Temat: protein phosphatase - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Interaction of maize (Zea mays) protein phosphatase 2A with tubulin
Autorzy:: Awotunde, Olubunmi
Lechward, Katarzyna
Krajewska, Katarzyna
Żołnierowicz, Stanisław
Muszyńska, Grażyna
Powiązania:: https://bibliotekanauki.pl/articles/1043655.pdf
Data publikacji:: 2003
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: protein phosphatase 2A
tubulin
protein-protein interaction
plant cytoskeleton organization
maize
Opis:: Immunological and biochemical evidence has been obtained for an interaction of maize protein phosphatase 2A (PP2A) holoenzyme with tubulin. Tubulin co-purifies with maize seedling PP2A. Affinity chromatography of the maize PP2A preparation on immobilized tubulin revealed two peaks of phosphorylase a phosphatase activity. In one of the peaks, the catalytic (C) and constant regulatory (A) subunits of PP2A were identified by Western blotting. The subunits (C and A) of PP2A were co-immunoprecipitated from maize seedlings homogenate by an anti-α-tubulin antibody. The interaction of plant PP2A with tubulin indicates a possible role of reversible protein phosphorylation in the dynamic structure of plant cytoskeleton.
Źródło:: Acta Biochimica Polonica; 2003, 50, 1; 131-138
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

Artykuł

Skocz do pozycji: 2.

Tytuł:: Protein phosphatase 2A: Variety of forms and diversity of functions
Autorzy:: Lechward, Katarzyna
Awotunde, Olubunmi
Świątek, Wojciech
Muszyńska, Grażyna
Powiązania:: https://bibliotekanauki.pl/articles/1044037.pdf
Data publikacji:: 2001
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: protein phosphatase 2A
signal transduction
protein-protein interactions
reversible phosphorylation
cell cycle
carcinogenesis.
Opis:: Protein phosphatase 2A (PP2A) comprises a diverse family of phosphoserine-and phosphothreonine-specific phosphatases present in all eukaryotic cells. All forms of PP2A contain a catalytic subunit (PP2Ac) which forms a stable complex with the structural subunit PR65/A. The heterodimer PP2Ac-PR65/A associates with regulatory proteins, termed variable subunits, in order to form trimeric holoenzymes attributed with distinct substrate specificity and targeted to different subcellular compartments. PP2Ac activity can be modulated by reversible phosphorylation on Tyr307 and methylation on C-terminal Leu309. Studies on PP2A have shown that this enzyme may be implicated in the regulation of metabolism, transcription, RNA splicing, translation, differentiation, cell cycle, oncogenic transformation and signal transduction.
Źródło:: Acta Biochimica Polonica; 2001, 48, 4; 921-933
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

Artykuł

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