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    Wyświetlanie 1-2 z 2
    Tytuł:
    DIPSACUS FULLONUM L. LEAVES AND ROOTS - IDENTIFICATION OF THE COMPONENTS OF THE ESSENTIAL OILS AND ALPHA-AMYLASE INHIBITORY ACTIVITIES OF METHANOLIC EXTRACTS
    Autorzy:
    Witkowska-Banaszczak, Ewa
    Powiązania:
    https://bibliotekanauki.pl/articles/895320.pdf
    Data publikacji:
    2018-08-31
    Wydawca:
    Polskie Towarzystwo Farmaceutyczne
    Tematy:
    essential oil composition
    methanolic extract
    alpha-amylase inhibition
    Opis:
    Abstract: Dipsacus fullonum L. syn. D. sylvestris is a biennial plant from the Dipsacaceae family. It grows in Europe, North Africa and Asia Minor. It has been used in folk medicine mainly to treat Lyme disease. This study was undertaken to identify and compare the components of the essential oils from dried and fresh roots, which are usually applied as medicinal agents, as well as those of the essential oils from dried and fresh leaves, used less frequently. The essential oils from the Dipsacus fullonum leaves and roots were analysed by the GC and GC-MS analysis. 18 components were identified in the essential oil from the fresh leaves, whereas 37 were recognised in the oil from the dried leaves; 10 components were identified in the essential oil from the fresh roots and 40 in that from the dried roots. Phytol was the main component in the essential oil from the leaves, whereas n-hexadecanoic acid was predominant in the roots. The α -amylase inhibition has been proven for methanolic extracts of D. fullonum leaves and roots. The strongest activity was demonstrated by the extract from fresh leaves of D. fullonum and showed an effect about one hundred times weaker than acarbose.
    Źródło:
    Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 4; 951-957
    0001-6837
    2353-5288
    Pojawia się w:
    Acta Poloniae Pharmaceutica - Drug Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Chemical profile and antibacterial activity of essential oils from leaves and fruits of Gaultheria procumbens L. cultivated in Poland
    Autorzy:
    Magiera, Anna
    Sienkiewicz, Monika
    Olszewska, Monika
    Kicel, Agnieszka
    Michel, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/895472.pdf
    Data publikacji:
    2019-02-28
    Wydawca:
    Polskie Towarzystwo Farmaceutyczne
    Tematy:
    essential oil
    antibacterial activity
    chemical composition
    methyl salicylate
    Gaultheria procumbens L
    GC-FID/MS analysis
    Opis:
    Essential oils (EOs) of Gaultheria procumbens were obtained by hydrodistillation with the yield of 1.30% ± 0.05 (v/dw) for leaves and 2.68% ± 0.08 (v/dw) for fruits. The GC-FID/MS analysis led to the identification of 64 volatile components, among which 27 were found in leaf EO, 49 in fruit EO, and 59 analytes were detected for the first time in G. procumbens. Methyl salicylate, which is known as a potent anti-inflammatory agent, was the dominant component making up to 97.5% and 99.8% of the total fruit and leaf EOs, respectively. The remaining volatiles of the leaves included mainly monoterpenes (α-pinene, β-pinene, limonene), methyl-o-anisate, massoilactone, spiro[4,5]decane-1-one, and aliphatic alcohols (heptan-2-ol, octan-1-ol), while the fruit EO contained apart from the dominant aliphatic and aromatic alcohols (benzyl alcohol, heptan-2-ol, p-cymen-7-ol) also carboxylic acids (3-hydroxyphenylacetic acid, heptanoic acid, octanoic acid) and aldehydes (hexanal, furfural, pent-4-enal). The antibacterial activity of the EOs was evaluated using a microdilution broth method against twelve reference strains, as well as clinical and environmental isolates. Differences between activity parameters of both EOs were not statistically significant (p > 0.05) for most tested bacteria. On the other hand, both EOs were significantly more effective against Gram-negative (MIC, 8.2-10.0 mg/mL) than Gram-positive bacteria (MIC, 13.5-16.7 mg/mL). Leaves and especially fruits of G. procumbens cultivated in Poland were proved valuable sources of methyl salicylate-rich EOs of moderate antibacterial activity, which, therefore, could partly explain the traditional use of the plant materials and the EOs in the treatment of bacterial infections-related inflammatory disorders.
    Źródło:
    Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 1; 93-102
    0001-6837
    2353-5288
    Pojawia się w:
    Acta Poloniae Pharmaceutica - Drug Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-2 z 2

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