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Wyszukujesz frazę "Roszkiewicz, A." wg kryterium: Autor


Wyświetlanie 1-2 z 2
Tytuł:
Potential occupational and environmental factors in SSc onset
Autorzy:
Walecka, I.
Roszkiewicz, M.
Malewska, A.
Powiązania:
https://bibliotekanauki.pl/articles/2081975.pdf
Data publikacji:
2018
Wydawca:
Instytut Medycyny Wsi
Tematy:
systemic sclerosis
connective tissue disease
environmental factors
occupational exposure
silica
Opis:
Introduction and objective. Systemic sclerosis [SSc; scleroderma] is a rare, connective tissue disorder affecting all organs and systems. The primary feature of this disease is a chronic, progressive fibrosis due to excessive production of collagen and other components. There are two subsets of systemic sclerosis: 1) diffused SSc (dSSc), 2) limited SSc (lSSc) and 3) scleroderma without sclerosis (SSSC). The presented review is an attempt to summarize recent data regarding environmental and occupational factors in SSc onset. State of knowledge. There are many factors to be taken under consideration with SSc onset, although a strong correlation has been established for only a few. The most distinct factors are: crystalline silica and organic solvents (such as white spirit, aromatic, aliphatic-chain, chlorinated solvents, ketones, welding fumes). For other factors, which include abstestos, air pollution, other chemicals, silicone breast implants, tobacco smoking, drug reactions, diet influence and exposure to heavy metals, the jury is still out, and their position in SSc onset needs further studies. Conclusions. Although the pathogenesis of scleroderma remains unclear, there is a marked correlation between the onset of SSc and certain environmental or occupational factors.
Źródło:
Annals of Agricultural and Environmental Medicine; 2018, 25, 4; 596-601
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Environmental risk factors and epigenetic alternations in psoriasis
Autorzy:
Roszkiewicz, M.
Dopytalska, K.
Szymańska, E.
Jakimiuk, A.
Walecka, I.
Powiązania:
https://bibliotekanauki.pl/articles/2085926.pdf
Data publikacji:
2020
Wydawca:
Instytut Medycyny Wsi
Tematy:
psoriasis
habits
environmental factors
epigenetic alternations
Opis:
Introduction and objective. Psoriasis isa quite common, chronic and immune-mediated skin disorder. The prevalence of psoriasis differs in various countries, but it is said to affect 2% of the world’s population in general. Psoriasis has many different clinical features but all lesions have the same characteristic: erythema, thickening and scale, although other clinical features are also connected, such as psoriatic arthritis, obesity and metabolic syndrome. All of these may lead to conditions impairing the quality of life. This review is an attempt to summarize recent data regarding environmental factors, together with epigenetic markers and processes playing an important role in psoriasis. State of knowledge. Many different environmental factors play a role in genetically predisposed patients. This is causes epigenetic alternations which may be a linking part in the whole process. Many studies have indicated a connection between psoriasis and various genes and antigens. The presence of HLA-Cw6 is common as well a strong link between its presence and the onset of psoriasis being observed. The main alternations are DNA methylation, histone’s modifications and the role of microRNA. Excessive reaction is usually not present without a triggering factor. Environmental factors are mostly rated, such as drugs, life style and habits (smoking, alcohol), diet, physical trauma (skin injury provoking Koebner phenomenon), stress, microorganism and infections. Conclusions. The correlation between pathogenesis of psoriasis and environmental risk factors, together with epigenetic alternations still require more investigation. Education about diet habits, nutrition, weight loss and healthy lifestyle seems to be important during the treatment of psoriasis.
Źródło:
Annals of Agricultural and Environmental Medicine; 2020, 27, 3; 335-342
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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