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    Wyświetlanie 1-4 z 4
    Tytuł:
    Mechanical guidelines on the properties of human healthy arteries in the design and fabrication of vascular grafts: experimental tests and quasi-linear viscoelastic model
    Autorzy:
    Faturechi, Rahim
    Hashemi, Ata
    Abolfathi, Nabiollah
    Solouk, Atefeh
    Powiązania:
    https://bibliotekanauki.pl/articles/307007.pdf
    Data publikacji:
    2019
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    elastyczność
    model konstytutywny
    tętnica
    elasticity
    constitutive model
    human artery
    artificial artery
    quasi-linear viscoelasticity
    Opis:
    Knowledge of mechanical behavior of healthy human arteries as the guidelines to target properties of vascular grafts deserves special attention. There is a lack of mathematical model to characterize mechanical behavior of biomaterial while many mathematical models to reflect mechanics of human arteries have been proposed. The objective of this paper was set to measure mechanical properties of healthy human arteries including Common Carotid Artery (CCA), Abdominal Aorta Artery (AAA), Subclavian Artery (SA), Common Iliac Artery (CIA) and Right and Left Iliac Artery (RIA and LIA) and compare them to those of commercial ePTFE and Dacron®. Methods: Series of stress relaxation and strain to failure tests vere performed on all samples. The experimental data was utilized to develop quasi-linear viscoelastic (QLV) model of both natural and artificial arteries. Results: ePTFE is the stiffest sample, while the CCA is the most compliant one among all. RIA and CIA are more viscous than the other natural arteries, while AA and CCA are less viscous. The proposed model demonstrated an accurate fit to the experimental results, a proof of its ability to model both nonlinear elasticity and viscoelasticity of the human arteries and commercial ones. Conclusions: ePTFE and Dacron® are much stiffer than human arteries that may lead to the disruption of blood hemodynamic and may not be biomechanically feasible as a replacement.
    Źródło:
    Acta of Bioengineering and Biomechanics; 2019, 21, 3; 13-21
    1509-409X
    2450-6303
    Pojawia się w:
    Acta of Bioengineering and Biomechanics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Hemodynamic impacts of left coronary stenosis : a patient-specific analysis
    Autorzy:
    Chaichana, T.
    Sun, Z.
    Jewkes, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/306747.pdf
    Data publikacji:
    2013
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    coronary artery disease
    computational fluid dynamics (CFD)
    wall shear stress
    tętnica wieńcowa
    dynamika cieczy
    naprężenie
    Opis:
    This study analyses the hemodynamic variations surrounding stenoses located at the left coronary bifurcation, and their influence on the wall shear stress (WSS) in realistic coronary geometries. Four patients with suspected coronary artery disease were chosen, and coronary models were reconstructed based on high-resolution CT data. The coronary stenoses were observed at the left circumflex and left anterior descending branches, resulting in a lumen narrowing of >50%. Flow analysis was performed using computational fluid dynamics, to simulate the cardiac flow conditions of the realistic individual patient geometry. Blood flow and WSS changes in the left coronary artery were calculated throughout the entire cardiac phases. Our results revealed that the recirculation regions were found at the poststenotic locations. WSS was found to increase at the stenotic positions in all four patients. There is a strong correlation between coronary stenosis and the hemodynamic changes, which are reflected in blood flow pattern and WSS, based on the realistic left coronary geometries.
    Źródło:
    Acta of Bioengineering and Biomechanics; 2013, 15, 3; 107-111
    1509-409X
    2450-6303
    Pojawia się w:
    Acta of Bioengineering and Biomechanics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Numerical and experimental analysis of balloon angioplasty impact on flow hemodynamics improvement
    Autorzy:
    Tomaszewski, Michał
    Sybilski, Kamil
    Małachowski, Jerzy
    Wolański, Wojciech
    Buszman, Piotr P.
    Powiązania:
    https://bibliotekanauki.pl/articles/27324133.pdf
    Data publikacji:
    2020
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    angioplasty
    stent
    artery
    hemodynamics
    cfd analysis
    PIV method
    angioplastyka
    tętnica
    hemodynamika
    analiza CFD
    metoda PIV
    Opis:
    Purpose: The paper focuses on the numerical and experimental evaluation of the fluid flow inside chosen fragments of blood vessels. In the first stage of the study, the experimental tests were conducted using a research test stand, designed to be used in this evaluation. The study evaluated the blood flow through a silicone vessel with an implanted coronary stent. Methods: The PIV method was used in order to visualize the flow vectors inside a silicone vessel. Deformed vessel geometry implemented for computational fluid dynamics purposes was obtained owing to a non-linear simulation of the stent expansion (angioplasty process) in a silicone vessel. Additionally, a vessel model with a statistical 55% area stenosis and an irregular real vessel with an atherosclerotic plaque were also subjected to analysis from the hemodynamic flow point of view. A vessel with a statistical stenosis was also used to simulate the angioplasty process, which resulted in obtaining a flow domain for the vessel with an atherosclerotic plaque after the stent implantation. Results: For each case, distributions of parameters such as OSI or TAWSS were also analyzed and discussed. The areas of low TAWSS values appear close to the stent struts. Conclusions: Stents with increased diameters, compared to the normal vessel diameter, create a higher risk of occurrence of the areas with low WSS values. Excessive stent deformation can cause inflammation by injuring the vessel and can initiate the restenosis and thrombotic phenomena through the increased vessel diameter.
    Źródło:
    Acta of Bioengineering and Biomechanics; 2020, 22, 3; 169--183
    1509-409X
    2450-6303
    Pojawia się w:
    Acta of Bioengineering and Biomechanics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Investigation of blood flow rheology using second-grade viscoelastic model (Phan-Thien–Tanner) within carotid artery
    Autorzy:
    Ramiar, A.
    Larimi, M. M.
    Ranjbar, A. A.
    Powiązania:
    https://bibliotekanauki.pl/articles/307522.pdf
    Data publikacji:
    2017
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    tętnica szyjna
    model lepkoplastyczny
    przepływ pulsujący
    naprężenie ścinające
    OpenFOAM
    carotid artery
    viscoelastic model
    pulsatile flow
    shear stress
    Opis:
    Purpose: Hemodynamic factors, such as Wall Shear Stress (WSS), play a substantial role in arterial diseases. In the larger arteries, such as the carotid artery, interaction between the vessel wall and blood flow affects the distribution of hemodynamic factors. The fluid is considered to be non-Newtonian, whose flow is governed by the equation of a second-grade viscoelastic fluid and the effects of viscoelastic on blood flow in carotid artery is investigated. Methods: Pulsatile flow studies were carried out in a 3D model of carotid artery. The governing equations were solved using finite volume C++ based on open source code, OpenFOAM. To describe blood flow, conservation of mass and momentum, a constitutive relation of simplified Phan-Thien–Tanner (sPTT), and appropriate relations were used to explain shear thinning behavior. Results: The first recirculation was observed at t = 0.2 s, in deceleration phase. In the acceleration phase from t = 0.3 s to t = 0.5 s, vortex and recirculation sizes in bulb regions in both ECA and ICA gradually increased. As is observed in the line graphs based on extracted data from ICA, at t = 0.2 s, τyy is the maximum amount of wall shear stress and τxy the minimum one. The maximum shear stress occurred in the inner side of the main branch (inner side of ICA and ECA) because the velocity of blood flow in the inner side of the bulb region was maximum due to the created recirculation zone in the opposite side in this area. Conclusions: The rheology of blood flow and shear stress in various important parts (the area that are in higher rates of WSS such as bifurcation region and the regions after bulb areas in both branches, Line1–4 in Fig. 7) were also analyzed. The investigation of velocity stream line, velocity profile and shear stress in various sections of carotid artery showed that the maximum shear stress occurred in acceleration phase and in the bifurcation region between ECA and ICA which is due to velocity gradients and changes in thinning behavior of blood and increasing strain rate in Newtonian stress part.
    Źródło:
    Acta of Bioengineering and Biomechanics; 2017, 19, 3; 27-41
    1509-409X
    2450-6303
    Pojawia się w:
    Acta of Bioengineering and Biomechanics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-4 z 4

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