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Wyszukujesz frazę "neuroendocrine tumour" wg kryterium: Temat


Wyświetlanie 1-2 z 2
Tytuł:
The role of endoscopic ultrasound in diagnosing pancreatic neuroendocrine tumours
Autorzy:
Dyrla, Przemysław
Chmielewska, Magdalena
Mazur, Marta
Witek, Przemysław
Powiązania:
https://bibliotekanauki.pl/articles/1035844.pdf
Data publikacji:
2018
Wydawca:
Medical Education
Tematy:
endoscopic ultrasound
pancreatic neuroendocrine tumour
ultrasonography
Opis:
Pancreatic tumour imaging poses one of the greatest challenges in gastroenteropancreatic tumour diagnostics. Though much less common than adenocarcinomas, tumours deriving from pancreatic islets are the second most common group of pancreatic tumours. The manifestations and growth rate of neuroendocrine tumours (NETs) differ from adenocarcinomas; thus, these tumour types require different diagnostic and therapeutic approaches. With its high sensitivity and specificity, endoscopic ultrasound (EUS) seems to be indispensable in pancreatic NET diagnostics. A negative EUS practically excludes the presence of a pancreatic tumour, while in definitive tumour cases, EUS is helpful in tumour staging, and in determining its precise anatomical location. One especially important benefit of EUS is the option of performing a biopsy for subsequent cytological and histopathological examinations. The use of contrast and additional computerized image analysis increases the diagnostic accuracy of EUS. This article presents current views on the use of EUS in pancreatic tumour diagnostics, with a particular emphasis on diagnosing NETs.
Źródło:
OncoReview; 2018, 8, 1; 19-23
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Long-standing acromegaly in a patient with a pituitary adenoma not visible on MRI
Autorzy:
Kurowska, Maria
Malicka, Joanna
Tarach, Jerzy S.
Powiązania:
https://bibliotekanauki.pl/articles/1061851.pdf
Data publikacji:
2017
Wydawca:
Medical Education
Tematy:
acromegaly
ectopic GHRH secretion
microadenoma
neuroendocrine tumour
Opis:
Introduction: Acromegaly in the course of a pituitary microadenoma or neuroendocrine GHRH-secreting tumour (GHRH, growth hormone-releasing hormone) invisible on MRI is very rare. Objective: To present the difficulties in determining the cause behind an excessive production of the growth hormone in a patient suffering from long-standing acromegaly, without a pituitary focal lesion that would be visible on MRI. Case report: The authors describe a case of a 69-year-old female with acromegaly, diagnosed 22 years earlier based on the typical somatic symptoms, and confirmed by the elevated concentration of insulin- like growth factor type 1 and lack of growth hormone suppression in the oral glucose tolerance test. The initial MRI scan (1994) had revealed a hypoechogenic 2 x 3 mm lesion in the anterior lobe of the pituitary gland, whose presence was not reported in the subsequent MRI tests. As ectopic GHRH or growth hormone secretion was suspected, a neuroendocrine tumour was searched for. The 47.7 × 54 × 35.7 mm tumour, located in the thoracic outlet, accumulating tektreotide in receptor scintigraphy, turned out to be a nodular goitre on histopathology. Due to the undetermined location of the source of growth hormone overproduction, failure to measure GHRH levels, and the patient’s lack of consent to undergo sella turcica exploration, long-acting release octreotide had been used for many years to manage the patient’s condition. Conclusion: The long-lasting and ineffective search for a neuroendocrine tumour producing GHRH or growth hormone as well as the absence of a focal lesion in the repeated MRI scans render it impossible to unequivocally determine the cause of the patient’s acromegaly, and illustrate the difficulties in discovering the source of growth hormone overproduction.
Źródło:
OncoReview; 2017, 7, 1; 32-37
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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