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    Wyświetlanie 1-3 z 3
    Tytuł:
    Modifiable lifestyle factors and ovarian cancer incidence in women
    Autorzy:
    Plagens-Rotman, K.
    Chmaj-Wierzchowska, K.
    Pieta, B.
    Bojar, I.
    Powiązania:
    https://bibliotekanauki.pl/articles/2081558.pdf
    Data publikacji:
    2018
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    ovarian cancer
    risk factors
    lifestyle
    the odds ratio
    disease
    Opis:
    Introduction. A correct diet plays an important role in the prevention of malignant tumours. The risk of the disease may be reduced by introducing a number of changes to the daily diet. The most important changes concern the amount of fat in the diet, dietary fibre, antioxidants in the food and the reduction of substances having a significant impact on the development of malignant tumours. Objective. The aim of the study is to analyse the role of selected modifiable lifestyle factors affecting the development of ovarian cancer. Materials and method. The study covered healthy women and women with diagnosed ovarian cancer. A total of 850 women aged between 21–84 were studied. The study included women visiting the Gynaecology and Obstetrics Hospital of the University of Medical Sciences in Poznan, Poland, between 2011–2013. Patients recognized with malignant ovarian cancer were qualified into the study based on the histopathological examination of the material obtained during surgery. Results. Respondents who consumed fruit and vegetables several times a week have the odds ratio OR = 0.29 level; 95% CI 0.04–2.01 (p =.2085), compared to women not consuming fruit and vegetables at all. Consumption of 100 g of French fries and potato chips several times a week, results in a 2-fold increase in ovarian cancer. The OR for this group of women amounts to 2.06; 95% CI 0.53–7.99 (p=.2966). Conclusions. A diet rich in fruit and vegetables, including bulb vegetables, and grain products containing whole grains, should be introduced. It is recommended that the consumption of popular fast foods be eliminated.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2018, 25, 1; 36-40
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Urban and rural differences in characteristics of ovarian cancer patients
    Autorzy:
    Szpurek, D.
    Moszynski, R.
    Szubert, S.
    Sajdak, S.
    Powiązania:
    https://bibliotekanauki.pl/articles/51471.pdf
    Data publikacji:
    2013
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    urban area
    rural area
    differentiation
    ovarian cancer
    patient
    residence place
    diagnosis
    Opis:
    Introduction and objective. The aim of the study was evaluation of the urban and rural differences in ovarian cancer patients’ characteristics at the moment of diagnosis. Materials and methods. The study comprised women with ovarian cancer diagnosed and treated in the Division of Gynecological Surgery of Poznan University of Medical Sciences between 2004–2011. The patients were divided into 3 groups based on their place of residence: 1) patients residing in large cities (over 50,000 people), 2) inhabitants of small towns (below 50,000 people), 3) women from rural areas. Results. Among the studied groups of patients no differences were found in the FIGO stage at diagnosis (p=0.453), histological grade of the tumour (p=0.916), histopathological types of ovarian neoplasms (p=0.431), median tumour volume (p=0.855), presence of fluid in the pouch of Douglas (p=0.872). Women with ovarian cancer residing in large cities had lower median parity (p=0.0005), higher education level status (p=0.0001), and experienced menarche at an earlier age (p=0.039). There were no differences in the use of oral contraception (p=0.93) and body mass index (p=0.23) between the women included in the study. Conclusions. There were no differences in advancement of ovarian cancer at the moment of diagnosis or in tumour type and size between women residing large cities, small towns and rural areas. Several ovarian cancer risk factors were more common among ovarian cancer patients living in urbanized areas.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2013, 20, 2
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Peroxiredoxin-1 as a prognostic factor in patients with ovarian cancer
    Autorzy:
    Sieńko, J.
    Teliga-Czajkowska, J.
    Przytula, E.
    Czajkowski, K.
    Smolarczyk, R.
    Nowis, D.
    Powiązania:
    https://bibliotekanauki.pl/articles/2085041.pdf
    Data publikacji:
    2019
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    Peroxiredoxin-1
    PRDX-1
    ovarian cancer
    overall survival
    disease free survival
    Opis:
    Introduction and objective. Peroxiredoxin-1 (PRDX-1) belongs to a family of antioxidant enzymes and has proved to be a versatile molecule regulating cell growth, differentiation and apoptosis. PRDX1-regulated signaling pathways play an important role in the progression and metastasis of human tumours, especially in breast, esophageal and lung cancers. The aim of the study was to evaluate the expression of PRDX-1 in ovarian cancer tissues, and to test the clinical value of PRDX-1 as a prognostic factor in this malignancy. Materials and method. PRDX-1 expression was assessed by automated immunohistochemistry in tumours taken from 55 patients with ovarian cancer during primary surgery. Specimen were formalin-fixed and preserved in paraffin-embedded blocks. The results were correlated with clinicopathological data. Results. A high expression of PRDX-1 was observed in 20% of cases, and was associated with worse compliance to chemotherapy protocol (P<0.002), worse response to chemotherapy (P<0.04), and higher levels of CA 125 after the 1st line treatment (P<0.004). PRDX-1 positive subjects had a significantly lower 5-year disease-free survival (9.1% vs. 42.6%, P<0.01) and a lower 5-year overall survival (9.1% vs. 56.7%; P<0.002). Multivariate analysis showed that a high expression of PRDX-1 is an independent prognostic factor of poor, overall survival (P<0.002) and a disease-free survival (P<0.01). Conclusion. Results of the study show that PRDX-1 expression in tumour tissues can be another biomarker of prognosis in patients with ovarian cancer.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2019, 26, 3; 415-419
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-3 z 3

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