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Wyświetlanie 1-4 z 4
Tytuł:
Polish mother and child cohort study (REPRO_PL) — Methodology of follow-up of the children
Autorzy:
Polańska, Kinga
Hanke, Wojciech
Jurewicz, Joanna
Sobala, Wojciech
Madsen, Christian
Nafstad, Per
Magnus, Per
Powiązania:
https://bibliotekanauki.pl/articles/2185377.pdf
Data publikacji:
2011-12-01
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
birth cohort
follow-up of children
child’s health
neurodevelopment
Opis:
Background: A prospective cohort study design gives the opportunity for identifi cation, update of different exposures and their verifi cation by biomarker measurements. The aim of The Polish Mother and Child Cohort Study (REPRO_PL) is to evaluate the impact of exposure to different environmental factors during pregnancy and, after birth, on the pregnancy outcome, children’s health and neurodevelopment. Materials and Methods: REPRO_PL cohort was established in 2007. From the cohort of 1300 mother-child pairs, 300 children are followed-up until they are two years old to asses the exposure, health status and neurodevelopment. Children are examined twice: at one and two years of age by a pediatrician and a psychologist/child development specialist. During each visit, detailed questionnaire is conducted with the mothers and supplemented with the information from the medical charts to have appropriate recognition of the child’s health and development. Additionally, the current health status of the child is checked and his/her biometry is performed. A urine sample is collected from each child for the verifi cation of environmental tobacco smoke (ETS) and polycyclic aromatic hydrocarbons (PAH) exposure. Some children have a blood sample collected for the assessment of the lead and cadmium levels. Child’s neurodevelopment is assessed based on Bayley Scales for Infant and Toddler Development (Bayley-III). Results and Conclusions: The results of the study will become available within the next few years and will help to determine the impact of the environmental exposures on children’s health and neurodevelopment. REPRO_PL cohort is a middle-sized cohort, very much focused on specific research questions with the potential for future extension and cooperation.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2011, 24, 4; 391-398
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of environmental phthalate exposure on pregnancy duration and birth outcomes
Autorzy:
Polańska, Kinga
Ligocka, Danuta
Sobala, Wojciech
Hanke, Wojciech
Powiązania:
https://bibliotekanauki.pl/articles/2177431.pdf
Data publikacji:
2016-06-16
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
prenatal exposure
gestational age
cohort study
phthalates
urinary metabolites
birth outcomes
Opis:
Objectives The objective of this study was to evaluate the impact of phthalate exposure on pregnancy duration and birth outcomes based on the Polish Mother and Child Cohort (REPRO_PL). Material and Methods Phthalate exposure was determined by measuring 11 phthalate metabolites (mono-ethyl phthalate (MEP), mono-iso-butyl phthalate (MiBP), mono-n-butyl phthalate (MnBP), 3OH-mono-n-butyl phthalate (OH-MnBP), mono-benzyl phthalate (MBzP), mono‑ (2-ethylhexyl) phthalate (MEHP), mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), mono-(2-ethyl-5-oxohexyl) phthalate (MEOHP), mono-hydroxy-iso-nonyl phthalate (MHiNP), mono-oxo-iso-nonyl phthalate (MOiNP), and mono-n-octyl phthalate (MOP)) in the urine collected from 165 mothers during the third trimester of pregnancy by high performance liquid chromatography with tandem mass spectrometry (HPLC-MS/MS). The following measures at birth were considered: gestational age, birth weight, length as well as head and chest circumference. Results Pregnancy duration was inversely associated with natural log concentrations (μg/g creatinine) of MEP (standardized regression coefficient (β) = –0.2, p = 0.04) after adjustment for a variety of confounders. Significant impact of MOiNP on head circumference (β = –0.1, p = 0.05) was also observed. Conclusions The study findings add further support to the hypothesis that phthalate exposure may be associated with shorter pregnancy duration and a decreased head circumference, and underscore importance of public health interventions to reduce that exposure.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2016, 29, 4; 683-697
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland
Autorzy:
Baczyńska-Strzecha, Marta
Kalinka, Jarosław
Powiązania:
https://bibliotekanauki.pl/articles/2161845.pdf
Data publikacji:
2017-10-06
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
pregnancy
vitamin D
preterm delivery
vitamin D deficiency
preterm birth
preterm labor
Opis:
Objectives Aim of this project is determination of the correlation between the level of vitamin D in blood serum and duration of pregnancy in population in central Poland. Material and Methods 25-Hydroxyvitamin D (25(OH)D) level was determined in blood serum, using enzyme-linked immunosorbent assay (ELISA). Standardized history of each patient was recorded. The history included: general medical history, data regarding the course of pregnancy and information about health-related behavior that could influence vitamin D concentration. Two hundred-and-one Caucasian women at childbirth were qualified into the study. The study group was divided into 2 parts: 100 patients who had a spontaneous premature birth and 101 patients who had birth at full term. Results Vitamin D deficiency (< 30 ng/ml) was very common for both groups (69.6% of patients in the premature group and 72% – in the control group). Patients who had a premature birth had severe vitamin D deficiency (less than 10 ng/ml) more often than in the control group (34% vs. 14.2%, p = 0.001). Severe vitamin D deficiency increased the risk of premature birth but the association was not statistically significant in the multivariate regression model (odds ratio (OR) = 2.47, 95% confidence interval (CI): 0.86–7.15, p = 0.094). Conclusions Severe vitamin D deficiency (< 10 ng/ml) may be the factor increasing the risk of preterm birth. Int J Occup Med Environ Health 2017;30(6):933–941
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2017, 30, 6; 933-941
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Polish Mother and Child Cohort Study (REPRO_PL) – Methodology of the follow-up of the children at the age of 7
Autorzy:
Polańska, Kinga
Hanke, Wojciech
Król, Anna
Potocka, Adrianna
Waszkowska, Małgorzata
Jacukowicz, Aleksandra
Gromadzińska, Jolanta
Wąsowicz, Wojciech
Jerzyńska, Joanna
Stelmach, Włodzimierz
Stelmach, Iwona
Powiązania:
https://bibliotekanauki.pl/articles/2168369.pdf
Data publikacji:
2016-11-18
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
lifestyle
exposure
neurodevelopment
birth cohort
follow-up of children
child’s health
Opis:
Effects of environmental exposures in utero and in the first years of life on early life health and development is a growing research area with major public health implications. The main aim of this work has been to provide an overview of the next step of the Polish Mother and Child Cohort Study (REPRO_PL) covering exposure, health and neurodevelopment assessments of children at 7 years of age. Details regarding methodology of the follow-up of the children are crucial for cross-cohort collaboration and a full understanding of the future research questions. Phase III of the REPRO_PL cohort covers a follow-up of 900 children at the age of 7 years old. The questionnaire filled in by the mothers is composed of: socio-demographic, child exposure and home environment information, nutritional status and health data. In the case of 400 children, environmental (including collection of urine, saliva and buccal cells), health status and psychomotor assessments are performed. Health and development check consists of physical measurements, child health status assessment (including lung function tests, skin prick testing, an interview/examination by an allergist) and psychomotor development tests (the Strength and Difficulties Questionnaire and the Intelligence and Development Scales). The results of the study will become available within the next few years. Extension of the REPRO_PL cohort with examinations of children at the age of 7 years old may provide a better understanding of the relationship between environmental and lifestyle-related factors and children’s health and neurodevelopment; and may further strengthen scientific base for policies and interventions promoting healthy lifestyle. Int J Occup Med Environ Health 2016;29(6):883-893
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2016, 29, 6; 883-893
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-4 z 4

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