- Tytuł:
- Synthesis and fungistatic activity of aryl-substituted naphthalene- and indene-2-carbonitriles
- Autorzy:
-
Kozik, B
Burgieł, Z. J.
Sepioł, J. J.
Wilamowski, J.
Łuczyński, M. K.
Góra, M. - Powiązania:
- https://bibliotekanauki.pl/articles/363192.pdf
- Data publikacji:
- 2006
- Wydawca:
- Uniwersytet Warmińsko-Mazurski w Olsztynie
- Tematy:
-
grzyby fitopatogenne
WWA
aktywność fungistatyczna
ochrona roślin
phytopathogenic fungi
PAHs
fungistatic activity
plant protection - Opis:
- 4-Aryl-substituted 1-aminonaphthalene-2-carbonitriles and 3-phenyl-1-oxo-1H-indene-2-carbonitriles were prepared in a two--step synthesis from appropriate carbonyl compounds and were evaluated in vitro for growth-inhibiting activity against some phytopathogenic fungi: Fusarium culmorum, Penicillium expansum, Botrytis cinerea and Alternaria species. The results were compared with the activity of a commercial fungicide - captan. The highest fungistatic activity was revealed by 1-amino-4-phenylnaphthalene-2-carbonitrile. An efficient synthesis of 1-amino-4-arylnaphthalene-2-carbonitriles involves condensation of diarylacetaldehydes or 1,1-diarylacetones with malonodinitrile and cyclization of the obtained aryl-ylidenemalonodinitriles in concentrated sulfuric acid. The benzannulation reaction is accompanied by a quasi-aromatic rearrangement. The indenone derivatives were synthesized in the same manner from substituted benzophenones. As the formation of five-membered ring during the cyclization of diarylmethylidenemalonodinitriles was less effective, the rearrangement was not observed.
- Źródło:
-
Environmental Biotechnology; 2006, 2, 1; 20-25
1734-4964 - Pojawia się w:
- Environmental Biotechnology
- Dostawca treści:
- Biblioteka Nauki
Artykuł