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Tytuł:
Anticancer properties of Viburnum
Autorzy:
Stępień, Agnieszka
Aebisher, David
Bartusik-Aebisher, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/454949.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
antitumor activity
Viburnum species
cytotoxic activity
Opis:
Aim. The aim of this paper is to provide an overview of the anticancer properties of different species of Viburnum. Materials and methods. Forty nine papers that discuss the medicinal history and current research of Viburnum species as phytotherapeutic agent were used for this discussion. Literature analysis. The results of scientific research conducted in vitro indicate that the compounds present in the extracts of Viburnum significantly affect the development of cancer cells such as leukemia, cervical cancer, breast, colon, lung, skin and stomach. This indicates that they may be used as a therapeutic agent to support oncological therapies.
Źródło:
European Journal of Clinical and Experimental Medicine; 2018, 1; 47-52
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
An overview of the preclinical and clinical studies of the effects of tumor treating fields on malignant glioma cells
Autorzy:
Bądziul, Dorota
Banaś-Ząbczyk, Agnieszka
Tabarkiewicz, Jacek
Powiązania:
https://bibliotekanauki.pl/articles/454690.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
anaplastic astrocytoma
glioblastoma multiforme
brain tumor
tumor treating fields
tumor therapy
Opis:
Anaplastic astrocytoma (AA, WHO grade III) and glioblastoma multiforme (GBM, WHO grade IV) are malignant tumors of the brain. The average survival time of patients with GMB is approximately one year and two years in the case of anaplastic astrocytoma with standard therapy based on surgical tumor resection followed by chemotherapy or radiotherapy. High invasiveness of gliomas, the ability of rapid division and so-called diffusive infiltration of tumor cells into normal brain tissue, which prevents complete surgical removal, are hallmarks of theses tumors. Therefore, new specific therapies for eliminating cancer cells are needed to treat this tumors. Recently, it has been demonstrated that alternating electric field, also known as tumor treating fields (TTFields) has a unique mechanism of destroying glioma cells. TTFields applies electromagnetic energy frequency-dependent and intensitydependent and disrupts cancer cell replication as they undergo mitosis. Futhermore, TTFields turn out to act comparably to conventional chemotherapeutics, lacking numerous side adverse associated with chemotherapy. The authors provide an up-todate review of the mechanism of action as well as preclinical and clinical data on TTFields.
Źródło:
European Journal of Clinical and Experimental Medicine; 2017, 2; 141-144
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Biological properties of Cistus species
Autorzy:
Stępień, Agnieszka
Aebisher, David
Bartusik-Aebisher, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/454751.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
biological properties
Cistus sp.
medicinal plants
Opis:
Aim. This paper presents a review of scientific studies analyzing the biological properties of different species of Cistus sp. Materials and methods. Forty papers that discuss the current research of Cistus sp. as phytotherapeutic agent were used for this discussion. Literature analysis. The results of scientific research indicate that extracts from various species of Cistus sp. exhibit antioxidant, antibacterial, antifungal, anti-inflammatory, antiviral, cytotoxic and anticancer properties. These properties give rise to the possibility of using Cistus sp. as a therapeutic agent supporting many therapies
Źródło:
European Journal of Clinical and Experimental Medicine; 2018, 2; 27-132
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The role of MRI in the central nervous system
Autorzy:
Leksa, Natalia
Aebisher, David
Bartusik-Aebisher, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/454852.pdf
Data publikacji:
2020-03-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
1H MRI
functional MRI
metabolic brain disfunctions
Opis:
Introduction. Magnetic Resonance Imaging (MRI) has modified the practice of radiology. MRI is base on safe interaction between radiowaves at a particular frequency and hydrogen nuclei in the body. Metabolic encephalophaties are by definition those disorder of the central nervous system that are not due primarily to structural abnormalities. Aim. Here we present the 1H MRI and functional MRI (fMRI) method applied to diagnosis of disorders of the central nervous system. Material and methods. Analysis of literature and self-research. Results.We have discussed the major MRI applications in the characteristic of the central nervous system. The relationship beteen the motion of flowing blood and the representation of the blood on images is complex. This work is an introduction to the basic ideas and techniques of fMRI. Therefore, both, 1H MRI and functional MRI, methods are ued in neuroscience. Conclusion. Nonivasive MRI and functional MRI are daily diagnostics methods in neurology.
Źródło:
European Journal of Clinical and Experimental Medicine; 2020, 1; 28-31
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Neoadjuvant therapy in breast cancer – objectives and tasks
Autorzy:
Ostańska, Elżbieta
Bartusik-Aebisher, Dorota
Aebisher, David
Kaznowska, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/454710.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
neoadjuvant therapy (NCT)
breast cancer (BC)
triple negative breast cancer (TNBC)
Opis:
Introduction. Neoadiuvant therapy (NCT) in the treatment of breast cancer is employed for patients with early stage disease or with inoperable disease. NCT can decrease the tumor volume. It can facilitate breast conservation therapy. Response to NCT is a strong predictor of outcome breast cancer (BC). Direct target therapies has markedly improved the result of treatment BC. Aim. Therapy for breast cancer continues to improve. The importance of tumor burden on local control rates will be in the future. Material and methods. This analysis was performed using a systematic literature search. Results. The latest scientific reports give hope for greater safety and a better life for patients based on optimized and effective therapy. Conclusion. Currently, improving the effectiveness of breast cancer treatment is mainly related to the optimal use of classic therapeutic strategies. New classes of substances have been approved for treatment or are in advanced stages of clinical development.
Źródło:
European Journal of Clinical and Experimental Medicine; 2019, 2; 153-156
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Inflammatory bowel disease: the function of metalloproteinases
Autorzy:
Pasternak, Grzegorz
Aebisher, David
Filip, Rafał
Bartusik-Aebisher, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/454718.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
inflammatory bowel disease
matrix metalloproteinases extracellular matrix
Opis:
Introduction. Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine. Aim. The aim of this work was to review the current literature regarding matrix metalloproteinases. The databases such as PubMed, ScienceDirect and Springer were utilized to search the literature for relevant articles. Materials and methods. An analysis of literature. We collected information, data, and examples of the function of metalloproteinases. Results. Herein we show that metalloproteinases play a role in such processes as the immune response, angiogenesis, the epithelial barrier function, fibrosis induced by the inflammatory process, and in the process of carcinogenesis. Conclusions. Further studies on the role of metalloproteinases in the process of carcinogenesis associated with inflammatory bowel diseases are required.
Źródło:
European Journal of Clinical and Experimental Medicine; 2018, 4; 346-349
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Determinants of women’s behavior in breast cancer prevention
Autorzy:
Nagórska, Małgorzata
Aksamit, Magdalena
Krygowska, Krystyna
Bassara-Nowak, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/454727.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
attitudes
breast cancer
knowledge
prophylaxis
Opis:
Introduction. According to statistics, breast cancer is the second leading cause of death in Poland. Progress in treatment and diagnosis gives an opportunity of a quick diagnosis, but women are reluctant to undergo prophylaxis screening. Aim. To identify women’s attitudes about breast cancer prophylaxis. Material and methods. The diagnostic survey was conducted in a group of 200 women. The research tool was the questionnaire developed by the authors. Results. Knowledge about breast cancer and prophylaxis was on an average level. Nearly half of the women surveyed (45.5%) declared that they do not ask for a breast examination while visiting a gynecologist. Only 26.8% of the surveyed women were systematically subjected to preventive examinations for breast cancer, while 18.7% of them performed breast self-examination. Every fifth respondent used invitation for a free mammogram. Conclusion. The women’s knowledge about breast cancer is average, but it does not translate into their attitudes towards the prevention of this cancer. Most women niether perform breast self-examination nor benefit from free prophylaxis programs. Younger respondents most often use the Internet. Education and place of residence do not affect the participation of women in preventive examinations for breast cancer.
Źródło:
European Journal of Clinical and Experimental Medicine; 2019, 2; 123-130
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Retrospective analysis of reactive hyperplastic lesions in the oral cavity
Autorzy:
Farynowska, Justyna
Błochowiak, Katarzyna
Trzybulska, Dorota
Wyganowska-Świątkowska, Marzena
Powiązania:
https://bibliotekanauki.pl/articles/454761.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
inflammatory fibrous hyperplasia fissuratum granuloma
peripheral giant cell granuloma irritation fibroma
pyogenic granuloma
Opis:
Introduction. Reactive hyperplastic lesions of the oral cavity are non-neoplastic lesions that result from low-grade chronic irritation of the oral mucosa. Objectives. The aim of this study was to present the epidemiological characteristics of reactive lesions. Materials and methods. The study was a retrospective analysis of the medical records of 116 patients with reactive lesions. The tissue specimens were obtained by biopsy. 115 patients underwent an excisional biopsy, whereas in one case an incisional biopsy was performed. Results. The most frequently encountered lesion was inflammatory fibrous hyperplasia (IFH) (n=37, 31.9%), followed by irritation fibroma (IF) (n=36, 31%), pyogenic granuloma (PG) (n=15, 12.9%), fissured granuloma (FG) (n= 14, 12.1%). The lesions were more commonly observed in females (n=70, 60.3%) than in males (n=46, 39.7%) with a ratio of 1.5:1, respectively. The buccal and labial mucosa were the most prevalent sites of reactive lesions. Most of the lesions were between >5 mm and ≤10 mm in diameter except for FGs, which were much bigger. Conclusions. Early detection and elimination of all potentially causative factors and irritants is a crucial matter, especially in the case of the vestibule of the oral cavity, which is the most susceptible area of the oral cavity
Źródło:
European Journal of Clinical and Experimental Medicine; 2018, 2; 92-96
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Medicinal & Aromatic Plants
Autorzy:
Domka, Wojciech
Aebisher, David
Truszkiewicz, Adrian
Bartusik-Aebisher, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/454771.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
phytotherapy
medicinal plants
otorhinolaryngology
Opis:
Introduction. The objective of this study is to discuss the potential of plants species in medical applications. Aim. The main purpose of this study is to discuss ethnobotanically selected plants used in medicine. Materials and methods. We analysed literature and collected information, data, and examples of selected plants used in medicine. Results. The literature shows that for several decades, the properties of medicinal plants have been investigated and reported in the biomedical and pharmaceutical literature. Conclusions. This review includes studies on plants material. The properties of various plants physiology were discuuses with the option for the use in phythotherapy
Źródło:
European Journal of Clinical and Experimental Medicine; 2018, 4; 350-358
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Imaging methods of early detection and screening for breast cancer. A review
Autorzy:
Gustalik, Joanna
Bartusik-Aebisher, Dorota
Aebisher, David
Kaznowska, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/454888.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
breast cancer
breast MRI
early detection
screening
Opis:
Introduction. Breast cancer is the most frequent neoplasm among women. That is the reason why scientists all over the world are attempting to improve early detection methods of this particular malignancy. Aim. The most common and most widely used examination methods for screening for and detecting breast cancer is presented herein. Material and methods. This review was performed according to systematic literature search of three major bibliographic databases. Results. Available data suggest that incidence and mortality in high-resource countries has been declining whereas incidence and mortality in low-resource countries has been increasing. Conclusion. The role of a physician is to select the most suitable one for each patient in order to obtain the best result. No matter the method however, between 2005 and 2011, the 5-year relative survival was found to be 89%. This is thought to be due to both the increase in utilization of population-wide screening, as well as advances in treatment.
Źródło:
European Journal of Clinical and Experimental Medicine; 2019, 2; 142-145
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Bladder Mullerianosis – a case report
Autorzy:
Ostańska, Elżbieta
Aebisher, David
Kaznowska, Ewa
Bartusik-Aebisher, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/454913.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
endocericosis
endosalpingiasis
mullerianosis
urinary bladder
Opis:
Introduction. Bladder mullerianosis is a rare and proliferative lesion that contains at least two types of ectopic Mullerian tissue in its wall. Aim. To present case of bladder mullerianosis. Description of case. The text contains a description of a clinical case of a 50-year-old woman admitted to a gynecological ward due to diarrheal symptoms and abdominal pain. In a CT examination of the abdominal cavity with contrast, within the posterior left-sided wall of the bladder a 43x25mm proliferative lesion suggestive of neoplastic character was revealed. Transurethral resection of the lesion (TURB) was performed. Histopathology revealed endosalpingiosis with small endocervical foci. The picture of hyperplasia met the criterion of mullerianosis. Conclusion. Bladder Mullerianosis is a very rare disease that occurs mainly in women of reproductive age. It has very good prognosis. It is important to differentiate the lesion with malignant tumor. The basis for the diagnosis is the histopathological examination of the lesion tissues taken during the surgery.
Źródło:
European Journal of Clinical and Experimental Medicine; 2019, 3; 277-280
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hyalinising clear cell carcinoma of salivary gland: a case report
Autorzy:
Osuchowski, Michał
Bartusik-Aebisher, Dorota
Kaznowska, Ewa
Aebisher, David
Powiązania:
https://bibliotekanauki.pl/articles/2037686.pdf
Data publikacji:
2020-06-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
cancer
hyalinising clear cell carcinoma salivary gland
Opis:
Introduction. Clear cell carcinoma, not otherwise specified/hyalinising clear cell carcinoma of the salivary gland (HCCC) is a malignancy that arises in minor salivary glands. It rarely leads to distant metastases or cancer-related death but has the potential for recurrence and focal metastases. Aim. A case is reported. Description of the case. A 72 years old female patient has reported to the Clinic of Otolaryngology with a tongue lesion. The patient had no history of malignancy. The lymph node has been surgically removed for further examination. Cords and nests of clear cells and cells with eosinophilic cytoplasm in a hyalinized stroma were identified within the lymph node. After the diagnosis the patient has been transferred to another Oncology Hospital for further treatment. Conclusion. The diagnosis of clear cell carcinoma may be challenging because many of it‘s features frequently overlap with other salivary gland lesions.
Źródło:
European Journal of Clinical and Experimental Medicine; 2020, 2; 127-130
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The larynx cancer in vitro study by MRI relaxtion time of water
Autorzy:
Domka, Wojciech
Ożóg, Łukasz
Bartusik-Aebisher, Dorota
Aebisher, David
Powiązania:
https://bibliotekanauki.pl/articles/2038279.pdf
Data publikacji:
2020-09-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
larynx tissue
magnetic resonance imaging
T2 mapping
T2 relaxation time
Opis:
Introduction. Squamous cell carcinoma (SCC) of the larynx accounts for a significant percentage of all head and neck cancers. Aim. In this paper we determine the differences in magnetic resonance relaxation time (MRI) of water in cancerous and healthy larynx tissues. Material and methods. This study is aimed on T2 MRI modalities for monitoring morphology of larynx tissue. Results. Our results showed that T2 MRI relaxation time measured in larynx tissue can be used to assess early cancer condition of larynx tissues. The changes of T2 MRI correspond to tumor growth within normal tissue. Conclusion. The study showed potential of MRI for the non-invasive monitoring of larynx condition.
Źródło:
European Journal of Clinical and Experimental Medicine; 2020, 3; 185-187
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Primary breast angiosarcoma – a case report
Autorzy:
Ostańska, Elżbieta
Aebisher, David
Kaznowska, Ewa
Bartusik-Aebisher, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/2040145.pdf
Data publikacji:
2020-12-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
breast biopsy histopathological examination
immunohistochemistry
Opis:
Introduction. Angiosarcoma is a rare breast cancer that can be primary or secondary after surgery or after breast cancer radiotherapy. It is important that breast angiosarcoma belongs to tumors with a non-specific clinical and radiological picture. Aim. The study of the biopsies contained aggressive vasomotor hyperplasia. Description of the case. The presented case concerns the primary angiosarcoma of the right breast in a 56-year-old woman who had never had a surgical procedure before, nor radiotherapy in the area of the breast. Conclusion. Histopathological examination supported by immunohistochemistry is a reliable and indispensable diagnostic element in the diagnosis of vascular sarcoma.
Źródło:
European Journal of Clinical and Experimental Medicine; 2020, 4; 331-334
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Numerous gastrointestinal tumors
Autorzy:
Przyczyna, Piotr
Trojnar, Elżbieta
Bartusik-Aebisher, Dorota
Aebisher, David
Powiązania:
https://bibliotekanauki.pl/articles/2040144.pdf
Data publikacji:
2020-12-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
gastrointestinal stromal tumor histopathological examination multiple neoplasms
small intestine
Opis:
Introduction. Gastrointestinal stromal tumor (GIST) is most often locate in the region of the stomach and the proximal part of the small intestine. Aim. The multiple histopathological examination is described. Description of the case. Multiple GISTs are rare neoplasms that originate from the interstitial cells are described. Conclussion. GIST can occur in any part of the gut, they are most common in the stomach and small intestine, and less frequent in the colorectum and esophagus. Although their pathogenesis and clinical manifestations are different, these tumor syndromes confer a high risk for developing multiple neoplasms.
Źródło:
European Journal of Clinical and Experimental Medicine; 2020, 4; 328-330
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
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