:
    https://bibliotekanauki.pl/articles/412211.pdf
    Data publikacji:
    2014
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Quinoline, 4-amino-1,2,4-triazole-3-thiol
    therapeutic agents
    antimicrobial assai
    Opis:
    Quinoline derivatives represent one of the most active classes of compounds possesses wide spectrum biodynamic activities and use as potent therapeutic agents. In this research work, a synthesis, characterization and biological evaluation of 6-substituted-2-(substituted-phenyl)-quinoline derivatives bearing 4-amino-1,2,4-triazole-3-thiol ring at C-4 position is described. The synthesis of quinoline derivatives is carried out by the reaction of substituted quinoline-4-carbohydrazides with a mixture of carbon disulphide and potassium hydroxide which further react with hydrazine hydrate to give final compounds. All of these compounds were screened for their in vitro antimicrobial assay against gram (+ve), gram (-ve) bacteria and fungi activity compared with standard drugs viz., Ampicilin, Chloramphenicol, Ciprofloxacin, Norfloxacin, Griseofulvin and Nystatin at different concentrations.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2014, 8; 30-37
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Synthesis of novel 2-mercapto-4-(p-aminophenyl sulphonylamino)-6-(aryl)-pyrimidine-5-carboxamide derivatives via the Biginelli reaction
    Autorzy:
    Bhuva, N. H.
    Gothalia, V. K.
    Singala, P. M.
    Talpara, P. K.
    Faldu, V. J.
    Shah, V. H.
    Powiązania:
    https://bibliotekanauki.pl/articles/412069.pdf
    Data publikacji:
    2014
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    2-mercapto-4-(p-aminophenylsulphonylamino)-6-(aryl)-pyrimidine-5-carboxamide
    Biginelli condensation
    Opis:
    Series of 2-mercapto-4-(p-aminophenylsulphonylamino)-6-(aryl)-pyrimidine-5-carboxamide Aa-h were synthesized via the biginelli condensation. 2-mercapto-4-amino-6-(aryl)-pyrimidine-5-carboxamide react with p-acetamidophenylsulphonylchloride in the presence of pyridine 2 to form 2-mercapto-4-(p-acetamidophenylsulphonylamino)-6-(aryl)-pyrimidine-5-carboxamide 3. It was treated with diluted HCl under reflux afforded 2-mercapto-4-(p-aminophenylsulphonylamino)-6-(aryl)-pyrimidine-5-carboxamide A a-h. The newly synthesized compounds were characterized by elemental analyses, infrared (IR), 1H NMR and 13 C NMR spectroscopic investigation.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2014, 17, 2; 168-173
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-8 z 8

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