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    Tytuł:
    The importance of obesity and carbohydrate metabolism disorders on the course of gastroesophageal reflux disease – a pilot study
    Autorzy:
    Pardak, Piotr
    Filip, Rafał
    Krzaczek, Maciej
    Powiązania:
    https://bibliotekanauki.pl/articles/2203254.pdf
    Data publikacji:
    2022-05-31
    Wydawca:
    Gdański Uniwersytet Medyczny
    Tematy:
    obesity
    gastroesophageal reflux disease
    diabetes mellitus
    Opis:
    BackgroundCarbohydrate metabolism disorders, obesity and a severe course of gastroesophageal reflux correlate with more frequent development of esophageal complications. The aim of this study was to assess the influence of obesity and carbohydrate disorders on the characteristics of gastroesophageal reflux disease (GERD).Material and methodsThe study included 58 patients with excess weight. Anthropometric parameters (including the body mass index, BMI), data regarding GERD (severity of symptoms, gastroscopy and esophageal pH monitoring results) were included in the study. Correlations between obesity and GERD parameters were analyzed. Subjects were divided into a diabetic and a control group and the severity of GERD was compared.ResultsGERD was diagnosed in 40 patients and occurred more frequently in the obese group (73%) than in the overweight group (57%). Increased GERD severity was associated with increased BMI only for postprandial parameters. GERD was diagnosed in most of the group with carbohydrate disorders (78% vs 63% in the non-diabetic group). No differences in the severity of GERD were observed between groups depending on carbohydrate disorders.ConclusionsIn our study, GERD was common in obesity and in diabetic disorders. Increased severity of postprandial reflux was associated with an increased BMI. Diabetic disorders were not associated with more severe GERD.
    Źródło:
    European Journal of Translational and Clinical Medicine; 2022, 5, 1; 17-26
    2657-3148
    2657-3156
    Pojawia się w:
    European Journal of Translational and Clinical Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Acute cholecystitis in patients with diabetes mellitus - systematic review
    Autorzy:
    Łącka, Monika
    Spychalski, Piotr
    Dobrzycka, Małgorzata
    Rostkowska, Olga
    Kobiela, Jarosław
    Powiązania:
    https://bibliotekanauki.pl/articles/895729.pdf
    Data publikacji:
    2020-01-09
    Wydawca:
    Gdański Uniwersytet Medyczny
    Tematy:
    complications
    Diabetes Mellitus
    Cholecystitis
    course of hospitalization
    Opis:
    Introduction: According to the WHO, an estimated 422 million people are suffering from diabetes worldwide. Among them, the incidence of cholelithiasis is higher than in the healthy population. The aim of this literature review was to summarize the available evidence about acute cholecystitis in patients with diabetes. Materials and methods: This study adhered to the PRISMA guidelines. The course of hospitalization of patients with and without diabetes who underwent cholecystectomy due to acute cholecystitis was compared. Following information was abstracted from original studies: general study information, patient characteristics, complications, and recommendations for patients with diabetes. Results: Initial search provided 1632 results. After full text assessment, 40 studies met the inclusions criteria. Operative and postoperative complication rates were significantly higher among the diabetic patients. Diabetes is a risk factor for conversion from laparoscopic to open cholecystectomy method. The authors' opinions on elective surgery before the onset of acute cholecystitis symptoms are divided. Conclusions: Diabetic patients are at greater risk of developing complications. An individualized screening and treatment approach, as well as proper preparation of the diabetic patient for an elective cholecystectomy could have a positive effect on the outcome. However, the low quality of the data from the systematic review does not allow for meta-analysis, which is why we cannot draw strong conclusions.
    Źródło:
    European Journal of Translational and Clinical Medicine; 2019, 2, 2; 71-79
    2657-3148
    2657-3156
    Pojawia się w:
    European Journal of Translational and Clinical Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Endocrine disorders in patients with hereditary hemochromatosis
    Autorzy:
    Banaszkiewicz, Katarzyna
    Sikorska, Katarzyna
    Sworczak, Krzysztof
    Powiązania:
    https://bibliotekanauki.pl/articles/895739.pdf
    Data publikacji:
    2019-02-05
    Wydawca:
    Gdański Uniwersytet Medyczny
    Tematy:
    Diabetes Mellitus
    Osteoporosis
    endocrinology
    iron overload
    hemochromatosis
    Opis:
    Hereditary hemochromatosis (HH) is a rare genetic disorder, developing secondary to the accumulation of iron in tissues, which may lead to multiple organ failure. If untreated, it may result in liver cirrhosis or cardiomyopathy. The damage to the pancreas and the anterior pituitary, on the other hand, leads to a decreased production and secretion of hormones that are essential to life. Common symptoms of HH, that are distressing for patients, include joint pain, particularly involving hands and wrists, as well as the chronic fatigue syndrome. Iron overload affects the skeletal system, leading to osteoporosis. The pathological accumulation of iron in the anterior pituitary impairs the gonadotropin synthesis, resulting in reduced serum levels of testosterone in men and estrogens in women. This, however, contributes to lower bone mass. In vivo tests have also revealed that abnormal iron accumulation is related to an increased activity and number of osteoclasts, as well as the influence on the differentiation and activity of osteoblast-lineage cells. Based on a systematic review of literature, hereditary hemochromatosis (HH) will be presented as a chronic disease, affecting most of the endocrine glands.
    Źródło:
    European Journal of Translational and Clinical Medicine; 2018, 1, 2; 72-76
    2657-3148
    2657-3156
    Pojawia się w:
    European Journal of Translational and Clinical Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Physical activity in type 2 diabetes mellitus: a review
    Autorzy:
    Burooj, Ahmed
    Powiązania:
    https://bibliotekanauki.pl/articles/33777868.pdf
    Data publikacji:
    2024-04-10
    Wydawca:
    Gdański Uniwersytet Medyczny
    Tematy:
    T2DM
    Exercise
    Diabetes
    Diabetes Mellitus
    Physical Activity
    Opis:
    Introduction This literature review explores the role of physical activity (PA) in managing and preventing type 2 diabetes mellitus (T2DM), synthesizing the latest guidelines for all T2DM patients. Following PRISMA guidelines, it identifies specific areas for further research. Material and Methods Indexing services (PubMed and Scopus) were used to identify relevant studies, emphasizing original research, review articles, and updated institutional guidelines spanning 2017-2023. The following keywords were used: diabetes, physical activity, type 2 diabetes mellitus, PA, and exercise. Proposal and opinion articles, non-English papers (or those lacking full-text translation), studies involving non-human subjects, pediatric populations or with skewed gender distribution were excluded. Results PA improves quality of life, BMI, glycemic control and well-being. Effects vary by activity domain, such as work or leisure time. Recommendations suggest 60 daily minutes of exercise for children, 150 weekly minutes of moderate intensity exercise for adults, and screening for adverse events. A “sit-less” approach is proposed for those unable to maintain regular activity, with glycemic monitoring for those with variability. Conclusions PA is crucial in T2DM management. Conflicting findings regarding glycemic control warrant further investigation to ascertain causes, whether related to bias or other factors.
    Źródło:
    European Journal of Translational and Clinical Medicine; 2024, 7, 1; 97-105
    2657-3148
    2657-3156
    Pojawia się w:
    European Journal of Translational and Clinical Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Analysis of diabetes-related complications and the cost of diabetes in Poland. The methodology and the research sample used in Economedica DM-PL Survey
    Autorzy:
    Bogusławski, Stefan
    Wojciechowska, Agata
    Smaga, Anna
    Strojek, Krzysztof
    Wróbel, Katarzyna
    Wojtyniak, Bogdan
    Juszczyk, Grzegorz
    Czech, Marcin
    Zdrojewski, Tomasz
    Powiązania:
    https://bibliotekanauki.pl/articles/2203241.pdf
    Data publikacji:
    2023-06-07
    Wydawca:
    Gdański Uniwersytet Medyczny
    Tematy:
    diabetes mellitus
    prevalence
    cost of illness
    research design
    Opis:
    Background: Knowledge about diabetes mellitus (DM)-related complications, the direct and indirect costs incur red by patients with DM is still insufficient in Poland. Economedica DM-PL (Economedica) survey was a cross-sectional observational study that aimed to assess these issues. Material and methods: The survey was carried out in 2016 on a representative sample of 2032 diabetic patients recruited by 195 general practioners (GP) and 48 diabetologists (D) randomly selected from the national registry of physicians. Each GP and D recruited 8 to 10 patients with DM according to the specified protocol. The study included 1938 medical questionnaires (comple ted by the GPs and Ds), 1938 questionnaires about costs (completed by the patients) and 1532 treatment adherence questionnaires. Results: The Economedica survey provided new insights into DM epidemiological and cost data. 70% of patients with type-1 DM were diagnosed with the disease before the age of 40. For 76% patients with type-2 DM, it was diagnosed aeftr the age of 50. The average monthly out-of-pocket medical costs for DM patients in 2016 reached 66.2 EUR, while their non-medical costs were 36.8 EUR. Conclusions: The methodology applied in our study proved useful for providing new dimensions of DM epidemiological and cost data in Poland.
    Źródło:
    European Journal of Translational and Clinical Medicine; 2023, 6, 1; 31-40
    2657-3148
    2657-3156
    Pojawia się w:
    European Journal of Translational and Clinical Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-5 z 5

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