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    Wyświetlanie 1-4 z 4
    Tytuł:
    Determination of kinetic parameters of decomposition of tetrahydropyrimidine derivatives
    Autorzy:
    Bhesaniya, K.
    Patel, A.
    Baluja, S.
    Powiązania:
    https://bibliotekanauki.pl/articles/411745.pdf
    Data publikacji:
    2013
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    tetrahydropyrimidine derivative
    TGA
    DSC
    kinetic parameter
    Opis:
    Some new tetrahydropyrimidine derivatives have been synthesized and their structural determination was done by IR, NMR and mass spectral data. Thermal analysis of these synthesized dihydropyrimidinthiones has been carried out by TGA and DSC techniques. From the thermograms, various kinetic parameters such as order of degradation (n), energy of activation (E), frequency factor (A) and entropy change (ΔS) have been evaluated. Further, thermal stability of tetrahydropyrimidine have been determined which is found to depend on the type of substituent present in the compounds.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2013, 13; 23-32
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Sustain release Formulation and Evaluation of Ofloxacin floating delivery system
    Autorzy:
    Patel, A. J.
    Naik, D. R.
    Raval, J. R.
    Powiązania:
    https://bibliotekanauki.pl/articles/412207.pdf
    Data publikacji:
    2014
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    ofloxacin
    ethyl cellulose
    xanthum gum
    floating drug delivery System
    controlled release
    Opis:
    Floating tablets has been accepted as a process to achieve controlled drug delivery by prolonging the residence time of the dosage form at the site of absorption, thereby improving and enhancing the bioavailability of drug. The objective of present study outlines the development and characterization the floating drug delivery system of Ofloxacin to enhance its bioavailability and therapeutic efficacy, using different grades of polymer along with effervescent agent sodium bicarbonate and citric acid. Ofloxacin is a synthetic chemotherapeutic second-generation antibiotic of the fluoroquinolone class. Different tablet formulations were formulated by wet granulation technique and were evaluated for physical parameters like Tablet Thickness, Hardness, % Friability, Weight variation, Content uniformity, In vitro buoyancy, Swelling index, In vitro dissolution study and drug release mechanisms. As the concentration of the polymer in the formulations increased the release of drug decreased. Hence it was considered as suitable candidate for formulation as floating drug delivery system. Different kinetic models were applied to drug release data in order to evaluate release mechanisms and kinetics. The optimized formula F4 showed better sustained drug release with good floating properties and fitted best to be Korsmeyer-Peppas model with R2 value of 0.9575. As the n value for the Korsmeyer- Peppas model was found be more than 0.5 it follows Non-Fickian diffusion mechanism. FTIR result showed that there is no drug excipients interaction.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2014, 12; 69-83
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Environmentally and Economically Feasibility Manufacturing Process of Potassium Nitrate for Small Scale Industries: A Review
    Autorzy:
    Joshi, C. S.
    Shukla, M. R.
    Patel, K.
    Joshi, J. S.
    Sahu, O.
    Powiązania:
    https://bibliotekanauki.pl/articles/411997.pdf
    Data publikacji:
    2015
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Chemical
    discharge
    ions
    Salts
    Waste
    Opis:
    Potassium Nitrate (PN) is of the basic need of chemical industry. With increase of demand in different production section of fertilizer, pharmaceutical, explosive, food industry etc, potassium nitrate the production becoming non economical to industry. The operating conditions and parameters are the main factors, which responsible for maximised the profits. The main aim of this study is to compared the production potassium nitrate in profitable as well as environmentally suitability way. From the literature different manufacturing process has been summarized for concluding this study.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2015, 41; 88-99
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    A convergent approach for the synthesis of new pyrazolyl bipyridinyl substituted coumarin derivatives as antimicrobials
    Autorzy:
    Bhila, V. G.
    Chovatiya, Y. L.
    Patel, C. V.
    Giri, R. R.
    Brahmbhatt, D. I.
    Powiązania:
    https://bibliotekanauki.pl/articles/411982.pdf
    Data publikacji:
    2015
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Coumarin
    Bipyridine
    Pyrazole
    Kröhnke’s reaction
    antimicrobial activity
    Opis:
    Some new 3-[3-(1-phenyl-3-aryl-1H-pyrazol-4-yl)acryloyl]coumarins 3a-f were synthesized (coumarin chalcones) by the condensation of various 3-acetyl coumarins 1 and appropriate 1-phenyl-3-aryl-1H-pyrazole-4-carbaldehyde 2. These coumarin chalcones 3a-f were then employed for the synthesis of pyrazolyl bipyridinyl substituted coumarins 7a-f, 8a-f, and 9a-f under Krohnke’s reaction condition. The characterization of all the synthesized compounds was carried out by elemental analysis, IR, 1H-NMR, 13C-NMR, DEPT-135 and mass spectral analysis. In addition to that, in vitro antimicrobial competency of the title compounds was assessed against selected pathogens. Compounds 3b, 3e, 7b, 8b, 8c and 9b exhibited excellent antimicrobial activity and said to be the most proficient members of the series.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2015, 40; 1-16
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-4 z 4

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