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Wyświetlanie 1-2 z 2
Tytuł:
Influence of dietary calcium intake on quantitative and qualitative parameters of bone tissue in Polish adults
Autorzy:
Skowrońska-Jóźwiak, Elżbieta
Jaworski, Maciej
Lorenc, Roman
Lewiński, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/990986.pdf
Data publikacji:
2016
Wydawca:
Instytut Medycyny Wsi
Tematy:
calcium intake
bone mineral density
bone stiffness
Opis:
Introduction. The objective of the study was to assess dietary calcium intake in the Polish population and its influence on selected parameters of bone tissue. Materials and method. 1,129 osteoporosis treatment–naive subjects, aged 20–80 years, randomly selected, were involved in the study. Bone status was established using densitometry of spine and hip and quantitative ultrasound of the calcaneus. Dietary calcium intake was calculated according to data gathered in a questionnaire. Results. Median calcium intake was 746 mg; 72% of subjects had calcium intake below the recommended dose. Calcium intake correlated negatively with age (r = -0.15; p<0.001) and positively with BMD in the spine (r = 0.06; p<0.05) and in the femoral neck (r = 0.07; p < 0.05). In subjects with the lowest calcium intake, a significantly lower femoral neck BMD and heel stiffness was noticed than in subjects with the highest calcium intake. However, multiple regression analysis showed that dietary calcium was not a predictor of low BMD, both in the hip and spine, as well as of bone stiffness in contrast to age, low BMI and female gender (p<0.0001). In all factors regression analysis, a weak influence of calcium intake on BMD was shown only in the subgroup of premenopausal women (β = 0.1; p<0.05). Conclusions. In most subjects, dietary calcium intake was below the recommended dose; however, its influence on bone seems to be weak, except for persons with the greatest deficiency of dietary calcium and the subgroup of premenopausal women.
Źródło:
Annals of Agricultural and Environmental Medicine; 2016, 23, 3
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Melatonin reverses the enhanced oxidative damage to membrane lipids and improves skin biophysical characteristics in former-smokers - a study in postmenopausal women
Autorzy:
Sagan, Dorota
Stępniak, Jan
Gesing, Adam
Lewiński, Andrzej
Karbownik-Lewińska, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/987005.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
smoking
former-smokers
never-smokers
postmenopausal women
oxidative stress
lipid peroxidation
skin biophysical
characteristics
sebum
moisture
elasticity
Opis:
Introduction and objective. Protective antioxidative effects of melatonin have been repeatedly documented in experimental and clinical studies. One of the most spectacular exogenous prooxidative agents is cigarette smoking. The aim of the study was to evaluate the level of oxidative damage to membrane lipids (lipid peroxidation; LPO) in blood serum, and in epidermis exfoliated during microdermabrasion collected from former-smokers who were treated with melatonin. Materials and Method. The study was performed in postmenopausal women. Ninety (90) female volunteers, aged 46–67 years, were enrolled. Two major groups, i.e. never-smokers (n=44) and former-smokers (n=46), were divided into: Control, melatonin topical skin application, Restructurer (containing antioxidants) topical skin application, and melatonin oral treatment. Microdermabrasion was performed at point ‘0’, after 2 weeks, and after 4 weeks of treatment. The following parameters were measured: LPO in blood serum, LPO in epidermis exfoliated during microdermabrasion, and skin biophysical characteristics, such as sebum, moisture, elasticity, and pigmentation. Malondialdehyde+4-hydroxyalkenals level (LPO index) was measured spectrophotometrically. Results. Melatonin oral treatment significantly reversed the increased serum LPO level in former-smokers already after 2 weeks of treatment. In a univariate regression model, LPO blood level constituted the only independent factor negatively associated with melatonin oral treatment. After 4 weeks of treatment, melatonin given orally increased skin sebum, moisture and elasticity levels, and melatonin applied topically increased sebum level. Conclusion. Exogenous melatonin reverses the enhanced oxidative damage to membrane lipids and improves skin biophysical characteristics in former-smokers.
Źródło:
Annals of Agricultural and Environmental Medicine; 2017, 24, 4
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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