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    Wyświetlanie 1-2 z 2
    Tytuł:
    Glycosylation of immune system proteins and its role in autoimmune diseases and cancer
    Autorzy:
    Trzyna, Anna
    Tabarkiewicz, Jacek
    Mazur, Artur
    Powiązania:
    https://bibliotekanauki.pl/articles/1597351.pdf
    Data publikacji:
    2020-03-30
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    Glycosylation
    Immunity
    Cellular
    Humoral
    Autoimmune Diseases
    Opis:
    Introduction. Structural glycans have great biological significance and are involved in signaling and cell communication of the immune system. They are attached to proteins and lipids in an enzymatic process called glycosylation where glycosyltransferase and glycosidases bind sugar residues and lead to the formation of bioconjugates. Aim. In this paper we describe the importance of glycosylation in the immune system and its changes in diseases. Material and methods. This review was performed according to systematic literature search of major bibliographic databases. Results. Proper glycosylation ensures the functioning of the organism, however, defects in structural glycans of immune system changes their properties and can lead to disorders and further to autoimmune diseases. It has been also proven that glycosylation of autoimmune system is changed during cancer. In this paper we described types of structural glycans, significance of glycosylation of selected components of the immune system and its modifications in disorders. Conclusions. Knowledge about changes in the glycosylation in diseases is the key to understanding the processes of autoimmune diseases and may allow the development of new treatments in the future.
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2020, 1; 32-37
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Personality correlates in the tendency to incur debt in patients with and without osteoarthritis
    Autorzy:
    Łukasiewicz, Jacek
    Stencel, Marcin
    Raczkowski, Adam
    Cwynar, Andrzej
    Cwynar, Wiktor
    Saran, Tomasz
    Mazur, Anna
    Powiązania:
    https://bibliotekanauki.pl/articles/454971.pdf
    Data publikacji:
    2019
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    life on credit
    osteoarthritis
    personality
    Opis:
    Introduction. Osteoarthritis is the most common disease of the musculoskeletal system. Osteoarthritis progresses slowly, but with time it results in movement disability and chronic pain. Its progression is also significantly associated with personality functioning and the ability to make rational life choices regarding various aspects of human life, including the economic sphere. Aim. The aim of the research was to determine how personality correlates with a tendency towards indebtedness between patients with and without osteoarthritis. Material and methods. The researched sample consisted of two groups - 50 patients diagnosed with osteoarthritis hospitalized in the Department of General and Neuro Rehabilitation in the Institute of Rural Health in Lublin and 50 healthy people. The KOS-B Questionnaire, the IVE Questionnaire, the SES Scale, the SPP-25 Scale, the Delta Questionnaire and the APSZ questionnaire were used in the research. Results. In the group of patients with osteoarthritis, the leading correlates of indebtedness are: assessment of the stress situation related to the current economic situation seen as a threat, and perceiving it as harm or loss. In the healthy group, the leading correlates of incurring financial liabilities are impulsiveness, self-esteem, assessment of the stress situation related to the current economic situation seen as a threat, openness to new experiences and sense of humor, empathy, and the need for social approval. Conclusion. In the group of patients with osteoarthritis, the factor conducive to incurring financial liabilities is the assessment of the stressful situation related to the current economic situation seen as a threat, while perceiving it as harm or loss leads to abandoning reliance on credit. In the healthy group, the factors that favor this type of activity are impulsiveness, self-esteem, the assessment of the stress situation related to the current economic situation seen as a threat and the need for social approval; the factors protecting against indebtedness in healthy persons are openness to new experiences and sense of humor as well as empathy.
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2019, 1; 26-32
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-2 z 2

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