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Wyszukujesz frazę "cells viability" wg kryterium: Temat


Wyświetlanie 1-2 z 2
Tytuł:
Mechanical and biological properties of carbon fiber-reinforced peek composite materials intended for laryngeal prostheses
Autorzy:
Smółka, Wojciech
Dworak, Michał
Noworyta, Bartłomiej
Gubernat, Maciej
Markowski, Jarosław
Błażewicz, Marta
Powiązania:
https://bibliotekanauki.pl/articles/285375.pdf
Data publikacji:
2019
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
composite materials
PEEK
mechanical properties
cells viability
Opis:
The work deals with the mechanical properties and biological behaviour of composite materials made of polyether ether ketone (PEEK) polymer and carbon fibers (CF) designed for laryngeal biomaterials. Two types of PEEK–based matrix composites containing carbon fibers in the form of cloth (2D) and short fibers (MD) were made. The composite samples were obtained via hot mol-ding of PEEK/CF prepregs. Mechanical durability of the composite samples aging in Ringer’s solution at 37oC was analyzed. The samples were dynami-cally loaded under bending force up to 106 cycles. The ultrasonic wave propagation method was applied to study changes in the composites. The mechanical changes were analyzed, taking into consideration the anisotropic structure of the composite samples. The layered composite samples were modified with multiwalled carbon nanotubes (CNTs). The changes in mechanical stability of the composite samples were not significant after fatigue testing up to 1·106cycles. The biological tests were carried out in the presence of hFOB-1.19-line human osteoblasts and HS-5-line human fibroblasts. The level of type I collagen produced from both types of cells was determined by ELISA test. The tests showed differen-ces between the samples with regard to the viability of the cells.
Źródło:
Engineering of Biomaterials; 2019, 22, 151; 2-8
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Chemical modification of poly ε-caprolactone with wollastonite and its influence on biological properties of osteoblast like-cells MG-63
Autorzy:
Ścisłowska-Czarnecka, A.
Menaszek, E.
Kołaczkowska, E.
Błażewicz, M.
Podporska, J.
Powiązania:
https://bibliotekanauki.pl/articles/284898.pdf
Data publikacji:
2011
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
polycaprolactone
wollastonite
osteoblast-like MG-63 cells
cell adhesion
viability
proliferation
alkaline phosphatase
Opis:
PCL (poly-ε-caprolactone) is a biocompatible and biodegradable polymer of aliphatic polyester group. However, PCL does not effectively bind to the bone in contrast to bioactive inorganic compounds such as wollastonite. For this wollastonite (WS) is regarded as a potential bioactive material for bone tissue engeenering although its main drawback is brittlennes. Therefore we synthesized polymer nanocomposite materials composed of poly-ε-caprolactone and wollastonite (PCL/wollastonite) containing either 0.5% or 5% of the latter modifying filler. And we aimed to verify biological properties of the nanocomposite PCL/WS materials, in comparison to the pure PCL, on cultures of osteoblast-like cells MG-63. The study revealed that the adherence of the osteoblast-like cells to the tested materials was enhanced by the PCL modification (PCL/5WS > PCL/0.5WS > PCL) while cell viability/proliferation was not altered. Furthermore, the activity of alkaline phosphatase indicative of osteoblast differentiation (maturation) was enhanced when the cells were cultured with either PCL/5WS or PCL/0.5WS. Overall, our results indicate that PCL-modified wollastonite improves biological properties of the basic biomaterial suggesting its potential usefulness/application for the bone tissue regeneration.
Źródło:
Engineering of Biomaterials; 2011, 14, 102; 11-14
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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