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    Wyświetlanie 1-13 z 13
    Tytuł:
    Polyester-camptothecin conjugates for controlled release
    Autorzy:
    Sobczak, M.
    Olędzka, E.
    Kuras, M.
    Luchowska, U.
    Świniarska, L.
    Wyrębiak, R.
    Nałęcz-Jawecki, G.
    Powiązania:
    https://bibliotekanauki.pl/articles/284000.pdf
    Data publikacji:
    2016
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    polyesters
    camptothecin
    alkaloids
    Źródło:
    Engineering of Biomaterials; 2016, 19, 138; 45
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Magnoflorine - a compound with anti-tumour activity
    Autorzy:
    Baran, M.
    Miziak, P.
    Bonio, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/2097708.pdf
    Data publikacji:
    2020
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    biosynthesis
    alkaloids
    antitumour activity
    magnoflorin
    Opis:
    Introduction. Alkaloids are a large group of organic compounds of natural origin. One of the most popular alkaloids is magnoflorine. This compound is synthesized by plants from the Ranunculaceae, Menispermaceae and Magnoliaceae families. Magnoflorine has unique biological properties and a broad spectrum of physiotherapeutic activity. It has antibacterial, antifungal, antidiabetic, immunomodulating and anticancer properties. Objective.The aim of the study is to present magnoflorine as a compound with anti-cancer potential. Brief description of the state of knowledge. Magnoflorine is a compound belonging to the isoquinolone alkaloids. Metabolized by secondary metabolism it is most commonly collected in the roots, rhizomes, tubers and bark of plants. It can be isolated from all plant elements by chromatographic methods. Magnoflorine has a number of therapeutic properties, including anti-cancer. Magnoflorine has been shown to inhibit cell proliferation, migration and cause apoptosis. The possibility of using this compound in the treatment of breast and stomach cancer has been confirmed. Results. The combination of DOX with magnoflorine reduces the expression of Bcl-2 and enhances the cleavage of caspase-9 and -3, causing apoptosis in breast cancer cells. Moreover, they block the activation of PI3K / AKT / mTOR signaling, which play an important role in regulating tumour growth. Magnoflorine inhibits the activity of caspases in liver cancer cells, resulting in inhibition of proliferation. Conclusion. Magnoflorine is an interesting research target due to its unique anticancer properties. Detailed knowledge of the pharmacological possibilities of magnoflorine will enable its effective use in the prevention and treatment of many civilization diseases.
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2020, 14, 3; 98-101
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The Suzuki-Miyaura reaction in the chemical transformations of vindoline
    Autorzy:
    Ruszkowska, Joanna
    Chrobak, Robert
    Żero, Paweł
    Maurin, Jan
    Szawkało, Joanna
    Czarnocki, Zbigniew
    Powiązania:
    https://bibliotekanauki.pl/articles/1040884.pdf
    Data publikacji:
    2007
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    alkaloids
    chemotherapy
    bioorganic chemistry
    natural products
    Opis:
    Vindoline and its analogues are important constituents of the Madagascan periwinkle Catharanthus roseus, and some of them are valuable chemotherapy drugs used in treatment for some types of cancer, including leukaemia, lymphoma, breast and lung cancer. The search for semi-synthetic congeners of natural substances is still an important task for organic chemistry. In this communication we report the synthesis of five new vindoline derivatives, 15-(2-methoxyphenyl)vindoline 11, 15-(3-methoxyphenyl)vindoline 12, 15-(2-nitrophenyl)vindoline 13, 15-(3-cyanophenyl)vindoline 15, and 15-(4-cyanophenyl)vindoline 16 using the Suzuki-Miyaura reaction as the key step. X-Ray analysis of compound 16 is also reported.
    Źródło:
    Acta Biochimica Polonica; 2007, 54, 4; 857-861
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    New method for the study of Amaryllidaceae alkaloid biosynthesis using biotransformation of deuterium-labeled precursor in tissue cultures
    Autorzy:
    El Tahchy, Anna
    Boisbrun, Michel
    Ptak, Agata
    Dupire, François
    Chrétien, Françoise
    Henry, Max
    Chapleur, Yves
    Laurain-Mattar, Dominique
    Powiązania:
    https://bibliotekanauki.pl/articles/1040425.pdf
    Data publikacji:
    2010
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    alkaloids
    Leucojum aestivum
    Amaryllidaceae
    deuterated precursor
    biotransformation
    Opis:
    Biotransformation of deuterated-4'-O-methylnorbelladine into alkaloids galanthamine and lycorine in tissue cultures of Leucojum aestivum was demonstrated using HPLC coupled to mass spectrometry. GC-MS screening was also carried to investigate other native and deuterated alkaloids. A total of six labeled alkaloids were identified indicating that 4'-O-methyl-d3-norbelladine is incorporated into three different groups of Amaryllidaceae alkaloids that are biosynthesized by three modes of intramolecular oxidative phenol coupling.
    Źródło:
    Acta Biochimica Polonica; 2010, 57, 1; 75-82
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Plant secondary metabolites as defenses: A review
    Autorzy:
    Jusuf, Herlina
    Elveny, Marischa
    Azizova, Feruza
    Shichiyakh, Rustem A.
    Kulikov, Dmitriy
    Al-Taee, Muataz M.
    Atiyah, Karrar K.
    Jalil, Abduladheem T.
    Aravindhan, Surendar
    Powiązania:
    https://bibliotekanauki.pl/articles/2174280.pdf
    Data publikacji:
    2022
    Wydawca:
    Instytut Technologiczno-Przyrodniczy
    Tematy:
    alkaloids
    flavonoids
    phenolics
    plant pathogens
    secondary metabolites
    Opis:
    Plant secondary metabolites have a variety of functions, including mediating relationships between organisms, responding to environmental challenges, and protecting plants against infections, pests, and herbivores. In a similar way, through controlling plant metabolism, plant microbiomes take part in many of the aforementioned processes indirectly or directly. Researchers have discovered that plants may affect their microbiome by secreting a variety of metabolites, and that the microbiome could likewise affect the metabolome of the host plant. Pesticides are agrochemicals that are employed to safeguard humans and plants from numerous illnesses in urban green zones, public health initiatives, and agricultural fields. The careless use of chemical pesticides is destroying our ecology. As a result, it is necessary to investigate environmentally benign alternatives to pathogen management, such as plant-based metabolites. According to literature, plant metabolites have been shown to have the ability to battle plant pathogens. Phenolics, flavonoids, and alkaloids are a few of the secondary metabolites of plants that have been covered in this study.
    Źródło:
    Journal of Water and Land Development; 2022, 55; 206--211
    1429-7426
    2083-4535
    Pojawia się w:
    Journal of Water and Land Development
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Qualitative and quantitative evaluation of secondary metabolites of different plant extracts of Nothapodytes foetida (Wight) Sleumer an important endangered medicinal tree
    Autorzy:
    Bai, D. Sunitha
    Suvarchala, V.
    Pavani, Ch.
    Chaithanya, G.
    Spoorthi, V.
    Shasthree, T.
    Powiązania:
    https://bibliotekanauki.pl/articles/1839343.pdf
    Data publikacji:
    2021
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Camptothecin
    phytochemicals
    alkaloids
    flavonoids
    glycosides
    tannins
    phenols
    triterpenoids
    saponins
    Nothapodytes foetida
    Opis:
    The present study of phytochemical screening has revealed valuable information about the chemical constituents of Nothapodytes foetida. Phytochemical analysis of leaves, stem, bark and root extracts of Nothapodytes foetida was performed using different solvent systems such as chloroform, butanol, hexane, methanol and acetonitrile for the presence of different phytochemicals with standard procedures. The phytochemical screening (both qualitative and quantitative) of variousplant extracts of Nothapodytes foetida revealed the presence of different phytoconstituents such as alkaloids, flavonoids, glycosides, tannins, phenols and triterpenoids. Among all the solvents tested, methanol, butanol and chloroform extract of leaf, stem, bark and root showed high concentration of all phytoconstituents compared to hexane and acetonitrile solvent extracts. The total quantity of secondary metabolites was evaluated by using the standard procedures and the line of regression and the regression coefficient estimated from the calibration curve of various standards. The highest quantity of phytoconstituent present in the plant extracts was identified to be alkaloids. The alkaloid content of leaf was evaluated to be 66.11±0.47, whereas stem possess 56.27±0.38, bark 59.02±0.17 and root 62.34±0.27 mg AE/gm of extracts and subsequent high amounts of phytoconstituents identified was flavonoids, tannins, phenols and saponins. Phytochemical screening of Nothapodytes foetidaused in the medical field for the design of new drugs.
    Źródło:
    World Scientific News; 2021, 162; 43-59
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Separation of matrine and oxymatrine from Sophora flavescens extract through cation exchange resin coupled with macroporous absorption resin
    Autorzy:
    Chen, H.
    Luo, S.
    Zheng, X.
    Fan, H.
    Powiązania:
    https://bibliotekanauki.pl/articles/778382.pdf
    Data publikacji:
    2016
    Wydawca:
    Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
    Tematy:
    Sophora flavescens
    BS-65 macroporous resin
    001×732 cation exchange resin
    separation
    alkaloids
    Opis:
    A simple method for separation of matrine and oxymatrine from Sophora flavescens was developed with cation exchange resin coupled with macroporous resin. Based on the adsorption characteristics of matrine and oxymatrine, 001×732 cation exchange resin was used to absorb target alkaloids for removing most of the foreign matter, while BS-65 macroporous resin was chosen to purify these alkaloids. The result showed that the equilibrium adsorption data of matrine and oxymatrine on 001×732 resin and BS-65 resin at 30°C was fitted to Langmuir isotherm and Freundlich isotherm, respectively. The contents of matrine and oxymatrine were increased from 0.73% and 2.2% in the crude extract of the root of Sophora flavescens to 67.2% and 66.8% in the final eluent products with the recoveries of 90.3% and 86.9%, respectively.
    Źródło:
    Polish Journal of Chemical Technology; 2016, 18, 2; 31-39
    1509-8117
    1899-4741
    Pojawia się w:
    Polish Journal of Chemical Technology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Synteza estru dietylowego kwasu 3,4-bis(4-metoksyfenylo)-1H-pirolo-2,5-dikarboksylowego, półproduktu w syntezie alkaloidów z grupy Polycitone, Lamellarin i Storniamide
    Synthesis of diethyl 3,4-bis(4-methoxyphenyl)-1H-pyrrole-2,5-dicarboxylate, semi-synthetic alkaloids from Polycitone, Lamellarin and Storniamide
    Autorzy:
    Buszta, Natalia
    Powiązania:
    https://bibliotekanauki.pl/articles/31342672.pdf
    Data publikacji:
    2017
    Wydawca:
    Politechnika Rzeszowska im. Ignacego Łukasiewicza. Oficyna Wydawnicza
    Tematy:
    kondensacja Knoevenagela
    redukcja
    dimeryzacja utleniająca
    alkaloidy morskie
    Knoevenagel condensation
    reduction
    oxidative dimerization
    marine alkaloids
    Opis:
    Opisano syntezę symetrycznie podstawionej pochodnej pirolu, użytecznego produktu pośredniego w syntezie znanych alkaloidów i ich analogów pochodzenia morskiego. Substratem jest aldehyd anyżowy, który w sześciu etapach, z wykorzystaniem m. in.: kondensacji Knoevenagela, uwodornienia alifatycznego wiązania podwójnego i kluczowej pośredniej utleniającej dimeryzacji 2-azydo-3-(4-metoksyfenylo)propionianu etylu chlorkiem tytanu (IV), pozwala na otrzymanie tytułowej pochodnej.
    Synthesis of a new building block of symmetrically substituted pyrrole derivative, which is useful intermediate in the synthesis of known alkaloids and their marine analogues, is described. The substrate is anisaldehyde, which in six steps with the use of Knoevenagel condensation, hydrogenation of the aliphatic double bond and the key titanium (IV)-mediated oxidative dimerization of 2-azidocarboxylic ester allows to obtain the title derivative.
    Źródło:
    Chemical Technology & Biotechnology; 2017, 1; 17-22
    2720-6793
    Pojawia się w:
    Chemical Technology & Biotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Ostatnie postępy w syntezie alkaloidów tropanowych i pochodnych tropanu
    Recent advances in the synthesis of tropane alkaloids and other tropane derivatives
    Autorzy:
    Sidorowicz, K.
    Kropiwnicki, K.
    Łaźny, R.
    Powiązania:
    https://bibliotekanauki.pl/articles/171941.pdf
    Data publikacji:
    2015
    Wydawca:
    Polskie Towarzystwo Chemiczne
    Tematy:
    synteza
    alkaloidy tropanowe
    pochodne tropanów
    synteza stereoselektywna
    synthesis
    tropane alkaloids
    tropane derivatives
    stereoselective synthesis
    Opis:
    Tropane alkaloids are a long-known class of compounds possessing an 8-azabicyclo[ 3.2.1]octane skeleton. Many tropane alkaloids posses biological activity (anticholinergic, anti-Parkinsonian, hypotensive), and as such had a significant influence on medicine and played a notable role in the development of organic chemistry [1]. The most known representatives of biologically active tropane alkaloids are: cocaine, atropine, scopolamine, ecgonine, and Bao Gong Teng A. A number of natural tropane alkaloids are chiral compounds, whose preparation in optically active forms is still a big challeng [2]. The biological activity of enantiomers often differs depending on their configurations. Alkaloids are a subject of an intensive research: scopus database contains nearly 200 thousand publications with the word „alkaloid”, and almost 4,500 publications with the phrase „tropane alkaloids” (about half of them have appeared in the last ten years). About 55 papers are devoted to stereoselective synthesis of tropane derivatives in 2000-2015. About half of this concernes stereoselective methods. The organic synthesis of alkaloids has a long history and numerous synthetic approaches to the tropane skeleton have been developed, from the classical synthesis of tropinone by Willstätter at the beginning of the XX century, to more recent developments dealing with asymmetric deprotonation of tropinone with chiral lithium amide bases for the enantioselective synthesis of a range of tropanes [3, 4]. Owing to extensiveness of the field, the current review presents the most interesting, from a synthetic point of view, approaches to tropane derivatives and tropane analogues. Most of the methods of synthesis are long (often several steps), time- and recourses-intensive, and often required elaborate and hardly available starting materials. But there are also notable exceptions, based on the asymmetric deprotonation approach; e.g., from the syntheses of cocaine described in this article, the most efficient one was reported by Lee in 2000 [5]. The concise synthesis (6 steps) gave the unnatural enantiomer of cocaine starting from commercially available tropinone in 78% overall yield. This approach allows to obtain both enantiomers and racemate, by changing type of one reactant only. However, most strategies provide only one enantiomer or racemic mixture of an alkaloid. As can be seen, despite of advances in chemicall science, there is no general way to synthesize majority of the representatives of this group of structurally related compounds.
    Źródło:
    Wiadomości Chemiczne; 2015, 69, 11-12; 1019-1045
    0043-5104
    2300-0295
    Pojawia się w:
    Wiadomości Chemiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Badania strukturalne cyklicznych β-aminoketonów z wykorzystaniem metod obliczeniowych i analizy NMR
    Structural studies of cyclic β-amino ketons using computational and NMR methods
    Autorzy:
    Sidorowicz, K.
    Łaźny, R.
    Powiązania:
    https://bibliotekanauki.pl/articles/142626.pdf
    Data publikacji:
    2015
    Wydawca:
    Stowarzyszenie Inżynierów i Techników Przemysłu Chemicznego. Zakład Wydawniczy CHEMPRESS-SITPChem
    Tematy:
    alkaloidy
    konformacje
    teoria funkcjonału gęstości
    spektroskopia NMR
    alkaloids
    conformations
    density functional theory
    NMR spectroscopy
    Opis:
    Przestrzenna konfiguracja na atomie azotu w cyklicznych β-aminoketonach powoduje, że związki te mogą występować w dwóch stereoizomerycznych formach, w których podstawniki na tym atomie mogą przyjmować orientację aksjalną lub ekwatorialną w stosunku do pierścienia piperydonu. Stereochemia N-podstawionych bicyklicznych β-aminoketonów była badana za pomocą metod eksperymentalnych i teoretycznych, m.in.: spektroskopia NMR, spektroskopii mikrofalowa, rentgenografii strukturalnej i obliczeń DFT.
    Because of pyramidal configuration of the nitrogen atom, tropanes, granatanes, and their derivatives can exist in two stereoisomeric forms, in which N-substituents can be oriented axial or equatorial with respect to the piperidone ring. The N-invertomer stereochemistry of N-substituted bicyclic β-amino ketones has been investigated using experimental, and theoretical methods, such as NMR, microwave spectroscopy, crystallography, and DFT calculations.
    Źródło:
    Chemik; 2015, 69, 7; 401-410
    0009-2886
    Pojawia się w:
    Chemik
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Antioxidant and antimicrobial activity of essential oils extracted from aromatic plants
    Autorzy:
    Yahaya, Muhammad F.
    Kubmarawa, Dimas
    Yelwa, Jibrin M.
    Runde, Musa
    Powiązania:
    https://bibliotekanauki.pl/articles/1162022.pdf
    Data publikacji:
    2018
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Antimicrobial
    Antioxidant
    Cananga odorata
    Citrus limon
    Essential oils
    Phytochemical screening
    Vitex trifolia
    bioactive agents and Alkaloids
    Opis:
    The antimicrobial and antioxidant activities of extracted essential oils in some aromatic plants were determined. Phytochemical screening was conducted using standard qualitative techniques, while the essential oils was extracted from the Citrus limon linn leaf, Vitex trifolia seed and Cananga odorata by modified steam distillation apparatus. Furthermor, the plant materials were tested using Antioxidant activity and Antimicrobial activity test. Citrus limon linn produced large volume essential oil (1.4 ml), Vitex trifola (0.7 ml) and Cananga odorata (0.5 ml) after 3hours of steam distillation. Antioxidant activities test using DPPH method reveals that all the essential oil determined showed positive effect, but the oil extracted from Citrus limon linn leaf could be a better antioxidant than that of Vitex tifolia and Cananga odorat when compared to commercial Ascorbic acid. The antioxidant activities of the essential oils of different plants under investigation showed a variation which may be as a result of the difference in their chemical compositions. Antimicrobial activities showed that all the essential oils were inhibited on the entire five microorganisms being used. However, Citrus limonlinn showed highest inhibition on the organisms (E. coli, S. typhi C. Kleb, P. avengunosa and S. aureus) compared to Cananga odorata and Vitex trifolia.
    Źródło:
    World Scientific News; 2018, 111; 13-25
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Alkaloidy kory chinowej : małe cząsteczki, które wiele mogą
    Cinchona alkaloids : small hardworkers
    Autorzy:
    Kacprzak, K.
    Czarnecki, P.
    Powiązania:
    https://bibliotekanauki.pl/articles/172207.pdf
    Data publikacji:
    2013
    Wydawca:
    Polskie Towarzystwo Chemiczne
    Tematy:
    chinina
    alkaloidy kory chinowej
    chinidyna
    synteza asymetryczna
    rozdział enancjomerów
    chiralność
    quinine
    cinchona alkaloids
    quinidine
    asymmetric synthesis
    enantiomer separation
    chirality
    Opis:
    Cinchona alkaloids comprising quinine, quinidine, cinchonidine and cinchonine as the major members constitute a unique class of quinoline alkaloids with tremendous impact on human civilization (Section 1). The odyssey of Cinchona alkaloids began with the discovery of their antimalarial properties followed by antiarrhytmic action of quinidine. Currently medicinal chemistry of Cinchona alkaloids derivatives develops rapidly and many other activities such as cytotoxic, multidrug resistance inhibitory have been demonstrated (Section 5) [5]. Beside medicine Cinchona alkaloids gave also the fundaments of stereochemistry and asymmetric synthesis. An extraordinary catalytic potency of parent and modified Cinchona alkaloids (deserving privileged catalyst classification) include more than 50 types of diverse stereoselective reactions, with few spectacular such as asymmetric dihydroxylation of alkenes or heterogeneous α-ketoesters hydrogenation (Section 3) [3]. Last but not least the portfolio of applications of Cinchona alkaloids includes resolution of racemates by diastereomeric crystallization or by the use of Cinchona- -based chiral stationary phases for ion-exchange enantioselective chromatography and other recognition or sensing systems (Section 4) [166]. Easy transformation of Cinchona alkaloids (for example by click chemistry) into other chiral and modular building blocks together with current pressure on a more intense exploration of sustainable products make cinchona alkaloids of primary importance for modern synthetic, catalytic and medicinal chemistry. The aim of this review which covers over 200 references is to briefly summarize all aspects of Cinchona alkaloid chemistry and biology with the special emphasis on new applications.
    Źródło:
    Wiadomości Chemiczne; 2013, 67, 5-6; 443-493
    0043-5104
    2300-0295
    Pojawia się w:
    Wiadomości Chemiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Metabolity wtórne – znaczenie w środowisku przyrodniczym i gospodarce człowieka
    Secondary metabolites – importance in the natural environment and human economy
    Autorzy:
    Nowak, Dorota
    Piekutin, Janina
    Powiązania:
    https://bibliotekanauki.pl/chapters/27317147.pdf
    Data publikacji:
    2023-07-19
    Wydawca:
    Politechnika Częstochowska. Wydawnictwo Politechniki Częstochowskiej
    Tematy:
    metabolity wtórne
    rośliny
    grzyby
    flawonoidy
    alkaloidy
    terpeny
    mykotoksyny
    biocydy
    Trichoderma
    secondary metabolites
    plants
    fungi
    flavonoids
    alkaloids
    terpenes
    mycotoxins
    biocides
    Opis:
    Metabolity wtórne to bardzo różnorodna grupa związków chemicznych naturalnie produkowanych przez organizmy. Spełniają one funkcje sygnałów biochemicznych, które umożliwiają komunikację między organizmami. Te niskocząsteczkowe związki organiczne działają jako chemomediatory ekologiczne, pełniąc funkcje obronne, przywabiające, ułatwiające rozmnażania, a także regulacyjne. Metabolity wtórne produkowane są przez bakterie właściwe, promieniowce, grzyby, glony, a także zwierzęta. Poznanie budowy oraz właściwości biologicznych umożliwiło zastosowanie metabolitów wtórnych w produkcji ważnych leków, takich jak: antybiotyki, leki przeciwnowotworowe, przeciwbólowe, immunosupresyjne, obniżające poziom cholesterolu lub regulujące poziom cukru we krwi. Metabolity wtórne mogą być zastosowane także jako naturalne i mniej szkodliwe środki ochrony roślin zwalczające fitopatogeny. Wśród metabolitów wtórnych są również silnie działające związki toksyczne, jak np. mykotoksyny produkowane przez grzyby. W rozdziale dokonano przeglądu literatury na temat budowy, funkcji ekologicznych oraz znaczenia wybranych metabolitów wtórnych roślin oraz grzybów.
    Secondary metabolites are a very diverse group of chemical compounds naturally produced by organisms. They perform functions of biochemical signals and enable communication between organisms. They are low-molecular organic compounds and act as ecological chemomediators. They perform defensive, attracting, facilitating reproduction, and regulatory functions. Secondary metabolites are produced by bacteria, actinomycetes, fungi, algae, as well as animals. Knowledge of the structure and biological properties has made it possible to use secondary metabolites in the production of important drugs such as antibiotics, anticancer drugs, painkillers, immunosuppressants, cholesterol-lowering or blood sugar-regulating drugs. Secondary metabolites can also be used as natural and less harmful plant protection products to combat phytopathogens. Among secondary metabolites are also potent toxic compounds such as: mycotoxins produced by fungi. This chapter reviews the literature on the structure, ecological functions and importance of selected secondary metabolites of plants and fungi.
    Źródło:
    Inżynieria środowiska i biotechnologia. Wyzwania i nowe technologie; 201-214
    9788371939013
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
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