- Tytuł:
- Actinomycin D as an Epimutagen in Protists
- Autorzy:
-
Uspenskaya, Zoya I.
Yudin, Alexander L. - Powiązania:
- https://bibliotekanauki.pl/articles/52376322.pdf
- Data publikacji:
- 2017
- Wydawca:
- Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego
- Tematy:
-
actinomycin D
Amoeba proteus
Dileptus anser
epigenetic variation
epimutagen
inheritable destabilization of characters - Opis:
- A previously unrecorded property of actinomycin D, a well-known antibiotic, was discovered in the course of long-term genetic research on the amoeba Amoeba proteus and the ciliate Dileptus anser. In these protists actinomycin D can induce an unusual type of hereditary variation, which we refer to as the inheritable destabilization of characters. A number of features indicate that this variation is epigenetic, that is, not caused by mutations in the DNA. Therefore, actinomycin D may be considered as an inducer of epigenetic inheritable changes, in other words, as an epimutagen.
- Źródło:
-
Acta Protozoologica; 2017, 56, 3; 139-147
0065-1583
1689-0027 - Pojawia się w:
- Acta Protozoologica
- Dostawca treści:
- Biblioteka Nauki
Artykuł