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Wyświetlanie 1-2 z 2
Tytuł:
Rapidly progressing dementia as a manifestation of the Creutzfeldt-Jakob disease: an analysis of two cases
Autorzy:
Bartosz, Seweryn
Leksa, Natalia
Uberman-Kluz, Dominika
Szymczak, Artur
Biesiadecki, Marek
Galiniak, Sabina
Powiązania:
https://bibliotekanauki.pl/articles/454939.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
14-3-3 protein
brain biopsy
cerebrospinal fluid
Creutzfeldt-Jakob disease
EEG
prion
Opis:
Introduction. Creutzfeldt-Jakob disease (CJD) is a rare and fatal neurodegenerative disease of the central nervous system which is caused by an infectious protein called prion. Multiple forms of CJD have been classified including sporadic (more than 90% cases), familial, iatrogenic and variant type of disease. CJD, especially in its early stages, is a highly challenging illness to diagnose. Aim. Article aims to present cases of Creutzfeldt-Jackob disease with early symptoms of rapidly progressing dementia at the initial stage of CJD. Description of the cases. This paper describes two cases of patients with suspected CJD with a history of rapidly progressive dementia admitted to the Department of Neurology, MSWiA Hospital in Rzeszów. Conclusion. Despite the fact that CJD is an incurable illness and there is no cure guaranteeing recovery, it is important to make the right diagnosis. Assay of 14-3-3 protein in cerebrospinal fluid is a sensitive and specific marker which is helpful in the diagnosis of CJD. The only relevant method of correctly confirming a diagnosis of this disease is by performing a brain biopsy.
Źródło:
European Journal of Clinical and Experimental Medicine; 2019, 1; 89-93
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ocena skuteczności oraz ryzyka powikłań „bezramowej” biopsji stereotaktycznej guzów mózgu opartej na neuronawigacji i badaniu MRI
Effiectiveness and safety of MRI based 'frameless' stereotactic biopsy of brain tumours
Autorzy:
Chodakowski, Paweł
Kapustka, Bartosz
Marcol, Wiesław
Kiwic, Grzegorz
Wysokiński, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1036720.pdf
Data publikacji:
2016
Wydawca:
Śląski Uniwersytet Medyczny w Katowicach
Tematy:
biopsja „bezramowa”
guzy mózgu
biopsja stereotaktyczna
neuronawigacja
'frameless' biopsy
brain tumours
stereotactic biopsy
neuronavigation
Opis:
INTRODUCTION: Stereotactic biopsy is a relatively commonly used tool for brain tumour diagnostics. A frame-based stereotactic biopsy is the standard, but the so-called 'frameless' biopsy, which is done by using a special neuronavigation system, seems to be a safe and convenient alternative. The authors have assessed the safety and effectiveness of an MRI based 'frameless' stereotactic biopsy of brain tumours. MATERIAL AND METHODS: 42 cases of patients, who underwent 'frameless' brain tumour biopsies in 2011–2013, were been retrospectively analysed. The biopsies were done by using BrainLab™ neuronavigation with VarioGuide and biopsy side-cut needles. The operation plan was based on a preoperative MRI head. In every case, at least 3 specimens various trajectories were taken. Pathological analysis was performed in the same place in every case. RESULTS: There were 85.7% cases with an exact histopathological result. 14.3% cases obtained a pathological result, but without exact diagnosis. One patient (2.4%) with astrocytoma WHO III died as a result of a perioperative intraventricular hemorrhage. Other clinically significant perioperative complications occurred in 2 cases (4.8%). The histopathological diagnostics revealed: 12 cases of GBM (28.6%), 8 cases of astrocytoma WHO III (19%), 10 cases of astrocytoma WHO II (23.8%), 1 case of metastasis (2.4%), 1 case of lymphoma (2.4%) as well as 2 other lesions (4.8%). Statistical analysis revealed no significant differences in the patients’ pre- and postoperative state. CONCLUSIONS: The 'frameless' biopsy is an effective and relatively safe way of diagnosing brain tumours. This type of biopsy takes less time to perform. It seems that it can be recommended as a convenient alternative to frame-based biopsy.
Źródło:
Annales Academiae Medicae Silesiensis; 2016, 70; 122-126
1734-025X
Pojawia się w:
Annales Academiae Medicae Silesiensis
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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