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Wyświetlanie 1-3 z 3
Tytuł:
Utilizing the metabolic syndrome component count in workers’ health surveillance: An example of day-time vs. day-night rotating shift workers
Autorzy:
Lin, Yu Cheng
Hsieh, I-Chun
Chen, Pau-Chung
Powiązania:
https://bibliotekanauki.pl/articles/2177229.pdf
Data publikacji:
2015-07-01
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
metabolic syndrome
day-and-night rotating shift work
occupational health
physical examination
Opis:
Objectives To establish a practical method for assessing the general metabolic health conditions among different employee groups, this study utilized the total count of metabolic syndrome (MetS) elements as a parameter, and performed a retrospective analysis comparing changes of MetS component count (MSC) of 5 years among day-time work (DW) and day-andnight rotating shift work (RSW) employees. Material and Methods The data of personal histories, physical examinations, blood tests, abdominal sonographic examinations and occupational records were collected from a cohort of workers in an electronics manufacturing company. We first defined the arithmetic mean value of MSC as MSC density (MSCD) for the employee group; then we compared the changes of MSCD over 5 years between DW and RSW workers. Occupational, personal and health records were analyzed for the 1077 workers with an initial mean age of 32.4 years (standard deviation (SD): 6.2 years), including 565 RSW workers (52%). Results The initial MSCDs were 1.26 and 1.12 (p = 0.06) for DW and RSW workers, respectively; after 5 years, the increments of MSCD for DW and RSW workers were 0.10 and 0.39, respectively (p < 0.01). By performing multivariate logistic regression analyses, and comparing with DW co-workers, final results indicated that the workers exposed to RSW have 1.7-fold increased risk of elevated MSCD (95% confidence interval (CI): 1.28–2.25, p < 0.01); and are 38% less likely (adjusted rate ratio (aRR) 0.62, 95% CI: 0.45–0.86, p < 0.01) to attain decreased MSCD. Conclusions These observations demonstrate that changes of MSCD are significantly different between DW and RSW workers, and are increasingly associated with RSW exposure. In conclusion, MSCD can represent the general metabolic health conditions of a given employee group; MSC, MSCD and their transitional changes can be applied as simple and standardized tools for monitoring metabolic health risk profiles when managing employee health, at both the individual and company levels.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2015, 28, 4; 675-688
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effects of benzo(a)pyrene exposure on the ATPase activity and calcium concentration in the hippocampus of neonatal rats
Autorzy:
Yang, Kai
Chen, Chengzhi
Cheng, Shuqun
Cao, Xianqing
Tu, Baijie
Powiązania:
https://bibliotekanauki.pl/articles/2161850.pdf
Data publikacji:
2017-03-30
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
hippocampus
neurodevelopment
ATPase activity
Ca2+ concentration
neonatal rats
Benzo(a)pyrene
Opis:
Objectives To investigate whether postnatal benzo(a)pyrene (B(a)P) exposure caused the impairments on the process of neurodevelopment and the alteration in the calcium medium in the neonatal rats. Material and Methods Eighty neonatal Sprague Dawley (SD) rats were randomly divided into 5 groups (untreated control group, vehicle group, 0.02 mg/kg, 0.2 mg/kg and 2 mg/kg B(a)P-exposed group). Rats were treated with B(a)P by the intragastric administration from postnatal day (PND) 4 to 25. Morris water maze (MWM) was employed to observe the spatial memory of rats. The activity of calcium adenosine triphosphatase (Ca2+-ATPase), sodium-potassium adenosine triphosphatase (Na+-K+-ATPase) and calcium-magnesium adenosine triphosphatase (Ca2+-Mg2+-ATPase) in the hippocampus were detected by commercial kits. Fura-2 pentakis(acetoxymethyl) (Fura-2/AM) probe and reactive oxygen species (ROS) reagent kit were used for measuring the concentration of Ca2+ and ROS in the hippocampus synapse, respectively. Results Rats exposed to B(a)P resulted in the deficits in the spatial memory manifested by the increased escape latency and decreased number of crossing platform and time spent in target quadrant in comparison with the control groups. Benzo(a)pyrene exposure caused the significant decrease in the ATPase activity in the hippocampus and caused Ca2+ overload in the synaptic, besides, the ROS concentration increased significantly which may further induce neurobehavioral impairment of the neonatal rats. Conclusions Our findings suggest that postnatal B(a)P exposure may cause the neurobehavioral impairments in the neonatal rats, which were mediated by the decreased ATPase activity and elevated Ca2+ concentration. Int J Occup Med Environ Health 2017;30(2):203–211
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2017, 30, 2; 203-211
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The relationship between manganism and the workplace environment in China
Autorzy:
Wang, Yongyi
Xue, Jian
Cheng, Shuqun
Ding, Yubin
He, Junlin
Liu, Xueqing
Chen, Xuemei
Wang, Yingxiong
Feng, Xiangyu
Xia, Yinyin
Powiązania:
https://bibliotekanauki.pl/articles/2180079.pdf
Data publikacji:
2012-09-01
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
manganese
occupational exposure
welding
mining
occupational intoxication
chronic manganism
Opis:
Manganese is a trace element and a cofactor of many enzymes, so it is essential for physiologic functioning, but it is also a neurotoxin at high doses. Manganism is most often caused by occupational exposure. It is manifested by a myriad of signs and symptoms ranging from the neurasthenia syndrome, such as headache and dizziness, to the Parkinson-like syndrome, depending on the blood manganese levels as well as the duration of exposure. We are reporting a case of manganism using both clinical and occupational hygiene investigation methods. The patient presented the neurasthenia syndrome accompanied by hypertonicity of arm muscles and was diagnosed to have mild chronic manganism. Finally, the patient was discharged from the hospital after the treatment had improved her condition. In China, there are many chronic manga nese cases, partly due to a rapid industrial development with great use of Mn and the low self-protection awareness among the workers and the factories management that cannot catch up with the speed of the economical development. Therefore, factories are responsible for improving the conditions at the workplace.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2012, 25, 4; 501-505
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-3 z 3

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