- Tytuł:
- Mechanosensitivity of cell membrane may govern creep-strain recovery, osmotic expansion and lysis
- Autorzy:
- Pawłowski, Piotr
- Powiązania:
- https://bibliotekanauki.pl/articles/1040543.pdf
- Data publikacji:
- 2009
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
mechanosensitivity
caveolae
exocytosis
surface tension
endocytosis
cell membrane - Opis:
- A simple theoretical model considering cell membrane mechanosensitivity can accurately describe published experimental data on membrane area creeping and recovery, and on osmotic expansion and rupture. The model to data fit reveals real values of membrane tension and elasticity modulus, and the parameters describing membrane organization and kinetics of mechanosensitive membrane traffic, including small solute transport, water permeability, endocytosis, exocytosis, and caveolae formation. This estimation allows for separation and quantitative analysis of the participation of different processes constituting the response of plasmalemma to short time-scale membrane load. The predicted properties of the model were verified for membrane stretching at different osmotic pressures. Finally, a simple hypothesis concerning stressed cell membrane breakdown is postulated.
- Źródło:
-
Acta Biochimica Polonica; 2009, 56, 3; 471-480
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł