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    Wyświetlanie 1-3 z 3
    Tytuł:
    Preparation and cytological study of collagen/nano-hydroxyapatite/graphene oxide composites
    Autorzy:
    Wang, J.
    Wang, Y.
    Liu, D.
    Yang, Q.
    Huang, C.
    Yang, C.
    Zhang, Q.
    Powiązania:
    https://bibliotekanauki.pl/articles/307450.pdf
    Data publikacji:
    2018
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    nanohydroksyapatyt
    tlenek grafitu
    mineralizacja
    kolagen
    nano-hydroxyapatite
    graphene oxide
    biomimetic mineralization
    collagen
    Opis:
    Biomimetic mineralized composite scaffolds are widely used as natural bone substitute materials in tissue engineering by inducing and assembling bonelike apatite. In this study, the single lamellar structure of graphene oxide (GO) powder was prepared via an improved Hummers’ method. Methods: To better mimic natural bone, the collagen (COL)/Nano-hydroxyapatite (nHA)/graphene oxide (GO) composite material was prepared by simulated body fluid (SBF) method using COL/GO as a matrix template. Hydroxyapatite (HA) with calcium ion deficiency was achieved via biomimetic mineralization, and it had properties closer to those of natural bone than pure HA has. Results: The mineralized COL/nHA/GO composites exhibited loose porous structures, and the connectivity of the holes was good and thus beneficial to the exchange of nutrients and excreted metabolites. Conculsions: Antibacterial and MTT experiment confirmed that the COL/nHA/GO composite material had excellent antibacterial property and biocompatibility. Hence, these results strongly suggested the mineralized COL/nHA/GO composite is a good candidate biomaterial to be applied in bone tissue engineering.
    Źródło:
    Acta of Bioengineering and Biomechanics; 2018, 20, 4; 65-74
    1509-409X
    2450-6303
    Pojawia się w:
    Acta of Bioengineering and Biomechanics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Biomechanical simulation of needle insertion into cornea based on distortion energy failure criterion
    Autorzy:
    Su, P.
    Yang, Y.
    Huang, L.
    Powiązania:
    https://bibliotekanauki.pl/articles/306549.pdf
    Data publikacji:
    2016
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    rogówka
    biomechanika
    symulacja matematyczna
    cornea
    biomechanics
    insertion force
    suture
    mathematical simulation
    Opis:
    Purpose: This paper is mainly about biomechanical behavior of needle insertion into cornea, and proposes a failure criterion to simulate the insertion process which has attracted considerable attention due to its importance for the minimally invasive treatment. Methods: In the process of needle insertion into cornea, tiny and complex insertion force is generated due to contact between needle and soft tissue. Based on the distortion energy theory, there is proposed a failure criterion of corneal material that can solve contact problem between rigid body and biological tissue in insertion simulation, where Cauchy stress of corneal material is the key to numerical calculation. A finite element model of in vivo cornea is built, and the cornea constrained by sclera is simplified to two layers containing epithelium and stroma. Considering the hyper-viscoelastic property of corneal material, insertion simulation is carried out. Results: By insertion experiment, the insertion force increases with insertion depth accompanying obvious fluctuations. Different insertion forces are generated at different speeds. The punctured locations are obvious in the force-displacement curves. The results of insertion simulation are generally consistent with experimental data. Maps of von Mises stress reflect the tissue injury of the cornea during insertion process, and punctured status corresponds to the point in the curves. Conclusions: The ability of this study to reproduce the behavior of needle insertion into cornea opens a promising perspective for the control of robotic surgery operation as well as the real-time simulation of corneal suture surgery.
    Źródło:
    Acta of Bioengineering and Biomechanics; 2016, 18, 1; 65-75
    1509-409X
    2450-6303
    Pojawia się w:
    Acta of Bioengineering and Biomechanics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Analysis of the influence of the transducer and its coupling layer on round window stimulation
    Autorzy:
    Liu, H.
    Xu, D.
    Yang, J.
    Yang, S.
    Cheng, G.
    Huang, X.
    Powiązania:
    https://bibliotekanauki.pl/articles/306655.pdf
    Data publikacji:
    2017
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    słuch
    stymulacja
    przetwornik
    RW
    FEM
    implantable middle ear hearing device
    round window stimulation
    transducer
    coupling layer
    finite element analysis
    Opis:
    Purpose: In this work, a finite element study is proposed to evaluate the effects of the transducer and its coupling layer on the performance of round window (RW) stimulation. Methods: Based on a set of micro-computer tomography images of a healthy adult’s right ear and reverse engineering technique, a coupled finite-element model of the human ear and the transducer was constructed and verified. Then, the effect of the cross-section of the transducer, the elastic modulus of the coupling layer, the mass of the transducer, and the preload of the transducer were studied. Results: The increase of the transducer’s cross-section area deteriorates the RW stimulation, especially at the lower frequencies. This adverse effect of the cross-section area’s increase of the transducer can be reduced by adding a coupling layer between the transducer and the RW. However, the coupling layer’s improvement on the RW stimulation is reduced with the increase of its elastic modulus. Moreover, the mass loading of the transducer decreases the RW stimulation’s performance mainly at higher frequencies and applying a static preload on the transducer enhances its hearing compensating performance at higher frequencies. Conclusions: The influence of the transducer’s mass, the mass of the transducer, the applied static preload and the properties of the coupling layer must be taken into account in the design of the RW stimulation type implantable middle ear hearing device.
    Źródło:
    Acta of Bioengineering and Biomechanics; 2017, 19, 2; 103-111
    1509-409X
    2450-6303
    Pojawia się w:
    Acta of Bioengineering and Biomechanics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-3 z 3

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