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    Wyświetlanie 1-7 z 7
    Tytuł:
    Participation of metallothionein and superoxide dismutase in the blood of smoking smelters
    Autorzy:
    Bizoń, Anna
    Milnerowicz, Halina
    Powiązania:
    https://bibliotekanauki.pl/articles/2178842.pdf
    Data publikacji:
    2014-05-17
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    Oxidative stress
    cigarette smoking
    occupational exposure
    antioxidants levels
    Opis:
    Objectives: Metallothionein (MT) and two forms of superoxide dismutase (SOD), which are dependent on zinc and copper ions, are involved in defense against the same superoxide anion radicals and are present in extra- and intracellular compartments. The aim of our study was to investigate MT concentration and Cu/Zn SOD activity in the plasma and erythrocyte lysate of the non-smoking and smoking smelters. Material and Methods: The investigations were performed in the blood of 300 male smelters and 100 non-exposed male subjects. We have measured zinc, copper, malondialdehyde (MDA) and MT concentrations as well as SOD activity. Results: We have observed an increase of Cu/Zn coefficient and decrease of Zn/Cu coefficient in the serum of smelters in comparison with the non-smoking control group. Concentration of MDA in the plasma of smelters was higher in comparison with its concentration in the non-smoking control group. The plasma and the erythrocyte lysate MT concentration increased significantly in the whole group of smelters as compared to the non-smoking control group. The mean value of MT concentration in plasma of the smoking smelters was above 2-fold higher than in the non-smoking control group. The activity of Cu/Zn SOD in plasma of the smoking and non-smoking smelters was decreased in comparison with the smoking and non-smoking control groups, respectively. The lowest activity of Cu/Zn SOD, about 2-3‑fold decreased in comparison with the smoking and non-smoking control groups, was detected in plasma of the smelters. An inverse relationship was observed in the erythrocyte lysate. The highest activity of Cu/Zn SOD was reported in the erythrocyte lysate of the smoking smelters and it was about 2-fold higher than in the non-smoking control group. Conclusions: In extracellular environment MT plays a crucial role in comparison with the SOD, while in the intracellular compartment Cu/Zn SOD and MT cooperate with each other.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2014, 27, 2; 326-334
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Cigarette smoking and mammographic breast density among Polish women
    Autorzy:
    Pepłońska, Beata
    Kalużny, Pawel
    Powiązania:
    https://bibliotekanauki.pl/articles/2093853.pdf
    Data publikacji:
    2021-12-13
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    breast cancer
    tobacco
    lifestyle
    cigarette smoking
    Polish women
    mammographic density
    Opis:
    ObjectivesHigh mammographic breast density (MBD) is one of the strongest breast cancer risk factors. The results of some epidemiological studies suggest that one of the lifestyle factors likely altering breast density is cigarette smoking. The aim of this study was to assess the association between active smoking, considering in detail the duration and intensity of smoking, and MBD among Polish women.Material and MethodsA cross-sectional study included 467 women aged 40–60 years who underwent screening mammography in Łódź, Poland. Volumetric mammographic density, fibroglandular tissue volume and non-fibroglandular tissue volume were determined based on the analysis of mammographic image (in the “for processing” format) using Volpara Imaging Software. Current and lifetime intensity of cigarette smoking was assessed based on the data from interviews. Linear and logistic regressions were fitted with estimated MBD parameters as the outcomes, and life-long smoking duration and intensity as the determinants, adjusted for major confounders.ResultsThe former smokers had a significantly lower volumetric mammographic density compared to the non-smokers in the crude analysis (p = 0.022). However, the associations became insignificant after adjustments for important confounding factors. The analyses adjusted for important confounders revealed an inverse statistically significant association between the number of pack-years and volumetric mammographic density among the current smokers (p = 0.048).ConclusionsThe observed result is consistent with the majority of previous studies that analyzed the associations between mammographic density and life-long smoking duration.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2021, 34, 6; 805-815
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Deteriorations of pulmonary function, elevated carbon monoxide levels and increased oxidative stress amongst water-pipe smokers
    Autorzy:
    Yalcin, Funda K.
    Er, Mukremin
    Hasanoglu, H. Canan
    Kilic, Hatice
    Senturk, Aysegul
    Karalezli, Aysegul
    Ergin, Merve
    Erel, Ozcan
    Powiązania:
    https://bibliotekanauki.pl/articles/2161884.pdf
    Data publikacji:
    2017-07-14
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    Oxidative stress
    carbon monoxide
    cigarette smoking
    pulmonary function tests
    antioxidant status
    water-pipe smoking
    Opis:
    Objectives A water pipe (hookah) is a tobacco smoking tool which is thought to be more harmless than a cigarette, and there are no adequate studies about its hazards to health. Water-pipe smoking is threatening health of the youth in the world today. The objective of this study has been to investigate the carbon monoxide (CO) levels in breath, examine the changes in pulmonary function tests (PFT) and to assess the change of the oxidative stress parameters in blood after smoking a water pipe. Material and Methods This study is a cross-sectional analytical study that has included 50 volunteers who smoke a water pipe and the control group of 50 volunteers who smoke neither a cigarette nor a water pipe. Carbon monoxide levels were measured in the breath and pulmonary function tests (PFTs) were performed before and after smoking a water pipe. Blood samples were taken from either the volunteer control group or water-pipe smokers group after smoking a water pipe for the purpose of evaluation of the parameters of oxidative stress. Results Carbon monoxide values were measured to be 8.08±7.4 ppm and 28.08±16.5 ppm before and after smoking a water pipe, respectively. This increment was found statistically significant. There were also significant reductions in PFTs after smoking a water pipe. Total oxidative status (TOS), total antioxidant status (TAS) and oxidative stress index (OSI) were found prominently higher after smoking a water pipe for the group of water-pipe smokers than for the control group. Conclusions This study has shown that water-pipe smoking leads to deterioration in pulmonary function and increases oxidative stress. To the best of our knowledge this study is the only one that has shown the effect of water-pipe smoking on oxidative stress. More studies must be planned to show the side effects of water-pipe habit and protective policies should be planned especially for young people in Europe. Int J Occup Med Environ Health 2017;30(5):731–742
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2017, 30, 5; 731-742
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Authors’ response (December 7, 2017) to the letter to the Editor concerning the paper “Trends in smoking among secondary school and high school students in Poland, 2009 and 2011”
    Autorzy:
    Wojtyła-Buciora, Paulina
    Stawińska-Witoszyńska, Barbara
    Żukiewicz-Sobczak, Wiola
    Wojtyła, Cezary
    Biliński, Piotr
    Urbaniak, Monika
    Wojtyła, Andrzej
    Marcinkowski, Jerzy T.
    Wojciechowska, Małgorzata
    Powiązania:
    https://bibliotekanauki.pl/articles/2160042.pdf
    Data publikacji:
    2018-07-04
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    health education
    cigarette smoking
    tobacco epidemiology
    smoking initiation
    secondary school students
    high school students
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2018, 31, 4; 541-542
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Trends in smoking among secondary school and high school students in Poland, 2009 and 2011
    Autorzy:
    Wojtyła-Buciora, Paulina
    Stawińska-Witoszyńska, Barbara
    Żukiewicz-Sobczak, Wiola
    Wojtyła, Cezary
    Biliński, Piotr
    Urbaniak, Monika
    Wojtyła, Andrzej
    Marcinkowski, Jerzy T.
    Wojciechowska, Małgorzata
    Powiązania:
    https://bibliotekanauki.pl/articles/2161891.pdf
    Data publikacji:
    2017-07-14
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    health education
    cigarette smoking
    high school students
    tobacco epidemiology
    smoking initation
    secondary school students
    Opis:
    Objectives To determine the age and the most common circumstances for smoking initiation along with smoking rates and to evaluate smoking trends for secondary and high school students in Poland during 2009 and 2011. Material and Methods In 2009, a pilot study was conducted in districts of Poland on high school students and their parents. For statistical analysis, correctly completed questionnaires from 999 students and 667 parents were qualified for use. After the pilot study, a nationwide study of secondary school students and their parents was also conducted in 2009. For statistical analysis, correctly completed questionnaires were used from 9360 students and 6951 from their parents. The research tool was a questionnaire developed by the Chief Sanitary Inspectorate. These studies were then compared to the nationwide research study from 2011. Questionnaires were obtained from a survey of 3548 students from secondary schools and 4423 of those from high schools. Results Smoking initiation usually begins at ages 12–15 years. Rates of secondary school student smoking at least once in their lifetime were about the same level in the surveyed years (2009 – 9%, 2011 – 11%), whereas rates of high school student smoking increased (2009 – 15%, 2011 – 24%). Moreover, 34% of secondary school student smoked less than once a week, whereas in 2009, only 8% of students had done so. For high school students, a 1/2 smoked every day; similar to 2009. Students usually smoked in parks, on streets or any other open space areas. Conclusions From analyzing the smoking trends over the survey period it can be concluded that the problem of smoking increases with respondent age. Int J Occup Med Environ Health 2017;30(5):763–773
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2017, 30, 5; 763-773
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Assessment of DNA damage using chromosomal aberrations assay in lymphocytes of waterpipe smokers
    Autorzy:
    Alsatari, Enas S.
    Azab, Mohammad
    Khabour, Omar F.
    Alzoubi, Karem H.
    Sadiq, May F.
    Powiązania:
    https://bibliotekanauki.pl/articles/2180083.pdf
    Data publikacji:
    2012-06-01
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    waterpipe
    smoking
    cigarette
    chromosomal aberrations
    Opis:
    Objectives: The aim of this study was to investigate the genotoxicity of waterpipe smoking in the lymphocytes of waterpipe smokers using chromosomal aberrations (CAs) assay. Materials and Methods: Fifty waterpipe smokers and 18 healthy nonsmokers volunteered to participate in the study. Additionally, 18 heavy cigarette smokers were recruited for comparison. Chromosomal aberrations (CAs) assay was used to evaluate DNA damage in the lymphocytes. Results: The results showed that similarly to cigarette smoking, waterpipe smoking significantly increased the frequencies of CAs (p < 0.01). In addition, the frequencies of CAs increased with more waterpipe use. Conclusions: Waterpipe smoking causes DNA damage to lymphocytes and the damage increases with more waterpipe use.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2012, 25, 3; 218-224
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    E-smoking: Emerging public health problem?
    Autorzy:
    Jankowski, Mateusz
    Brożek, Grzegorz
    Lawson, Joshua
    Skoczyński, Szymon
    Zejda, Jan E.
    Powiązania:
    https://bibliotekanauki.pl/articles/2161883.pdf
    Data publikacji:
    2017-05-08
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    smoking
    nicotine
    literature review
    e-cigarette
    electronic cigarette
    tobacco products
    Opis:
    E-cigarette use has become increasingly popular, especially among the young. Its long-term influence upon health is unknown. Aim of this review has been to present the current state of knowledge about the impact of e-cigarette use on health, with an emphasis on Central and Eastern Europe. During the preparation of this narrative review, the literature on e-cigarettes available within the network PubMed was retrieved and examined. In the final review, 64 research papers were included. We specifically assessed the construction and operation of the e-cigarette as well as the chemical composition of the e-liquid; the impact that vapor arising from the use of e-cigarette explored in experimental models in vitro; and short-term effects of use of e-cigarettes on users’ health. Among the substances inhaled by the e-smoker, there are several harmful products, such as: formaldehyde, acetaldehyde, acroleine, propanal, nicotine, acetone, o-methyl-benzaldehyde, carcinogenic nitrosamines. Results from experimental animal studies indicate the negative impact of e-cigarette exposure on test models, such as ascytotoxicity, oxidative stress, inflammation, airway hyper reactivity, airway remodeling, mucin production, apoptosis, and emphysematous changes. The short-term impact of e-cigarettes on human health has been studied mostly in experimental setting. Available evidence shows that the use of e-cigarettes may result in acute lung function responses (e.g., increase in impedance, peripheral airway flow resistance) and induce oxidative stress. Based on the current available evidence, e-cigarette use is associated with harmful biologic responses, although it may be less harmful than traditional cigarettes. Int J Occup Med Environ Health 2017;30(3):329–344
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2017, 30, 3; 329-344
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-7 z 7

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