- Tytuł:
- "MitoTea": Geranium robertianum L. decoctions decrease blood glucose levels and improve liver mitochondrial oxidative phosphorylation in diabetic Goto-Kakizaki rats
- Autorzy:
-
Ferreira, Fernanda
Peixoto, Francisco
Nunes, Elsa
Sena, Cristina
Seiça, Raquel
Santos, Maria - Powiązania:
- https://bibliotekanauki.pl/articles/1040293.pdf
- Data publikacji:
- 2010
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
oxidative phosphorylation
herbal medicine
Vaccinium myrtillus L.
Goto-Kakizaki (GK) rats
type 2 diabetes mellitus
Geranium robertianum L. - Opis:
- Several chemical compounds found in plant products have proven to possess beneficial properties, being currently pointed out due to their pharmacological potential in type 2 diabetes mellitus complications. In this context, we studied the effect of Geranium robertianum L. (herb Robert) leaf decoctions in Goto-Kakizaki (GK) rats, a model of type 2 diabetes. Our results showed that oral administration of G. robertianum leaf decoctions over a period of four weeks lowered the plasma glucose levels in diabetic rats. Furthermore, the treatment with G. robertianum extracts improved liver mitochondrial respiratory parameters (state 3, state 4 and FCCP-stimulated respiration) and increased oxidative phosphorylation efficiency.
- Źródło:
-
Acta Biochimica Polonica; 2010, 57, 4; 399-402
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł