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Tytuł:
The incidence of allergy to common allergens based on a retrospective analysis
Częstość występowania alergii na pospolite alergeny na podstawie analizy retrospektywnej
Autorzy:
Czarny-Działak, M.
Działak, M.
Wójcik, T.
Chmielowiec, B.
Chmielewski, J.P.
Powiązania:
https://bibliotekanauki.pl/articles/2048089.pdf
Data publikacji:
2021
Wydawca:
Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej
Tematy:
allergy
skin prick test
allergen
Opis:
Background. The aim of this work was to find out which of the aeroallergens most often cause positive skin prick tests in the population with allergic diseases. Depending on the type of allergens, exposure to them can aggravate asthma symptoms and cause allergic conjunctivitis and allergic rhinitis. Material and methods. A group of 100 people between 18 and 78 years of age were included in the study. The average age was 45.8 years. There were 34 men and 66 women in the group. All patients were allergy clinic patients. The results of point skin tests for the basic aeroallergen panel were analyzed in this study and summarized using descriptive statistics. Results. Sixty subjects had positive tests for dust mites. Most subjects were allergic to two allergens. Monovalent allergy was found in 10 subjects. Multivalent allergy was predominant, but tended to involve relatively few allergens. Conclusions. The results obtained may be due to year-round exposure to the house dust mite allergen. Prolonged allergen exposure translates into more frequent immune responses and greater clinical response of patients, which is manifested by allergic rhinitis and/or bronchial asthma or allergic conjunctivitis. Due to the small patient population studied, this subject requires further analysis.
Źródło:
Health Problems of Civilization; 2021, 15, 3; 164-172
2353-6942
2354-0265
Pojawia się w:
Health Problems of Civilization
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Suspicion of bovine tuberculosis in sheep in the Małopolskie Voivodeship (southern Poland)
Autorzy:
Didkowska, A.
Żmuda, P.
Orłowska, B.
Nowak, M.
Filip-Hutsch, K.
Cuper, K.
Krajewska-Wędzina, M.
Anusz, K.
Powiązania:
https://bibliotekanauki.pl/articles/16539333.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
bovine tuberculosis
dairy products
IGRA
sheep
tuberculin skin test
Opis:
Bovine tuberculosis (BTB) in sheep (Ovis aries) is caused by Mycobacterium bovis and Mycobacterium caprae. Even though sheep have been considered less sensitive to BTB than other ruminants, they have been subject to increasing numbers of tuberculosis cases and it has been suggested that they may act as a disease reservoir in some regions. Aim of the study: Following a report of tuberculous-like gross lesions (repeated cases of purulent or caseous lymphadenitis and a single case of serosal tubercles on the peritoneum) from veterinarians working in a slaughterhouse in the Małopolskie Voivodeship, southern Poland, the aim of this study was to conduct ante-mortem BTB diagnostics in three flocks with suspected BTB. The animals for testing were selected randomly from the flocks; a blood sample for interferon-γ release assay (IGRA) and a single tuberculin skin test (TST) was performed on each sheep. All TST results were negative. The IGRA result was positive in two ewes from the same flock (four and five years of age); these two sheep were tested microbiologically using Stonebrink and Löwenstein-Jensen media. No gross lesions suggesting BTB were observed, and the culture results were negative. Based on the positive IGRA results, together with its high specificity in sheep, and the potential risk to humans posed by consuming local unpasteurized dairy products, we recommend introducing serological BTB screening in sheep from this area, and subjecting the positive results to confirmation by culture.
Źródło:
Polish Journal of Veterinary Sciences; 2022, 25, 3; 469-473
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The balance between pro- and anti-inflammatory cytokines in the immune responses to BCG and DTwP vaccines
Autorzy:
Druszczynska, Magdalena
Kowalewicz-Kulbat, Magdalena
Maszewska, Agnieszka
Rudnicka, Karolina
Szpakowski, Piotr
Wawrocki, Sebastian
Wlodarczyk, Marcin
Rudnicka, Wiesława
Powiązania:
https://bibliotekanauki.pl/articles/1038943.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
BCG
pertussis
IFN-gamma
IL-10
tuberculin skin test
dendritic cells
Opis:
Bacillus Calmette-Guérin (BCG) and pertussis vaccines have been found to be insufficient and their further improvement is required. In order to develop improved vaccines, a better understanding of the main pathways involved in the host's protective immunity to the pathogens is crucial. We address the question as to whether the balance between pro- and anti-inflammatory cytokine production might affect the host responses to BCG and diphtheria-tetanus toxoids-whole cell pertussis (DTwP) vaccines. The study population consisted of 118 healthy people, age range 18-30 years, who had been subjected to BCG and DTwP vaccination according to the state policy. Tuberculin skin testing (TST) revealed a delayed type hypersensitivity (DTH) to PPD (purified protein derivative) in 53% volunteers. The variability in development of the BCG-driven DTH to tuberculin prompted us to address a question as to whether Th1/Th2 polarization is involved in the lack of skin responsiveness to PPD. PPD-stimulated blood lymphocytes from TST+ participants produced significantly more IFN-γ and less IL-10 than lymphocytes from TST- volunteers. However, TST- volunteers' sera contained more anti-pertussis IgG but not anti-diphtheria toxin IgG. Mycobacterial antigens and particularly PPD induced a higher expression of HLA-DR and co-stimulatory CD80 receptors on DCs from TST+ than TST- participants. BCG but not PPD pulsed DCs from TST- volunteers produced significantly more IL-10. Mycobacterial antigen stimulated DCs from TST+ volunteers induced a more intense IFN-γ production in co-cultures with autologous lymphocytes than the cells from TST- participants. Differences among the types of dendritic cell activities contribute to development of tuberculin reactivity in BCG vaccinated volunteers.
Źródło:
Acta Biochimica Polonica; 2015, 62, 4; 913-921
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The results of intradermal skin tests (IDST) in dogs with atopic dermatitis from the Lublin voivodship
Autorzy:
Taszkun, I.
Powiązania:
https://bibliotekanauki.pl/articles/32510.pdf
Data publikacji:
2011
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
aeroallergen
Lublin voivodship
allergen
atopic dermatitis
dog
intradermal test
skin test
skin disease
animal disease
allergic disease
canine atopic dermatitis
pollen allergen
Opis:
The purpose of this study was to assess the positive immediate reactions received from intradermal skin tests (IDST) which confirmed the presence of IgE-dependent hypersensitivity in dogs with atopic dermatitis, which were patients of the Dermatology Consulting Section at the University of Life Sciences in Lublin between 2007 and 2009. Intradermal skin tests were performed on 142 dogs (72 females and 70 males) from the Lublin voivodeship of different breeds ranging in age from 1 to 6 years (average 2.8 years). The allergen set used in this study was the Artuvetrin Test (ARTU Biologicals Europe B.V, Holland). The owners of 84 dogs observed the presence of skin lesions all year round regardless of season, while 58 dog owners noted them only in spring and summer. Most immediate positive reactions were ascertained from mite allergens (70.61%), fewer from pollen allergens (19.55%), and the fewest from animal (4.15%) and mould allergens (1.66%). Immediate positive reactions for a flea allergen (4.03% of all positive reactions) were also ascertained. In 98.6% of dogs polysensitization was found.
Źródło:
Polish Journal of Veterinary Sciences; 2011, 14, 1
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Respiratory health problems in adolescents living near main roads in the Upper Silesian industrial zone, Poland
Autorzy:
Skrzypek, Michał
Kowalska, Małgorzata
Kasznia-Kocot, Joanna
Czech, Elżbieta M.
Niewiadomska, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/2161966.pdf
Data publikacji:
2019-07-15
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
lung volume measurements
respiratory diseases
adolescents
skin prick test
transportation
vehicles
Opis:
Objectives This study explores the association between self-reported exposure to traffic-related air pollution and respiratory health symptoms, as well as lung functions and skin prick tests in adolescents living in the vicinity of main roads. Material and Methods The data in the study were acquired using a cross-sectional study conducted between 2004–2005 in Chorzów (Silesia, Poland) among adolescents (N = 936) aged 13–15 years, attending junior high schools. Adverse respiratory health symptoms and exposure to traffic-related air pollution were determined on the basis of a questionnaire. Moreover, all children underwent spirometry and skin prick tests. Multivariable logistic regression with multiple imputation for missing data was used to assess the prevalence of adverse respiratory symptoms in relation to self-reported exposure to traffic-related air pollution, adjusted for socioeconomic and environmental factors. Results Among respiratory tract diseases, asthma and allergic rhinitis associations were statistically significant (OR = 2.16, 95% CI: 1.12–4.15 and OR = 1.69, 95% CI: 1.08–2.64, respectively). Likewise, among respiratory disorders, statistically significant associations were found in the case of wheezes and dyspnea attack (OR = 1.58, 95% CI: 1.10–2.26 and OR = 2.39, 95% CI: 1.56–3.66, respectively), with respect to the vicinity of the main road. Living in the area with high traffic intensity was statistically significantly associated with a higher prevalence of asthma and wheezes (OR = 2.31, 95% CI: 1.22–4.39 and 1.48, 95% CI: 1.09–2.01, respectively). The results obtained did not confirm the relationship between the adopted way of exposure to traffic-related air pollution and lung function indices or skin prick tests. Conclusions Results of the study suggest that children living in the area with intense traffic are more likely to develop respiratory disorders. Moreover, the vicinity of a main road as well as traffic intensity could be suitable in assessing the relationship between road transport and potential health problems among exposed inhabitants. Int J Occup Med Environ Health. 2019;32(4):553–67
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2019, 32, 4; 553-567
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Molecular profile of sensitization in subjects with short occupational exposure to latex
Autorzy:
Lamberti, Monica
Buonanno, Rosaria
Ritonnaro, Chiara
Giovane, Giancarlo
Crispino, Vincenzo
Feola, Antonia
Medici, Nicola
Sannolo, Nicola
Di Carlo, Angelina
Di Domenico, Marina
Powiązania:
https://bibliotekanauki.pl/articles/2177165.pdf
Data publikacji:
2015-07-17
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
occupational exposure
ImmunoCAP
natural rubber latex
skin prick test
contact dermatitis
gloves
Opis:
Objectives We examined the prevalence of latex allergy in subjects with occupational exposure to latex allergens for less than 5 years, determining the disease spectrum in symptomatic workers. We identified the most frequent molecular allergens by Immuno- CAP (ICAP), correlating the findings with skin prick test (SPT) results. Material and Methods Seven hundred twenty-three healthcare students using latex gloves on a regular basis were invited to participate in a baseline questionnaire screening. An ICAP serum test was performed only when a possible latex allergy was indicated by the questionnaire. Results The total number of participants responding to the baseline survey was 619. Glove-related symptoms were indicated by 4% (N = 25) of the students. The most common symptom was contact dermatitis (N = 18, 72%). In 12 subjects, ICAP revealed a real sensitization to latex, with a recombinant latex allergen profile showing a high frequency for rHev b 6.01 specific immunoglobulin E (sIgE) (N = 9, 67%). In these individuals, skin symptoms were more prevalent than other types (88%). Conclusions The combined positivity for rHev b 6.01, rHev 8 and rHev b 5 determined by ICAP identified 92% of latex-allergic subjects with short-term exposure to latex.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2015, 28, 5; 841-848
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Increased risk of horse sensitization in southwestern Iranian horse riders
Autorzy:
Moghtaderi, Mozhgan
Farjadian, Shirin
Hosseini, Zeynab
Raayat, Alireza
Powiązania:
https://bibliotekanauki.pl/articles/2177224.pdf
Data publikacji:
2015-07-01
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
lung function
skin prick test
horse rider
horse allergen
animal allergy
IgE
Opis:
Objectives The aim of this study has been to investigate the frequency of sensitization to horse allergens and clinical symptoms in horse riders. Material and Methods A total of 42 horse riders and 50 healthy individuals were examined by means of skin prick tests for a panel of horse and common animal allergens, and pulmonary function tests were done by spirometry. Results The rate of sensitization to horse allergens was 31% as proven by the skin prick test in horse riders whereas horse sensitization was not seen in the control group. Occupational allergy symptoms were reported by 19 horse riders. Two horse riders with no history of clinical symptoms showed positive skin reactions to horse allergens. Conclusions To decrease the high risk of occupational sensitization among horse riders, workplace conditions should be improved to reduce the load of airborne horse allergens.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2015, 28, 5; 909-913
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Meteorological and agricultural effects on airborne Alternaria and Cladosporium spores and clinical aspects in Valladolid [Spain]
Autorzy:
Reyes, E S
de la Cruz, D.R.
Merino, E.S.
Sanchez, J.S.
Powiązania:
https://bibliotekanauki.pl/articles/51010.pdf
Data publikacji:
2009
Wydawca:
Instytut Medycyny Wsi
Tematy:
Alternaria
Cladosporium
spore
meteorological effect
agricultural effect
maximum concentration
temperature
skin test reaction
clinical aspect
Spain
allergy
human disease
Źródło:
Annals of Agricultural and Environmental Medicine; 2009, 16, 1; 53-61
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ocena alergicznego nieżytu nosa u nurków za pomocą testu skin prick
Utilising a skin prick test for the determination of the presence of allergic rhinitis in divers
Autorzy:
Olszański, R.
Dąbrowiecki, Z.
Niewiedział, D.
Gadomski, K.
Zieliński, E.
Powiązania:
https://bibliotekanauki.pl/articles/1359652.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Medycyny i Techniki Hiperbarycznej
Tematy:
nurkowanie
Skin Prick Test
alergiczny nieżyt nosa
nurkowie
scuba diving
allergic rhinitis
divers
Opis:
Alergiczny nieżyt nosa występuje w różnych regionach świata od 10 do 40% populacji. Test skin prick jest „złotym standardem” do wykrywania chorób alergicznych typu I według klasyfikacji Gella i Coombsa, w której pośredniczy IgE. Badania za pomocą testów Skin Prick wykonano u 60 nurków w wieku od 30 do 40 roku życia. Do badania zastosowano następujące testy powietrznopochodne: pyłki drzew, traw, zbóż, chwastów, białka roztoczy kurzu domowego, sierść i naskórek zwierząt oraz grzyby pleśniowe. Na podstawie wywiadu i dodatniego testu skin prick u 17 nurków stwierdzono alergiczny nieżyt nosa. Wnioski: 1. Alergiczny nieżyt nosa może powodować problemy zdrowotne u nurków i być przyczyną wypadków nurkowych. 2. Zastosowanie testu Skin Prick podczas kwalifikacji zdrowotnej w Wojskowej Komisji Morsko-Lekarskiej, pozwoliłoby wykluczyć kandydatów na nurków chorujących na alergię.
Allergic rhinitis occurs in various regions of the world and affects from 10 to 40% of the population. The skin prick test is the "gold standard" for the detection of type I allergic diseases according to the Gella and Coombs classification, which is mediated by IgE. For our experiment, skin prick tests were performed on 60 divers aged between 30 and 40 years of age. The following tests for airborne allergens were used: tests for pollen from trees, grasses, cereals, weeds, proteins from house dust mites, animal hair and epidermis, and moulds. On the basis of an interview and a positive skin prick test allergic rhinitis was diagnosed in 17 divers. Conclusions: 1. Allergic rhinitis can cause health problems in divers and be the cause of diving accidents. 2. The application of the skin prick test during the health qualification in the Military Maritime Health Commission, would allow the exclusion of diver candidates suffering from allergies.
Źródło:
Polish Hyperbaric Research; 2018, 4(65); 49-54
1734-7009
2084-0535
Pojawia się w:
Polish Hyperbaric Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Regional importance of Alnus pollen as an aeroallergen: a comparative study of Alnus pollen counts from Worcester [UK] and Poznan [Poland]
Autorzy:
Smith, M
Emberlin, J.
Stach, A.
Czarnecka-Operacz, M.
Jenerowicz, D.
Silny, W.
Powiązania:
https://bibliotekanauki.pl/articles/50630.pdf
Data publikacji:
2007
Wydawca:
Instytut Medycyny Wsi
Tematy:
Worcester
human disease
pollen
pollen grain
skin risk test
allergy
Poznan city
Europe
Alnus
allergen
Opis:
Daily average Alnus pollen counts (1996-2005) from Worcester (UK) and Poznań (Poland) were examined with the aim of assessing the regional importance of Alnus pollen as an aeroallergen. The average number of Alnus pollen grains recorded annually at Poznań was more than 2.5 times that of Worcester. Furthermore, daily average Alnus pollen counts exceeded the thresholds of 100, 500 and 1,000 grains/m3 more times at Poznań than Worcester. Skin prick test results (1996-2005) and allergen-specifi c IgE (asIgE) measurements using the CAP (Pharmacia) system (2002-2005), were supplied by the Allergic Diseases Diagnostic Centre in Poznań. The annual number of positive skin prick tests to Alnus pollen allergens was signifi cantly related (p<0.05) to seasonal variations in the magnitude of the Alnus pollen catch recorded at Poznań (r=0.70). The symptoms of patients with positive skin prick tests to Alnus pollen allergens were: 51% pollinosis, 43% atopic dermatitis, 4% asthma, 1% chronic urticaria and 1% eczema. On a scale of 0-6, 20.5% of patients examined for serum asIgE in relation to Alnus pollen allergens had asIgE measurements in classes 5 and 6. Alnus pollen is generally considered to be mildly allergenic. However, the amount of Alnus pollen released into the atmosphere in places such as Poznań may increase its impact on the population and make it one of the more important aeroallergens present.
Źródło:
Annals of Agricultural and Environmental Medicine; 2007, 14, 1
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
High prevalence of immunoglobulin E [IgE] sensitization among sisal [Agave sisalana] processing workers in Tanzania
Autorzy:
Kayumba, A V
Van-Do, T.
Florvaag, E.
Bratveit, M.
Baste, V.
Mashalla, Y.
Eduard, W.
Moen, B.E.
Powiązania:
https://bibliotekanauki.pl/articles/51120.pdf
Data publikacji:
2008
Wydawca:
Instytut Medycyny Wsi
Tematy:
skin prick test
sisal processing
sisal
Tanzania
total immunoglobulin E
sensitization
allergy
immunoglobulin E
respiratory symptom
Agave sisalana
Źródło:
Annals of Agricultural and Environmental Medicine; 2008, 15, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Skin and toe resistance mobilisation of pile during laboratory static load test
Autorzy:
Meyer, Z.
Żarkiewicz, K.
Powiązania:
https://bibliotekanauki.pl/articles/178958.pdf
Data publikacji:
2018
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
pile
static load test
skin friction
toe resistance
Opis:
This article shows the mathematical method to determine the lateral stress on the shaft and toe resistance of pile using the new approach. The method was originally invented by Meyer and Kowalow for the static load test. The approximation curve was used for the estimation of both settlement curve and toe resistance curve of the pile. The load applied at the head of the pile is balanced by the sum of two components: the resistance under the toe of the pile and the skin friction. Therefore, the settlement curve is compilation of two factors: the skin friction curve and the resistance under toe curve. The analysis was based on the verification of the methods using laboratory experiments, that is, static load tests. The results of the research allowed to determine the relationship between parameters of the Meyer-Kowalow curve. On the basis of the relationships, it was possible to determine the skin friction and the toe resistance of the pile. Mathematical analysis of curve parameters allowed to determine the influence of the toe resistance on the settlement.
Źródło:
Studia Geotechnica et Mechanica; 2018, 40, 1; 1-5
0137-6365
2083-831X
Pojawia się w:
Studia Geotechnica et Mechanica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Methods for evaluation of “in situ” coal permeability in underground coal mines using hydrodynamic test data
Metody określania przepuszczalności in situ w warunkach kopalnianych na podstawie wyników testów hydrodynamicznych
Autorzy:
Szpunar, T.
Budak, P.
Powiązania:
https://bibliotekanauki.pl/articles/1835239.pdf
Data publikacji:
2018
Wydawca:
Instytut Nafty i Gazu - Państwowy Instytut Badawczy
Tematy:
permeability
skin effect
coal seam
hydrodynamic test
slug test
horizontal drainage well
compressed air
przepuszczalność
skin-efekt
pokład węgla
test hydrodynamiczny
poziomy otwór drenażowy
sprężone powietrze
Opis:
The paper presents methods for in situ evaluation of coal permeability paying special attention to methods invented in the Oil and Gas Institute – National Research Institute (INiG – PIB). Included are: − a slug test method and alternative interpretation of slug test data using procedure devised in INiG – PIB, − a method which uses injection of water with a constant flow rate into a horizontal drainage well and accounts for the three dimensional flow (invented in INiG – PIB), − a method which uses air pressure decay in an isolated segment of a horizontal/vertical well to calculate permeability and skin effect (invented in INiG – PIB).
W artykule zaproponowano szereg metod przystosowanych do użytku w warunkach kopalnianych do określania przepuszczalności in situ węgli. Szczególną uwagę poświęcono metodzie interpretacji danych slug testu opracowanej w Instytucie Nafty i Gazu – Państwowym Instytucie Badawczym (INiG – PIB) oraz metodom zatłaczania wody do drenażowego odwiertu poziomego przy utrzymywaniu stałego wydatku tłoczenia uwzględniającym przepływ sferyczny, jak również metodzie interpretacji przebiegu spadku ciśnienia gazu w izolowanym odcinku otworu drenażowego wykorzystującej urządzenie opracowane w Głównym Instytucie Górnictwa (GIG). Wszystkie wymienione metody opracowano w INiG – PIB.
Źródło:
Nafta-Gaz; 2018, 74, 6; 443-450
0867-8871
Pojawia się w:
Nafta-Gaz
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Static load test curve analysis based on soil field investigations
Autorzy:
Siemaszko, P.
Meyer, Z.
Powiązania:
https://bibliotekanauki.pl/articles/202201.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
static pile test
skin friction
static load test curve
soil characteristics
badanie statyczne
obciążenie
cechy gleb
Opis:
This paper expands the M-K curve theory with examples of the most commonly mentioned pile-soil mechanics behaviours in the literature and their corresponding κ 2 variations. A brief introduction shows the history of the Meyer-Kowalow theory and its basic assumptions. This is followed by the relationship between in situ investigation CPT results, with parameters C1, C2, Ct used to approximate the load-settlement curve according to the M-K theory. The Meyer-Kowalow curve satisfies asymptotic behaviour for small loads, where linear theory applies, and for limit loads, when pile displacement is out of control. Essential in the description are constant parameters C, which refer to the aggregated Winklers modulus, Ngr limit loads and k, which is crucial for static load test results. For this reason, the authors sought to calculate the κ value based upon soil mechanics principles. This article shows methods for checking statistical mathematical calculations, published earlier by Meyer using CPT investigations. It presents real case calculations and directions for future planned research.
Źródło:
Bulletin of the Polish Academy of Sciences. Technical Sciences; 2019, 67, 2; 329-337
0239-7528
Pojawia się w:
Bulletin of the Polish Academy of Sciences. Technical Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Atopic eczema: genetics or environment?
Autorzy:
Wuthrich, B
Cozzio, A.
Roll, A.
Senti, G.
Kundig, T.
Schmid-Grendelmeier, P.
Powiązania:
https://bibliotekanauki.pl/articles/49593.pdf
Data publikacji:
2007
Wydawca:
Instytut Medycyny Wsi
Tematy:
inflammatory skin disease
environmental factor
food
atopy patch test
non-atopic eczema
Staphylococcus aureus
contact allergen
chronic disease
human disease
genetic condition
therapy
Malassezia sympodialis
skin disease
immunological deviation
atopic eczema
skin structure
skin infection
skin barrier
Opis:
Atopic eczema (AE) is a multifactorial skin disease caused by a variety of factors such as genetic conditions, alterated skin structure, immunologic deviations and environmental factors, among others. There are two main subtypes of AE, i.e. the IgE-associated (“atopic eczema”) and the non-IgE-associated type (“nonatopic eczema”) with different prognosis concerning the development of respiratory diseases (“atopy march”). Recently, it was demonstrated that Filaggrin (= fi lament-aggregating protein, FL) is a major gene for atopic eczema. Filaggrin binds to and aggregates the keratin cytoskeleton in the epidermis. Homozygous FLG mutation leads to complete loss of fi laggrin expression in skin. Half or more of children with moderate to severe AE carry FLG mutations. Moreover, fi laggrin loss-of-function mutations predispose to phenotypes involved in the atopy march. The altered skin structure and a defi ciency in antimicrobial peptides favour colonization with Staphylococcus aureus and yeasts (Malassezia sp.). Sensitization to the yeast occurs almost exclusively in AE patients. S. aureus enterotoxins with superantigenic activity stimulate activation of T cells and macrophages. So far, AE skin lesions are orchestrated by the local tissue expression of proinfl ammatory cytokines and chemokines with activation of T lymphocytes, dendritic cells, macrophages, keratinocytes, mast cells, and eosinophils which lead to the skin infl ammatory responses. From the therapeutic point of view, besides emollients and local corticosteroids, topic immunomodulatory drugs (tacrolimus and pimecrolimus) have substantially improved the treatment of AE.
Źródło:
Annals of Agricultural and Environmental Medicine; 2007, 14, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł

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