Autor: Paszkiewicz, Anna - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Activity of partially purified UDP-N-acetyl-α-D-galacto- samine:polypeptide N-acetylgalactosaminyltransferase with different peptide acceptors
Autorzy:: Porowska, Halina
Paszkiewicz-Gadek, Anna
Gindzieński, Andrzej
Powiązania:: https://bibliotekanauki.pl/articles/1044518.pdf
Data publikacji:: 1999
Wydawca:: Polskie Towarzystwo Biochemiczne
Źródło:: Acta Biochimica Polonica; 1999, 46, 2; 365-370
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: The participation of ribosome-UDP-GalNAc complex in the initiation of protein glycosylation in vitro
Autorzy:: Paszkiewicz-Gadek, Anna
Porowska, Halina
Gindzieński, Andrzej
Powiązania:: https://bibliotekanauki.pl/articles/1044369.pdf
Data publikacji:: 2000
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: glycosylation
UDP-GalNAc-transferase
UDP-GalNAc
apomucin
ribosome
Opis:: The gastric epithelial cells ribosome-UDP-GalNAc complex is a donor of UDP- GalNAc as the substrate for N-acetylgalactosaminyltransferase, which catalyse the transfer of GalNAc residue to the polypeptide, existing on polysomes. It was observed that the deglycosylated porcine mucin and synthetic peptide (PTSSPIST) can be also glycosylated with participation of N-acetylgalactosaminyltransferase and ribosome- UDP-GalNAc complex. The probability of the ribosome-UDP-GalNAc complex as an intermediate in the O-glycosylation is considered.
Źródło:: Acta Biochimica Polonica; 2000, 47, 2; 421-426
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: The participation of ribosomes in protein glycosylation. Interaction of the ribosome-UDP-N-acetyl-glucosamine complex with dolichol phosphate
Autorzy:: Paszkiewicz-Gadek, Anna
Porowska, Halina
Gałasiński, Władysław
Powiązania:: https://bibliotekanauki.pl/articles/1045571.pdf
Data publikacji:: 1992
Wydawca:: Polskie Towarzystwo Biochemiczne
Źródło:: Acta Biochimica Polonica; 1992, 39, 3; 251-264
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Vaccinium myrtillus leaves and Frangula alnus bark derived extracts as potential antistaphylococcal agents
Autorzy:: Sadowska, Beata
Paszkiewicz, Małgorzata
Podsędek, Anna
Redzynia, Małgorzata
Różalska, Barbara
Powiązania:: https://bibliotekanauki.pl/articles/1039358.pdf
Data publikacji:: 2014
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: phytocompounds
antimicrobial activity
synergism with antibiotics
biocompatibility index
Opis:: Due to constantly increasing antibiotic resistance of pathogens and participation of the biofilms they make in various types of infections, a development of alternative therapeutic strategies becomes an urgent need. Taking advantage of the biological activity of plant-derived compounds can solve this problem. In this study antimicrobial, including those synergistic with classic antibiotics, and cytotoxic properties of newly-obtained extracts from Vaccinium myrtillus leaves (VLE) and Frangula alnus bark (FBE) were evaluated. Both tested extracts exhibited relevant antistaphylococcal activity (MIC range 0.75-1.5 mg/mL) accompanied by a relativly low cytotoxic effect on mammalian cells (BI > 1). Phytochemical analysis of the extracts tested showed a high total content of phenolic compounds with the predominance of hydroxycinnamic acids in VLE and hydroxybenzoic acids and flavanols in FBE. Widely described in the literature antimicrobial properties of phenolics were probably connected with the biological activity of the extracts tested. We also report that the presence of VLE or FBE at sub-MIC concentrations enhances biocidal potential of vancomycin and linezolid. Therefore, we are considering a possibility of an alternative therapy for local infections caused by S. aureus by combining classic antibiotics with plant-derived extracts.
Źródło:: Acta Biochimica Polonica; 2014, 61, 1; 163-169
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: Usefulness of real-time PCR in long-term follow-up of follicular lymphoma patients
Autorzy:: Tysarowski, Andrzej
Fabisiewicz, Anna
Paszkiewicz-Kozik, Ewa
Kulik, Jadwiga
Walewski, Jan
Siedlecki, Janusz
Powiązania:: https://bibliotekanauki.pl/articles/1041125.pdf
Data publikacji:: 2007
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: real-time PCR
follicular lymphoma
minimal residual disease
molecular remission
Opis:: The aim of this study was to evaluate the usefulness of quantitative real-time PCR (RQ-PCR) for the monitoring of molecular remission in follicular lymphoma (FL) patients during long-term follow-up. RQ-PCR by the use of TaqMan® detection system is a sensitive tool to monitor minimal residual disease (MRD) in FL through amplification of the t(14;18) fusion gene during and post-therapy. In most cases the breakpoint region occurs within the major breakpoint region (MBR). Among 75 patients diagnosed with FL, cells harboring the fusion gene BCL2/JH were found in peripheral blood of 31 patients (41%). We further monitored 30 of these patients in a period varying from 6 months to 5 years by RQ-PCR. In our study the level indicating the possibility of the presence of MRD was established at more than five t(14;18)-positive cells in the background of 83000 normal cells. The results of this work also confirmed that the presence of MRD detected by RQ-PCR is an indication for careful observation of patients because of a higher risk of disease recurrence.
Źródło:: Acta Biochimica Polonica; 2007, 54, 1; 135-142
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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