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Wyszukujesz frazę "cell biology" wg kryterium: Wszystkie pola


Wyświetlanie 1-7 z 7
Tytuł:
Stem cell biology - a never ending quest for understanding.
Autorzy:
Majka, Marcin
Kucia, Magdalena
Ratajczak, Mariusz
Powiązania:
https://bibliotekanauki.pl/articles/1041413.pdf
Data publikacji:
2005
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
stem cells
TCSC
plasticity
Opis:
Stem cells (SC) research is an important part of biotechnology that could lead to the development of new therapeutic strategies. A lot of effort has been put to understand biology of the stem cells and to find genes and subsequently proteins that are responsible for their proliferation, self-renewal and differentiation. Different cytokines and growth factors has been used to expand stem cells, but no combination of these factors was identified that could effectively expand the most primitive stem cells. Recently, however, genes and receptors responsible for SC proliferation and differentiation have been described. Ligands for these receptors or these genes themselves are being already used for ex vivo expansion of stem cells and the first data are very promising. New markers, such as CXCR4 and CD133, have been discovered and shown to be present on surface of hematopoietic stem cells. The same markers were recently also found to be expressed on neuronal-, hepatic- or skeletal muscle-stem cells. By employing these markers several laboratories are trying to isolate stem cells for potential clinical use. New characteristics of stem cells such as transdifferentiation and cell fusion have been described. Our team has identified a population of tissue committed stem cells (TCSC). These cells are present in a bone marrow and in other tissues and they can differentiate into several cell types including cardiac, neural and liver cells.
Źródło:
Acta Biochimica Polonica; 2005, 52, 2; 353-358
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Porous titanium scaffolds with modified surface: in vitro cell biology assessment
Autorzy:
Ścisłowska-Czarnecka, A.
Menaszek, E.
Szaraniec, B.
Chłopek, J.
Kołaczkowska, E.
Powiązania:
https://bibliotekanauki.pl/articles/285246.pdf
Data publikacji:
2009
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
osteoblasts
cytokines
cell adherence
morphology
titanium
hydroxyapatite
bioglass
CaO-SiO2
Opis:
Interaction of host cells with a biomaterial surface is important for biocompatibility and thus is essential for biomedical applications. Therefore investigations are undertaken to scrutinize for an appropriate surface coating with physical and chemical properties minimizing undesirable activation of immunological response. For this the current study was aimed at examining the effects of different surface modifications of titanium by its coating with ceramic materials - hydroxyapatite, bioglass and CaO-SiO2on osteoblast morphology and secretory activity. Titanium is known for its excellent mechanical properties but its surface has low bioactivity. We report that CaO-SiO2coating decreased a number of attached osteoblasts and altered their morphology. Moreover, the ceramic coatings temporarily upregulated release of pro-inflammatory cytokines IL-6 (all of them) and TNF-α (CaO-SiO2). However, overall the levels of the cytokines were low. In contrast, levels of neutrophil-attracting chemokine IL-8 were the highest. IL-8 was produced mostly by cells incubated with hydroxyapatite titanium coating in contrary to those incubated with either bioglass or CaO-SiO2titanium modifications. In conclusion, the titanium coated with ceramics such as hydroxyapatite or bioglass had the best effect on cell adhesion; however, hydroxyapatite might potentially stimulate destructive neutrophils while CaO-SiO2-coating has a negative effect on cell adhesion.
Źródło:
Engineering of Biomaterials; 2009, 12, 88; 5-10
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
International Institute of Molecular and Cell Biology in Warsaw – organizational model for Polish science?
Autorzy:
Witt, Michał
Ziemka, Agnieszka
Powiązania:
https://bibliotekanauki.pl/articles/703240.pdf
Data publikacji:
2007
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
funding
research
institute
organization
projects
Opis:
History, structure, organizational and functional principles of the International Institute of Molecular and Cell Biology in Warsaw are presented. Current developments and the influence of the Institute on Polish scientific milieu, particularly in light of current debate on necessity of reorganization of Polish institutions dealing with research and/or higher education, are being discussed.
Źródło:
Nauka; 2007, 2
1231-8515
Pojawia się w:
Nauka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Biomaterial modifications and cellular behavior
Autorzy:
Staehlke, S.
Rebl, H.
Nebe, J. B.
Powiązania:
https://bibliotekanauki.pl/articles/285488.pdf
Data publikacji:
2017
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
biomaterials
cell biology
medical materials
Źródło:
Engineering of Biomaterials; 2017, 20, no. 143 spec. iss.; 16
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mechanizmy śmierci od komórki do całego organizmu
Mechanisms of cell death from cell to whole organism
Autorzy:
Ciesielska, Sylwia
Powiązania:
https://bibliotekanauki.pl/articles/691931.pdf
Data publikacji:
2019
Wydawca:
Wydawnictwo Uniwersytetu Śląskiego
Tematy:
apoptosis, mathematical models in biology, cell death, homeostasis, predator–prey model
Opis:
In vitro studies are alternative for in vivo studies carried on living organisms. They involve cell populations for both normal and cancer cells. The processes inside cells might be base for defining whole body processes. Starting with fundamental unit of every living organism which is cell, we can distinguish two main types of cell death – apoptosis and necrosis. Human organism is built from 1013–1014 cells of 300 different cell types. During cell division new cells are created and their number is strictly controlled in programmed cell death – apoptosis. Mainly old or damaged cells commit suicide and are removed from organism. This is natural phenomenon and every change in mechanisms of proliferation or apoptosis cause changes and damage in whole organism. Homeostasis in organism depends on correct action of death and survival system. The patterns of equilibrium in nature relies on similar regulation profiles, in which it is similar to death of singular organisms in population or species. It implicates death as natural phenomenon maintaining balance in the world.
Źródło:
Zoophilologica. Polish Journal of Animal Studies; 2019, 5
2719-2687
2451-3849
Pojawia się w:
Zoophilologica. Polish Journal of Animal Studies
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Chemiczna biologia syntetyczna
Chemical synthetic biology
Autorzy:
Huszcza, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1853725.pdf
Data publikacji:
2021
Wydawca:
Polskie Towarzystwo Chemiczne
Tematy:
biologia syntetyczna chemiczna
ksenobiologia
komórka minimalna
chemical synthetic biology
xenobiology
minimal cell
Opis:
Synthetic biology, which in 2020 turned 20 years old, is a very dynamically developing field. Unlike traditional molecular and cellular biology, synthetic biology focuses on the design and construction of parts, devices and systems such as enzymes, genetic circuits, metabolic pathways, etc. that can be modeled and adapted to specific requirements, and assembly into integrated systems for solving specific problems. The basic assumption of synthetic biology is the application of engineering principles such as standardization and modularity. Synthetic biology is traditionally dominated by top-down approaches that incorporate or redesign well-characterized standard biological parts into cellular systems. In synthetic biology research there are also bottom-up approaches aiming to construct cell-like systems starting with molecular building blocks. This complementary approach is called "chemical synthetic biology." In this case the goal is to use unnatural chemicals to reproduce biological behavior. Under the bottom-up approach synthetic biology involves construction of so-called minimal cells or living cells from scratch and creating orthogonal biological systems based on biochemistry not found in nature. Bottom-up approaches complement the study of living cells, facilitate the definition of principles governing biological organization and identify new systems for biotechnological production. Examples of breakthrough achievements in chemical synthetic biology such as peptide nucleic acids and selected developments over the past few years are presented in this review article.
Źródło:
Wiadomości Chemiczne; 2021, 75, 9-10; 1413-1438
0043-5104
2300-0295
Pojawia się w:
Wiadomości Chemiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-7 z 7

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