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Wyświetlanie 1-15 z 210
Tytuł:
Sensitivity analysis of deterministic signaling pathways models
Autorzy:
Puszyński, K.
Lachor, P.
Kardyńska, M.
Śmieja, J.
Powiązania:
https://bibliotekanauki.pl/articles/201589.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
signaling pathways
sensitivity analysis
Opis:
The paper is focused on application of sensitivity methods to analysis of signaling pathway models. Two basic methods are compared: local, based on standard sensitivity functions, and global, based on Sobol indices. Firstly, a general outline of modeling of signaling pathways by means of ordinary differential equations is briefly described. Afterwards, the methods of sensitivity analysis, known from literature, are introduced and illustrated with a simple example of a dynamical system of the second order. Subsequently, the analysis of the p53/Mdm2 regulatory module, which is a key element of any pathway involving p53 protein, is presented. The results of this analysis suggest that no single method should be chosen for investigation of any signaling pathway model but several of them should be applied to answer important questions about sources of heterogeneity in cells behavior, robustness of signaling pathways and possible molecular drug targets.
Źródło:
Bulletin of the Polish Academy of Sciences. Technical Sciences; 2012, 60, 3; 471-479
0239-7528
Pojawia się w:
Bulletin of the Polish Academy of Sciences. Technical Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Economic analysis of implementing VMI model using game theory
Autorzy:
Stehel, Vojtěch
Vochozka, Marek
Kliestik, Tomas
Bakes, Vladimir
Powiązania:
https://bibliotekanauki.pl/articles/19090921.pdf
Data publikacji:
2019
Wydawca:
Instytut Badań Gospodarczych
Tematy:
VMI
game theory
sensitivity analysis
Opis:
Research background: The article deals with implementing VMI between the supplier and customer. To assess whether the system will be implemented, the evolution game theory is used. The contribution is based on the limitations of the study of the evolutionary game theory approach to modelling VMI policies (Torres et al., 2014) and its later extension, The evolutionary game theory approach to modelling VMI policies (Torres & García-Díaz, 2018). It aims is to complement the studies and provide a comprehensive picture of the issue. Purpose of the article: The main objective of the contribution is to respond to the question whether the VMI system will be introduced between the supplier and customer. Methods: In the first phase, the matrix is analysed from the point of view of the game meaning and its limit parameters. The limit parameters are set taking into account the economic reality. The only examined states of the matrix are those where the result is not obvious. For the purposes of the contribution, we work with a 5-year period. A new software capable of calculating evolutionary focus and their stability is created. Sensitivity analysis is carried out for the individual parameters that affect the system behaviour. Findings & Value added: Value added is a complex description of the system and complementation of previous studies in this field. VMI is confirmed. The results obtained can be used for practical management, so that the managers are able to identify what the actual costs are and what the probability of introducing the system is. At the same time, they can identify the parameters that can be influenced by them and observe their impact on the shift of the system introduction probability.
Źródło:
Oeconomia Copernicana; 2019, 10, 2; 253-272
2083-1277
Pojawia się w:
Oeconomia Copernicana
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
High order sensitivity analysis of a mistuned blisk including intentional mistuning
Autorzy:
Pohle, L.
Tatzko, S.
Panning-von Scheidt, L.
Wallaschek, J.
Powiązania:
https://bibliotekanauki.pl/articles/281842.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Mechaniki Teoretycznej i Stosowanej
Tematy:
turbine blades
mistuning
sensitivity analysis
Opis:
Small deviations between turbine blades exist due to manufacturing tolerances or material inhomogeneities. This effect is called mistuning and usually causes increased vibration amplitudes and also a lower service life expectancy of bladed disks or so called blisks (bladed integrated disk). The major resulting problem is to estimate the maximum amplitude with respect to these deviations. Due to the probability distribution of these deviations, statistical methods are used to predict the maximum amplitude. State of the art is the Monte-Carlo simulation which is based on a high number of randomly re-arranged input parameters. The aim of this paper is to introduce a useful method to calculate the probability distribution of the maximum amplitude of a mistuned blisk with respect to the random input parameters. First, the applied reduction method is presented to initiate the sensitivity analysis. This reduction method enables the calculation of the frequency response function (FRF) of a Finite Element Model (FEM) in a reasonable calculation time. Based on the Taylor series approximation, the sensitivity of the vibration amplitude depending on normally distributed input parameters is calculated and therewith, it is possible to estimate the maximum amplitude. Calculating only a single frequency response function shows a good agreement with the results of over 1000 Monte-Carlo simulations.
Źródło:
Journal of Theoretical and Applied Mechanics; 2017, 55, 1; 353-368
1429-2955
Pojawia się w:
Journal of Theoretical and Applied Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sensivity and design of fiber layout in composites
Autorzy:
Dems, K.
Powiązania:
https://bibliotekanauki.pl/articles/279497.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Mechaniki Teoretycznej i Stosowanej
Tematy:
sensitivity analysis
composites
fiber layout
optimization
Opis:
For a linear structure reiforced with elastic fibers, the first variation of an arbitrary behavioral functional corresponding to variation of shape or orientation of fibers is derived by using the direct approach to sensivity analysis. The relevant optimality conditions for optimal design and identification problems are then derived. Both the static and dynamic loading cases are considered. Some simple examples illustrate the applicability of the presented approach.
Wrażliwość i projektowanie ułożenia włókien w kompozycie. W pracy rozpatrzono pierwszą wariację dowolnego funkcjonału związaną z wariacją kształtu lub orientacji wzmacniających włókien w płaskiej liniowo-sprężystej tarczy. Wrażliwości rozpatrywanego funkcjonału wyznaczono wykorzystując metodę bezpośrednią analizy wrażliwości. Następnie sformułowano typowy problem optymalnego projektowania oraz problem identyfikacyjny i wyznaczono odpowiednie warunki optymalności. Rozpatrzono zarówno przypadek obciążeń statycznych, jak i dynamicznych.
Źródło:
Journal of Theoretical and Applied Mechanics; 2000, 38, 4; 807-818
1429-2955
Pojawia się w:
Journal of Theoretical and Applied Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A remark on sensitivity in linear programming and Gale-Samuelson nonsubstitution theorem
Autorzy:
De Giuli, M. E.
Giorgi, G.
Powiązania:
https://bibliotekanauki.pl/articles/969906.pdf
Data publikacji:
2010
Wydawca:
Polska Akademia Nauk. Instytut Badań Systemowych PAN
Tematy:
linear programming
sensitivity analysis
nonsubstitution theorem
Opis:
The main purpose of this paper is to show that David Gale's result (1960, Lemma 9.3 on sensitivity in linear programming) is not generally valid. In this lemma, additional assumptions, that are instead required, are not made. We give some correct versions of the above mentioned lemma, and with these an elementary proof of the Gale-Samuelson nonsubstitution theorem.
Źródło:
Control and Cybernetics; 2010, 39, 3; 827-838
0324-8569
Pojawia się w:
Control and Cybernetics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sensitivity Analysis and Optimization for Selected Supply Chain Management Issues in the Company – Using System Dynamics and Vensim
Autorzy:
Kasperska, Elżbieta
Mateja-Losa, Elwira
Marjasz, Rafał
Powiązania:
https://bibliotekanauki.pl/articles/475034.pdf
Data publikacji:
2013
Wydawca:
Fundacja Upowszechniająca Wiedzę i Naukę Cognitione
Tematy:
System Dynamics
sensitivity analysis
optimization
Vensim
Opis:
The aim of our paper is to present the new results of research work on optimization and simulation for some logistic problems in the company. The System Dynamics (SD) method and the Vensim simulation language are applied in order to solve specific managerial problems described by Forrester in the model of supply chain. The historical model of Customer-Producer-Employment System by Forrester (Forrester, 1961) has not been examined with the sensitivity analysis, from the “automatic” testing perspective. Optimization experiments have not been conducted, either. It is surprising, since the model is old and widely known. The opportunities offered by the Vensim language allow us to perform such analysis. The visualization called “confidence bounds“ is used, to show the behaviour of chosen variables over a period of time. The Monte-Carlo method is applied for sampling a set of numbers from within bounded domains (distribution for each searching parameters is specified). The authors of this paper conducted numerous experiments in this scope. This paper presents their results and offers some conclusions formulated at the end.
Źródło:
Journal of Entrepreneurship, Management and Innovation; 2013, 9, 2; 29-44
2299-7075
2299-7326
Pojawia się w:
Journal of Entrepreneurship, Management and Innovation
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Exploring the role of socio-economic and built environment driving factors in shaping the commuting modal share: a path-analysis-based approach
Autorzy:
Boukarta, Soufiane
Berezowska-Azzag, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1050982.pdf
Data publikacji:
2020-12-21
Wydawca:
Uniwersytet im. Adama Mickiewicza w Poznaniu
Tematy:
commuting
questionnaire
sensitivity analysis
path analysis
Djelfa (Algeria)
Opis:
This paper explores the role of the built environment and socio-economic drivers in shaping the modal share of commuting. For this, we have identified through our literature review 67 potential variables categorised into two groups; the built environment and the households’ socio-economic characteristics. We have considered the city of Djelfa as a case study and used the questionnaire as a data collection tool. The questionnaire processing of the 700 questionnaires provided to the households allowed us to select 184 questionnaires for our analysis. The sensitivity analysis protocol is designed for two stages; (i) an exploratory stage, conducted by principal component analysis and bivariate correlation analysis; (ii) and a confirmatory stage conducted by a path analysis. The first step allowed us to hypothesise several causal pathways that could explain, directly or indirectly, the modal share of commuting. The results of the path analysis show that the modal shares of walking, private car and public transit are controlled by 13, 16 and 12 explanatory variables, respectively. Overall, the socio-economic characteristics of households discourage walking and transit use, and encourage private car commuting. On the other hand, the variables identified in this paper related to the built environment discourage walking, but encourage the use of public transit rather than private cars for commuting.
Źródło:
Quaestiones Geographicae; 2020, 39, 4; 87-107
0137-477X
2081-6383
Pojawia się w:
Quaestiones Geographicae
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sensitivity analysis of a fuzzy expert system for modelling dependencies in human operators’ emergency tasks
Autorzy:
Zio, E.
Baraldi, P.
Librizzi, M.
Podofillini, L.
Dang, H. V.
Powiązania:
https://bibliotekanauki.pl/articles/2069589.pdf
Data publikacji:
2007
Wydawca:
Uniwersytet Morski w Gdyni. Polskie Towarzystwo Bezpieczeństwa i Niezawodności
Tematy:
human reliability analysis
fuzzy expert system
sensitivity analysis
Opis:
This paper analyzes the behaviour of a fuzzy expert system for evaluating the dependence among successive operator actions, through a sensitivity analysis on the fuzzy input partitioning and assessment. Preliminary results are presented with respect to a case study concerning two successive tasks of an emergency procedure in a nuclear reactor. Work is in progress to perform a thorough sensitivity analysis to generalize the results obtained.
Źródło:
Journal of Polish Safety and Reliability Association; 2007, 2; 379--389
2084-5316
Pojawia się w:
Journal of Polish Safety and Reliability Association
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sensitivity analysis of performance of Nigerian ports using data envelopment analysis
Autorzy:
Nze, Obiageli N.
Ejem, Ejem Agwu
Powiązania:
https://bibliotekanauki.pl/articles/2141047.pdf
Data publikacji:
2020
Wydawca:
Fundacja Centrum Badań Socjologicznych
Tematy:
Nigerian ports
sensitivity analysis
data envelopment analysis
sustainability
Opis:
With cognizance to some differences among the ports and complexities in productivity measurement, the research tries to identify and evaluate productive issues in terms of technical efficiencies (managerial efficiency) and scale efficiencies (managerial and allocative efficiency) experienced at individual Nigeria ports. It equally provided a technical benchmark for assessing the overall efficiencies of the respective ports in Nigeria during the pre-concessioned and post-concessioned era. The level of inputs required for each DMU to be efficient is given i.e. for DMU 2014 to be efficient input-wise, the number of berth may be reduced by two units as a result of idleness of this two (2) berths, the average turnaround time may be reduced by 3 hours and the berth occupancy may be reduced by 3%. Since a fixed asset such as berth cannot be reduced therefore technically and complimentarily the turnaround time and berth occupancy rate need to be decreased more than 5 hours and 3% respectively by allocating the queue ship at the over-utilized berth to the idle berths which in turn will mitigate underutilization of this berths been required to be reduced or alternatively the port should embrace more cargo handling technology to enhance fast loading and discharging of cargoes thus attracting more vessels to the Port.
Źródło:
Journal of Sustainable Development of Transport and Logistics; 2020, 5, 1; 37-47
2520-2979
Pojawia się w:
Journal of Sustainable Development of Transport and Logistics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Constructing improvement plan for inputs through dialogue with DM about DEA-Efficiency for DMUs
Autorzy:
Uemura, Y.
Powiązania:
https://bibliotekanauki.pl/articles/206812.pdf
Data publikacji:
1999
Wydawca:
Polska Akademia Nauk. Instytut Badań Systemowych PAN
Tematy:
evaluation efficiency
partial improvement plan
sensitivity analysis
Opis:
Evaluation of efficiency of the DMUs (Decision Making Units) in a company is a very important problem. Thus, the studies of evaluation of efficiency are being actively carried out on the basis of the production functions, for example Cobb-Douglas production function and fuzzy loglinear production function (fuzzy Cobb-Douglas model). Recently, DEA (Data Envelopment Analysis) was applied to evaluation of efficiency, in the sense of benchmarking evaluation. After having evaluated DMUs by DEA, we obtain the improvement plan for every input in the inefficient DMUs. Though we many not be able to decrease inputs at one time according to the DEA plan, it is natural to construct some phased improvement plans for decreasing the inputs. First, we propose to support the construction of some phased improvement plans by the sensitivity analysis for the evaluated efficiency by applicatiion of definite limits to the decrease of inputs. Second, we evaluate this method by applying it to the case of bank data.
Źródło:
Control and Cybernetics; 1999, 28, 1; 133-139
0324-8569
Pojawia się w:
Control and Cybernetics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sensitivity analysis of biological tissue freezing process with respect to the radius of spherical cryoprobe
Analiza wrażliwości procesu zamrażania tkanki biologicznej ze względu na promień kriosondy sferycznej
Autorzy:
Majchrzak, E.
Kałuża, G.
Powiązania:
https://bibliotekanauki.pl/articles/280301.pdf
Data publikacji:
2006
Wydawca:
Polskie Towarzystwo Mechaniki Teoretycznej i Stosowanej
Tematy:
freezing process
boundary element method
sensitivity analysis
Opis:
Application of the shape sensitivity analysis to the case of problems of the biological tissue freezing process is discussed. The freezing process described by a strongly non-linear bioheat transfer equation in which an additional term controlling the evolution of latent heat appears. Using the approach called 'the one domain method', one finally obtains a partial differential equation containing the substitute thermal capacity of tissue. The boundary and initial conditions determine the thermal interaction between the tissue and cryoprobe tip. In the paper, we consider a spherical internal cryoprobe. In order to estimate the influence of cryoprobe geometry on the course of the process, the shape sensitivity analysis is applied. In particular, a direct approach is used (explicit differentiation method). The results of numerical modeling (the boundary element method is applied) allow one to formulate essential practical conclusions concerning the course of cryosurgery treatments.
Praca dotyczy zastosowania analizy wrażliwości kształtu w zagadnieniach modelowaniaprocesuzamrażania tkanki biologicznej. Proces ten jest opisany silnie nieliniowym równaniem przepływu biociepła, w którym pojawia się dodatkowy składnik związany z wydzielaniem się utajonego ciepła zamrażania. Formalne przekształcenia wyjściowego równania opisującego proces prowadzi do równania różniczkowego, w którym występuje zastępcza pojemność cieplna tkanki (tzw. metoda jednego obszaru). Odpowiednio przyjęte warunki brzegowe determinują oddziaływania termiczne między tkanką a końcówką kriosondy. W pracy rozważa się sferyczną kriosondę wewnętrzną. VV celu oszacowania wpływu geometrii kriosondy na przebieg procesu zamrażania wykorzystano podejście bezpośrednie analizy wrażliwości kształtu. Wyniki obliczeii numerycznych otrzymane za pomocą metody elementów brzegowych pozwoliły na sformułowanie wniosków przydatnych w praktyce kriochirurgicznej.
Źródło:
Journal of Theoretical and Applied Mechanics; 2006, 44, 2; 381-392
1429-2955
Pojawia się w:
Journal of Theoretical and Applied Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Process of separating acetonitrile and water using LTTMs as entrainer
Autorzy:
Li, Chengshuai
Ma, Wencheng
Powiązania:
https://bibliotekanauki.pl/articles/2081511.pdf
Data publikacji:
2021
Wydawca:
Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
Tematy:
LTTMs
ACN
Simulation
Extraction distillation
Sensitivity analysis
Opis:
New extractive distillation confi gurations, which use low transition temperature mixtures (LTTMs) as entrainers, have attracted widespread attention among scholars due to their green processes. Furthermore, the design and comparison of different processes can promote the application of new solvents in the future. In this study, two extractive distillation processes, the extractive distillation column (ED) and the extraction dividing wall column (EDW), were selected from previous work. The separation process of acetonitrile (ACN)-water ternary mixtures was studied, and GC3:1(choline chloride/glycolic acid mixture (molar mass 1:3)) and EC2:1((choline chloride/ethylene glycol 1:2 molar mass) were used as entrainers. Minimum consumption energy and the purity of ACN and water were set as the goals, and our sensitivity analysis and economic evaluation results showed that both ED and EDW were effective. As a result, LTTMs can be used in extractive distillation for azeotrope separation.
Źródło:
Polish Journal of Chemical Technology; 2021, 23, 4; 1-9
1509-8117
1899-4741
Pojawia się w:
Polish Journal of Chemical Technology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sensitivity analysis as a tool to optimise Human Development Index
Autorzy:
Kuc-Czarnecka, Marta
Powiązania:
https://bibliotekanauki.pl/articles/22446409.pdf
Data publikacji:
2019
Wydawca:
Instytut Badań Gospodarczych
Tematy:
Human Development Index
composite indicators
sensitivity analysis
Opis:
Research background: Composite indicators are commonly used as an approximation tool to measure economic development, the standard of living, competitiveness, fairness, effectiveness, and many others being willingly implemented into many different research disciplines. However, it seems that in most cases, the variable weighting procedure is avoided or erroneous since, in most cases, the so-called ?weights by belief? are applied. As research show, it can be frequently observed that weights do not equal importance in composite indicators. As a result, biased rankings or grouping of objects are obtained. Purpose of the article: The primary purpose of this article is to optimise and improve the Human Development Index, which is the most commonly used composite indicator to rank countries in terms of their socio-economic development. The optimisation will be done by re-scaling the current weights, so they will express the real impact of every single component taken into consideration during HDI?s calculation process. Methods: In order to achieve the purpose mentioned above, the sensitivity analysis tools (mainly the first-order sensitivity index) were used to determine the appropriate weights in the Human Development Index. In the HDI?s resilience evaluation process, the Monte Carlo simulations and full-Bayesian Gaussian processes were applied. Based on the adjusted weights, a new ranking of countries was established and compiled with the initial ranking using, among others, Kendall tau correlation coefficient. Findings & Value added: Based on the data published by UNDP for 2017, it has been shown that the Human Development Index is built incorrectly by putting equal weights for all of its components. The weights proposed by the sensitivity analysis better reflect the actual contribution of individual factors to HDI variability. Re-scaled Human Development Index constructed based on proposed weights allow for better differentiation of countries due to their socio-economic development.
Źródło:
Equilibrium. Quarterly Journal of Economics and Economic Policy; 2019, 14, 3; 425-440
1689-765X
2353-3293
Pojawia się w:
Equilibrium. Quarterly Journal of Economics and Economic Policy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synthesis of a pumping unit with consideration of a flexible member in the system
Autorzy:
Sapietová, A.
Sekerka, M.
Vaško, M.
Sapieta, M.
Powiązania:
https://bibliotekanauki.pl/articles/102969.pdf
Data publikacji:
2016
Wydawca:
Stowarzyszenie Inżynierów i Techników Mechaników Polskich
Tematy:
torque
sensitivity analysis
multibody systems
MSC ADAMS
Opis:
To achieve a correct function and maximal effectiveness of a pumping unit, it is necessary to correctly design the input dynamic parameters. This paper will present sensitivity analysis, which aims to find appropriate input parameters needed to realize the prescribed work tasks from the point of view of consideration of flexible member in the system.
Źródło:
Advances in Science and Technology. Research Journal; 2016, 10, 31; 119-123
2299-8624
Pojawia się w:
Advances in Science and Technology. Research Journal
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Fuzzy global sensitivity analysis of fuzzy net present value
Autorzy:
Sari, I. D.
Kuchta, D.
Powiązania:
https://bibliotekanauki.pl/articles/206340.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Instytut Badań Systemowych PAN
Tematy:
fuzzy sensitivity analysis
fuzzy net present value
Opis:
The cash flows of an investment project are influenced by several factors. All the factors influencing fuzzy net present value of a project should be taken into account, together with their variability, in order to analyze the whole project, and to make the best decisions during the project’s life. In this paper a fuzzy global sensitivity analysis method is proposed for fuzzy net present value to determine the influences of the factors on the worth of an investment project. The results of the proposed method for an application are also interpreted.
Źródło:
Control and Cybernetics; 2012, 41, 2; 481-496
0324-8569
Pojawia się w:
Control and Cybernetics
Dostawca treści:
Biblioteka Nauki
Artykuł
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