- Tytuł:
- In vitro evaluation of poly(L-lactide-co-glycolide) membrane
- Autorzy:
-
Krok, M.
Hess, R.
Wojak, I.
Kościelniak, D.
Scharnweber, D.
Pamuła, E. - Powiązania:
- https://bibliotekanauki.pl/articles/285820.pdf
- Data publikacji:
- 2010
- Wydawca:
- Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
- Tematy:
-
in vitro
membranes
bone defects - Opis:
- The aim of this study was to prepare and evaluate the properties of a new membrane dedicated for the treatment of bone defects in periodontology according to guided tissue regeneration (GTR) technique. The first part of this study was to prepare the membrane from resorbable poly(L-lactide-co-glycolide) (PLGA) and verify its microstructure. Biological evaluation was lead using the cells interesting from the point of view of GTR, e.g. human fibroblasts and mesenchymal stem cells (hMSC). It was found that the obtained membrane has asymmetric microstructure and defined pore size. Cell culture experiments show that the membrane is biocompatible with fibroblasts and hMSC. Both types of cell proliferated well on the membrane. HMSC cultured on the membrane exhibited better osteogenic differentiation and higher mineralization as compared to control tissue culture polystyrene.
- Źródło:
-
Engineering of Biomaterials; 2010, 13, 94; 7-10
1429-7248 - Pojawia się w:
- Engineering of Biomaterials
- Dostawca treści:
- Biblioteka Nauki
Artykuł