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    Wyświetlanie 1-7 z 7
    Tytuł:
    Correlation of vitamin D deficiency with mortality in critically ill patients admitted to the intensive care unit
    Autorzy:
    Joshi, Vidit Maheshkumar
    Wasnik, Seema Balkrishna
    Yadav, Amlendu
    Yadav, Rupesh
    Powiązania:
    https://bibliotekanauki.pl/articles/29432042.pdf
    Data publikacji:
    2024-03-31
    Wydawca:
    Towarzystwo Pomocy Doraźnej
    Tematy:
    Intensive care unit
    mortality
    vitamin D
    Opis:
    INTRODUCTION: Vitamin D, which is a fat-soluble vitamin, plays a key role in enhancing the intestinal absorption of calcium, magnesium and phosphate. In severely ill patients, vitamin D can adversely affect immune and metabolic functions, contributing to poorer outcomes. The aim of this study was to correlate vitamin D with mortality in critically ill patients. MATERIALS AND METHODS: prospective observational study was conducted, involving 162 patients in an intensive care unit (ICU). 162 patients were divided into two groups according to vitamin D Deficiency Group levels ≤ 20 ng/ml and Non vitamin D deficiency group levels <20 ng / ml and non-vitamin D deficiency group B levels > 20ng/ml. Data collected during the study included the APACHE II (acute physiology and chronic health evaluation) score at ICU admission, SOFA (sequential organ failure assessment) scores throughout the ICU stay, the need for mechanical ventilation, inotropic support, length of stay in ICU, and ICU outcomes, which were classified as either discharge or mortality. RESULTS: Of the 162 patient admitted to ICU, the prevalence of vitamin D deficiency in this study was 140 (86.4%) and nondeficient 22 (13.6%). The mortality rate in the vitamin D deficient group was 40% compared to 18.18% in the nondeficient group. The difference in mortality in both groups for mortality was statistically significant (p-value < 0.05). Vitamin D deficiency was not associated as an independent risk factor for ICU mortality [Odds ratio (OR) 1.220, 95% CI (0.825- 1.805) (p-value -0.320)]. CONCLUSIONS: The vitamin D-deficient group had a significantly higher mortality rate compared to the patient in the nondeficient group. But vitamin D deficiency was not found to be an independent risk factor for mortality.
    Źródło:
    Critical Care Innovations; 2024, 7, 1; 1-11
    2545-2533
    Pojawia się w:
    Critical Care Innovations
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Association of glycosylated hemoglobin with mortality of patients in intensive care unit: a prospective observation study
    Autorzy:
    Kumar, Damera Seshi
    Wasnik, Seema Balkrishna
    Yadav, Amlendu
    Yadav, Rupesh
    Powiązania:
    https://bibliotekanauki.pl/articles/29432036.pdf
    Data publikacji:
    2024-03-31
    Wydawca:
    Towarzystwo Pomocy Doraźnej
    Tematy:
    Glycated hemoglobin
    intensive care unit
    mortality
    Opis:
    INTRODUCTION: Glycated hemoglobin (HbA1c) is the most commonly used clinical test to estimate mean blood glucose during the past 2 to 3 months. In addition to diagnostic purposes, the HbA1c level also predicts diabetes complications. The aim of this study was to determine the association of glycosylated hemoglobin with mortality in intensive care unit (ICU). MATERIALS AND METHODS: A prospective observational study was conducted in the ICU with a total of 281 patients. These patients were classified into two groups based on their HbA1c levels: one group with HbA1c level < 6.5 % and another group with HbA1c level ≥ 6.5%. The following data were collected during the study period. Clinical details and scores such as the APACHE II score (Acute Physiology and Chronic Health Assessment) and daily SOFA (Sequential Organ Failure Assessment) scores for the period of stay in the ICU. ICU morbidities as the need for mechanical ventilation, the use of inotropes / vasopressors, the length of stay in the ICU, and the requirement of renal replacement therapy (RRT). The outcome measures were ICU mortality and 28-day mortality. RESULTS: Of 281 patients admitted to the ICU for more than 48 hours, 157 patients (55.9%) had HbA1c levels < 6.5%, with the remaining 124 (44.1%) had levels ≥ 6.5%. ICU mortality was present in 107 (38.07%) cases. ICU mortality was higher in patients in the HbA1c ≥ 6.5% group compared to the HbA1c < 6.5% group. This was statistically significant (p-value <0.001). Mortality at 28 days was observed in 125 (44.48%) cases. Patients with an HbA1c value ≥ 6.5%, there was a higher mortality at 28 days compared to patients with an HbA1c value < 6.5%. This was found to be statistically significant (p-value <0.001). CONCLUSIONS: The study showed that glycated hemoglobin levels (HbA1c) levels ≥ 6.5% had a significantly higher mortality rate compared to the patient in the HbA1c level < 6.5%.
    Źródło:
    Critical Care Innovations; 2024, 7, 1; 24-33
    2545-2533
    Pojawia się w:
    Critical Care Innovations
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Current situation’s analysis of the problem in intensive care of complicated community-acquired pneumonias in children
    Analiza aktualnego problemu w intensywnej terapii skomplikowanego pozaszpitalnego zapalenia płuc u dzieci
    Autorzy:
    Horodkova, Yuliia
    Powiązania:
    https://bibliotekanauki.pl/articles/1033273.pdf
    Data publikacji:
    2020
    Wydawca:
    Towarzystwo Pomocy Doraźnej
    Tematy:
    child
    intensive care units.
    plasmapheresis
    pneumonia
    Opis:
    INTRODUCTION: The leading place in the nosological structure of pathology in the lower respiratory tract is pneumonia. Community-acquired pneumonia (CAP) remains one of the most common causes of childhood morbidity and accounts for about 16% of all deaths in children under 5 years old. The article presents a review of publications of recent years using the databases PubMed, Scopus, Web of Science, Google Scholar regarding the current possibilities of intensive care of complicated community-acquired pneumonia (CCAP), problems of using extracorporeal detoxication methods (ECDM), the choice of starting antibacterial therapy and microbiological monitoring and the problem of determining the severity of endogenous intoxication syndrome in children with CCAP. PURPOSE: To analyze the relevance of intensive therapy in children with complicated community-acquired pneumonia, to consider current therapeutic interventions and the need to use extracorporeal detoxication methods in complex treatment based on the analysis of scientific literature data. CONCLUSIONS: The epidemiology of community-acquired pneumonia is currently characterized by an increasing trend in morbidity and mortality worldwide. Plasmapheresis is not first-line therapy, because antibacterial drug (ABD), conservative detoxication, respiratory support are the mainstay of treatment like for other infections, but in case of CCAP the course of basic therapy is often not enough and then there is a need for ECDM. Identification of causative microorganisms in children with CCAP remains a constant problem. In most cases, therapy is prescribed empirically and knowledge of local epidemiology, the structure of ABD resistance is an important platform for improving antibacterial therapy. The optimal therapeutic approach for CCAP remains open to research.
    WSTĘP: Wiodącym miejscem w strukturze nosologicznej patologii dolnych dróg oddechowych jest zapalenie płuc. Pozaszpitalne zapalenie płuc (CAP) pozostaje jedną z najczęstszych przyczyn zachorowań i zachorowań wśród dzieci na około 16% wszystkich zgonów dzieci poniżej 5 lat. Artykuł przedstawia przegląd publikacji z ostatnich lat z korzystaniem baz danych: PubMed, Scopus, Web of Science, Google Scholar w zakresie obecnych możliwości intensywnej opieki nad skomplikowanym pozaszpitalnym zapaleniem płuc (CCAP), problemów ze stosowaniem metod detoksykacji pozaustrojowej (ECDM), rozpoczęcia terapii przeciwbakteryjnej i monitorowania mikrobiologicznego oraz problemu ustalenia nasilenia zespołu zatrucia endogennego u dzieci z CCAP. CEL: Analiza znaczenia intensywnej terapii u dzieci ze skomplikowanym pozaszpitalnym zapaleniem płuc, ocena interwencji terapeutycznych i potrzeb stosowania złożonych metod detoksykacji pozaustrojowej w leczeniu opartym na analizie danych z literatury naukowej. WNIOSKI: Epidemiologia pozaszpitalnego zapalenia płuc charakteryzuje się obecnie rosnącą tendencją w chorobowości i śmiertelności na całym świecie. Plazmafereza nie jest leczeniem pierwszego rzutu, ponieważ lek przeciwbakteryjny (ABD), konserwatywna detoksykacja i wspomaganie oddychania są podstawą leczenia, podobnie jak w przypadku innych infekcji, ale w przypadku CCAP przebieg podstawowej terapii często nie wystarcza, a następnie istnieje potrzeba ECDM. Identyfikacja mikroorganizmów u dzieci z CCAP pozostaje stałym problemem. W większości przypadków terapia jest przepisywana empirycznie na podstawie znajomości lokalnej epidemiologii, a struktura oporności na ABD jest ważną składową poprawy działania terapii przeciwbakteryjnej. Optymalne podejście terapeutyczne do CCAP wymaga dalszych badań.
    Źródło:
    Critical Care Innovations; 2020, 3, 2; 29-42
    2545-2533
    Pojawia się w:
    Critical Care Innovations
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Acute hypersensitivity reaction following intravenous ferric carboxymaltose injection for iron deficiency anaemia: a case report
    Autorzy:
    Kumar, Neeraj
    Gautam, Preeti Bala
    Ahmad, Sarfaraz
    Qutub, Danish
    Prasad, Indira
    Powiązania:
    https://bibliotekanauki.pl/articles/29432056.pdf
    Data publikacji:
    2023
    Wydawca:
    Towarzystwo Pomocy Doraźnej
    Tematy:
    Ferric carboxy maltose
    hypersensitivity reaction
    intensive care unit
    Opis:
    Ferric carboxymaltose (FCM) is a non-dextran iron preparation used for intravenous treatment of iron deficiency anaemia (IDA) in adult patients with intolerance or poor response to oral iron therapy. Acute hypersensitivity reactions (HSRs) during iron infusions are very rare but can be life-threatening even after receiving a prior test dose. Here, we report a case of 42 years old female patient who underwent total laparoscopic hysterectomy with bilateral salpingo-oophorectomy. On the next postoperative day she received an injection of ferric carboxy maltose. She was diagnosed with IDA. She presented with the picture of an adverse drug reaction due to injection FCM. She was managed with oxygen, vasopressors, antihistaminics, intravenous fluids and, corticosteroids. She recovered well within 24 hours of intensive care unit admission following this adverse drug reaction. So, careful and precise observation is required in management of adverse reaction following ferric carboxymaltose and prompt recognition and treatment based on severity is warranted.
    Źródło:
    Critical Care Innovations; 2023, 6, 1; 41-45
    2545-2533
    Pojawia się w:
    Critical Care Innovations
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Acute naphthalene toxicity following ingestion of mothballs and ethyl alcohol: a case report
    Autorzy:
    Roshan, Nikesh Kumar
    Vishwas, Kirti
    Kumar, Neeraj
    Powiązania:
    https://bibliotekanauki.pl/articles/29432052.pdf
    Data publikacji:
    2023
    Wydawca:
    Towarzystwo Pomocy Doraźnej
    Tematy:
    Naphthalene balls
    mothballs
    ethyl alcohol
    toxicity
    intensive care unit
    Opis:
    Naphthalene poisoning is an uncommon poisoning due to its pungent smell, taste, insolubility in water, and poor absorption from the gut following exposure to naphthalene-containing compounds such as mothballs. Paradichlorobenzene has been reported to dissolve more quickly in alcohol. Within a period of 48-96 hours following naphthalene mothball exposure patient presents with acute onset of non-bloody bilious vomiting, dark brown urine and watery diarrhoea. We present a diagnostic and therapeutic challenge while treating a 27 years old male admitted to the intensive care unit with features of acute naphthalene-toxicity, methemoglobinemia and acute kidney injury following accidental ingestion of mothballs and ethyl alcohol. His vital signs at the time of intensive care unit admission included fever, tachycardia, and hypotension, and his laboratory workup demonstrates hyperbilirubinemia with indirect predominance, hemolytic anaemia, methemoglobinemia, and renal dysfunction. Treatment options include supportive care, red cell transfusion, ascorbic acid, methylene blue, and N-acetylcysteine. The importance of obtaining a careful history and clinical findings is of paramount importance, especially in making the right diagnosis and a successful outcome largely depends on it.
    Źródło:
    Critical Care Innovations; 2023, 6, 1; 29-35
    2545-2533
    Pojawia się w:
    Critical Care Innovations
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Evaluation of patients with candida infections in a tertiary care hospital’s general intensive care unit in Turkey.
    Autorzy:
    Ceylan, İlkay
    Korkmaz, Hamide Ayben
    Karakoç, Ebru
    Powiązania:
    https://bibliotekanauki.pl/articles/2054911.pdf
    Data publikacji:
    2022-06-30
    Wydawca:
    Towarzystwo Pomocy Doraźnej
    Tematy:
    Candidemia
    sepsis
    non-albicans
    intensive care unit
    candida species
    Opis:
    INTRODUCTION: : Studies indicate that approximately 90% of the patients followed in the ICU have Candida spp colonization. In this study we aimed to elucidate the epidemiology, characteristics, management and outcomes of patients with candidemia in the intensive care unit of a training and research hospital. MATERIAL AND METHODS: All patients over the age of 18 who were hospitalized in general intensive care unit more than 24 hours between 2013 and 2019 were included in the this retrospective study. RESULTS: A total of 43 critically ill patients with blood cultures positive for Candida spp. have been enrolled in this retrospective analysis. The duration of stay in the intensive care unit of the survivors was approximately 53 days, while the average length of stay in the intensive care unit of the non survivors was 16 days, and this difference was statistically significant (p<0.05), 89.7% of septic patients with candidemia died the intensive care unit. There was a statistically significant difference between the two groups in terms of platelets, urea and systolic blood pressure (p<0.05), the mean platelet and systolic blood pressure values of the surviving patients were higher than the deceased individuals, while the urea value was lower. The average fungal growth time of the surviving individuals was 17 days, while this period was 1 day in the non-survivor patients. CONCLUSIONS: The mortality rate was higher in patients with sepsis and concomittant candida infection at very soon days of ICU hospitalization. Early administration of empirical antifungal therapy with coverage of non-albicans should be considered for septic patients.
    Źródło:
    Critical Care Innovations; 2022, 5, 2; 1-10
    2545-2533
    Pojawia się w:
    Critical Care Innovations
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Prevalence and outcome of infections in intensive care units of a tertiary care hospital in north India.
    Autorzy:
    Malik, Samiullah Sami
    Maqbool, Muzaffar
    Rafi, Asma
    Kokab, Najma
    Powiązania:
    https://bibliotekanauki.pl/articles/2054909.pdf
    Data publikacji:
    2022-06-30
    Wydawca:
    Towarzystwo Pomocy Doraźnej
    Tematy:
    Intensive Care Units
    mortality
    nosocomial infections
    Sequential Organ Failure Assessment (SOFA)
    Opis:
    INTRODUCTION: Infection is a major cause of morbidity and mortality in Intensive Care Units (ICUs), more so in resource limited ICUs of low and lower-middle income countries. However relatively little information is available about epidemiology and outcome of such infections in our part of the world. The point was to provide information about the prevalence and outcome of primary and secondary (nosocomial) infections in ICUs. MATERIAL AND METHODS: 257 adult patients admitted in medical and surgical ICUs over a period of 9 months were enrolled in the study. Patients fulfilling sepsis 3 criteria were categorized under “prevalence of the infections” and patients who developed infections after 48 hours of admission in ICUs were categorized under “secondary (nosocomial) infections”. Sequential Organ Failure Assessment score (SOFA score) was calculated at admission and after 72 hours of ICU stay. The patients were followed for 30 days. RESULTS: Patients were distributed in two groups: 153 (59.5%) medical ICU and 104 surgical ICU patients. Prevalence of primary infection was significantly higher in medical ICU patients (p value < 0.05). A total of 93(60.8%) patients in medical ICU and 50(48.1%) patients in surgical ICU were admitted as primary infections (p value < 0.001). Secondary (nosocomial) infections occurred in 30 (19.6%) patients in medical ICU and 15 (14.4%) patients in surgical ICU (p-value 0.283). The average length of stay was 14 days in patients with nosocomial infections and 3.5 days for patients without secondary infections (p-value < 0.001). Out of total of 188 infected patients, 80 (42.5%) died whereas 17 (24.6%) of the 69 patients without infection expired (p-value 0.008). 112 patients with mean SOFA score of 11.35 ± 2.71 expired while as 145 patients with mean SOFA score of 5.84 ± 1.92 survived (p value < 0.001). CONCLUSIONS: The prevalence of infections was more in medical ICU than in surgical ICU. The nosocomial infections significantly increase the average length of stay in ICUs. Mortality was significantly more in patients admitted with infection in Intensive Care Units. The higher the SOFA score, greater the mortality.
    Źródło:
    Critical Care Innovations; 2022, 5, 2; 20-28
    2545-2533
    Pojawia się w:
    Critical Care Innovations
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-7 z 7

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