- Tytuł:
- Main Pro-Apoptotic Member of Bcl-2 Family Proteins – Bax
- Autorzy:
-
Żołnierczyk, Jolanta Dominika
Kiliańska, Zofia Maria - Powiązania:
- https://bibliotekanauki.pl/articles/764983.pdf
- Data publikacji:
- 2010
- Wydawca:
- Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
- Tematy:
-
apoptosis
Bcl-2 family
Bax
apoptosis mitochondrial pathway - Opis:
- Programmed cell death (apoptosis) plays a vital role in the regulation of cellular homeostasis. Because of apoptosis fundamental importance, this process is highly regulated. One important set of factors involved in apoptosis regulation is the Bcl-2 family proteins. Bcl-2 family members form a complex regulatory network that controls cell survival and death in response to different physiological and pathological signals. This family includes both pro- and anti-apoptotic members, and Bax protein (Mol wt 21 kDa) is a major pro-apoptotic factor with multifunctional activity. This review summarizes new data about the main representative of Bcl-2 family – Bax, its structure and mechanism(s) by which this protein modulates apoptosis.
- Źródło:
-
Acta Universitatis Lodziensis. Folia Biologica et Oecologica; 2010, 6; 5-32
1730-2366
2083-8484 - Pojawia się w:
- Acta Universitatis Lodziensis. Folia Biologica et Oecologica
- Dostawca treści:
- Biblioteka Nauki
Artykuł