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    Wyświetlanie 1-3 z 3
    Tytuł:
    IMPACT OF EXCIPIENTS ON PHARMACEUTICAL AVAILABILITY OF FOLIC ACID FROM TABLETS
    Autorzy:
    Ostróżka-Cieślik, Aneta
    Dolińska, Barbara
    Ryszka, Florian
    Powiązania:
    https://bibliotekanauki.pl/articles/895567.pdf
    Data publikacji:
    2018-08-31
    Wydawca:
    Polskie Towarzystwo Farmaceutyczne
    Tematy:
    folic acid
    dietary supplements
    dissolution testing
    Opis:
    The impact of excipients contained in individual formulations on the pharmaceutical availability of folic acid was investigated. The release rate of the active substance and the disintegration time of the tablets were analysed. It has been found that in the presence of sorbitol, glucose and starch, 100% of folic acid is released within 60 minutes, and in the presence of lactose and starch - 95%, and the release rates for them are 0.0717 min-1 and 0.0555 min-1 respectively.
    Źródło:
    Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 4; 959-963
    0001-6837
    2353-5288
    Pojawia się w:
    Acta Poloniae Pharmaceutica - Drug Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    EVALUATION OF NUTRITIONAL AND MEDICINAL PROPERTIES OF BACOPA MONNIERI BIOMASS AND PREPARATIONS
    Autorzy:
    Muszyńska, Bożena
    krakowska, Agata
    Lazur, Jan
    Szewczyk, Agnieszka
    Opoka, Włodzimierz
    Powiązania:
    https://bibliotekanauki.pl/articles/895242.pdf
    Data publikacji:
    2018-12-31
    Wydawca:
    Polskie Towarzystwo Farmaceutyczne
    Tematy:
    dietary supplements
    phenolic compounds
    Bacopa monnieri
    artificial digestive juices
    bioelements
    Opis:
    Bacopa monnieri (Scrophulariaceae) is a well-known plant and has been used by humans for several thousand years. In traditional Hindu medicine, it is one of the most important medicinal plants. The aim of the work was to determine the content of Fe, Mg, and Zn and selected organic compounds before and after extraction into the artificial digestive juices obtained from preparations containing B. monnieri. Commercial preparations in the form of tablets and capsules and B. monnieri shoot cultures were used in the experiment. The metal content in the considered mineralized samples was analyzed by atomic absorption spectrometry and organic compounds by RP-HPLC method. The maximum measured content of the metals released into the digestive juices was as follows: Fe – 32.85; Mg – 367.51; and Zn – 16.41 mg/100 g of the preparation. The existing research shows that metals are best released into the artificial digestive juices from the B. monnieri shoot cultures, and least efficiently from the commercial preparations available in the form of tablets. The phenolic compounds analyzed in the methanol extracts and the extracts of the artificial digestive juices were as follows: protocatechuic acid, p-hydroxybenzoic acid, neochlorogenic acid, chlorogenic acid, isochlorogenic acid, caffeic acid, ferulic acid, cynaroside, trifolin, and luteolin. Bacoside A was only determined in the extracts from the B. monnieri shoot cultures. The experimental results revealed that B. monnieri distributed in the form of tablets did not break down in the artificial digestive juices during the considered time intervals.
    Źródło:
    Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 6; 1353-1361
    0001-6837
    2353-5288
    Pojawia się w:
    Acta Poloniae Pharmaceutica - Drug Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    ANALYSIS OF IRON CONTENT IN FOOD SUPPLEMENTS IN RELATION TO THE SAFETY OF THEIR USE
    Autorzy:
    Surowiecka, Joanna M.
    Olczyk, Pawel
    Ivanova, Diana
    Kiselova-Kaneva:, Yoana
    Komosińska-Vassev, Katarzyna
    Powiązania:
    https://bibliotekanauki.pl/articles/895334.pdf
    Data publikacji:
    2020-04-29
    Wydawca:
    Polskie Towarzystwo Farmaceutyczne
    Tematy:
    food safety
    pregnant women
    iron
    dietary supplements
    iron deficiency
    microwave mineralization
    Opis:
    Objective of the study was to test dietary supplements available on the European market with regard to their iron content. Twenty-nine vitamin and mineral supplements were investigated, with additional assessment of their mass homogeneity. Iron was determined by means of the AAS1 method following microwave mineralization of particular samples. Findings were compared to iron contents declared by producers. Tested supplements were analysed with regard to the ratio between the amount of iron supplied to the body and the RDA2 for adults and pregnant women, as well as in view of the number of preparation pieces required to be taken in in order to ensure the RDA in the groups included in the research. All preparations were characterised by high mass homogeneity. The iron content determined in the supplements was different from the values indicated by the producers on the packages. Four supplements did not meet the European requirements concerning acceptable limits of nutrient tolerance stated on the labels. Tolerance for iron value in food supplements indicated by producers on packages varied from RDAs for the studied groups. The dosage recommended by the producer was mostly different from the dosage necessary to meet the requirements for iron RDA in the studied groups.
    Źródło:
    Acta Poloniae Pharmaceutica - Drug Research; 2020, 77, 2; 229-239
    0001-6837
    2353-5288
    Pojawia się w:
    Acta Poloniae Pharmaceutica - Drug Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-3 z 3

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