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Wyszukujesz frazę "Jiang, S.W." wg kryterium: Autor


Wyświetlanie 1-8 z 8
Tytuł:
MGF360-12L of ASFV-SY18 is an immune-evasion protein that inhibits host type I IFN, NF-κB, and JAK/STAT pathways
Autorzy:
Chen, Q.
Wang, X.X.
Jiang, S.W.
Gao, X.T.
Huang, S.Y.
Liang, Y.
Jia, H.
Zhu, H.F.
Powiązania:
https://bibliotekanauki.pl/articles/16647496.pdf
Data publikacji:
2023
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
African swine fever virus
MGF360-12L
type I IFN
NF-κB
JAK/STAT
Opis:
African swine fever virus (ASFV) causes feverous and hemorrhagic disease of domestic pigs and European wild boars with high mortality, yet no commercial vaccine is currently available. Several ASFV strains with natural deletion or gene-targeted knockout of multiple MGF360 and MGF505 genes are attenuated in vitro and in vivo, and can offer full protection against homologous challenge. However, the mechanisms underlying the protection are not fully understood. This study aims to investigate the effects of MGF360-12L of ASFV-SY18 on the cGAS-STING signaling pathway and explore the potential mechanisms. We identified that ASFV-SY18 MGF360-12L could inhibit cGAS-STING, TBK1, or IRF3-5D-stimulated IFN-β expression and ISRE activation. Specifically, MGF360-12L inhibits both the activation of PRD(III-I) in a dose-dependent manner, and suppresses the exogenous expression of TBK1 and IRF3-5D. MGF360-12L could block NF-κB activation induced by overexpression of cGAS-STING, TBK1, IKKβ. Downstream of the IFN-β signaling, MGF360-12L blocks the ISRE promoter activation by reducing total protein level of IRF9. Moreover, MGF360-12L protein can inhibit IFN-β-mediated antiviral effects. In conclusion, our findings suggest that MGF360-12L is a multifunctional immune-evasion protein that inhibits both the expression and effect of IFN-β, which could partially explain the attenuation of relevant gene-deleted ASFV strains, and shed light on the development of efficient ASFV live attenuated vaccines in the future.
Źródło:
Polish Journal of Veterinary Sciences; 2023, 26, 1; 119-130
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sound Absorption Behavior of Polyurethane Foam Composites with Different Ethylene Propylene Diene Monomer Particles
Autorzy:
Zhu, W.
Chen, S.
Wang, Y.
Zhu, T.
Jiang, Y.
Powiązania:
https://bibliotekanauki.pl/articles/178030.pdf
Data publikacji:
2018
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
polyurethane foam composites
EPDM
Ethylene Propylene Diene Monomer
contents of EPDM
hardness of EPDM
sound absorption coefficient
Opis:
Considering the environmental pollution caused by waste rubber, some measures should be taken to improve the utilization rate of waste rubber. In this study, the effect of Ethylene Propylene Diene Monomer (EPDM) particles in the polyurethane (PU) foams on sound absorption behavior is investigated for improving sound environment within vehicles and reducing the environment pollution. EPDM particles of different contents and hardness are used as fillers for producing foams with different pore morphologies and sound absorption properties. The results show that adding EPDM to foam would produce smaller pores, higher density and bigger air-flow resistivity. Simultaneously, there are better sound absorption properties of the PU foam composites in the medium frequency region, and the better value can be obtained at the lower frequency with the content of EPDM increasing. The hardness of EPDM also shows better influence on sound absorption properties, especially in the medium frequency region. It means the foam pore morphologies have influence on sound absorption properties.
Źródło:
Archives of Acoustics; 2018, 43, 3; 403-411
0137-5075
Pojawia się w:
Archives of Acoustics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Moving-aperture-based three-dimensional micro-measurement system
Autorzy:
Fan, S.
Yu, M.
Jiang, G.
Wang, Y.
Wang, W.
Li, W.
Powiązania:
https://bibliotekanauki.pl/articles/174026.pdf
Data publikacji:
2018
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
optical microscopy
computational photography
three-dimensional micro-measurement
moving aperture
Opis:
To overcome the depth-of-field limitation of an optical microscope image, a three-dimensional measurement method with a superior depth-of-field is proposed. In the proposed method, light-field information of different angles is obtained by moving the aperture and the three-dimensional scene is reconstructed by using a computational reconstruction technology. First, stereo matching of different aperture position images is performed to obtain the multi-aperture imaging deviation. The focal plane moving distance is thereby estimated. Then, the relational expression between the image coordinates and the focal plane moving distance is determined according to the image coordinates. Two dimensional coordinates of the space point are obtained by the expression coefficients. Finally, the depth coordinates are computed, and three-dimensional reconstruction of the spatial points is completed. Experiments of three-dimensional measurements of the calibration board with different angles and circuit boards are conducted. The results show that the maximum error of the distance measurement is controlled into 0.84%, and the maximum angle measurement error is controlled into 4.56%.
Źródło:
Optica Applicata; 2018, 48, 4; 533-547
0078-5466
1899-7015
Pojawia się w:
Optica Applicata
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Unidirectional Torsion Properties of Single Silk Fibre
Właściwości monowłókien jedwabnych przy jednokierunkowym skręcaniu
Autorzy:
Jiang, S.
Cao, G.
Cai, G.
Xu, W.
Li, W.
Wang, X.
Powiązania:
https://bibliotekanauki.pl/articles/232187.pdf
Data publikacji:
2016
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Biopolimerów i Włókien Chemicznych
Tematy:
unidirectional torsion
silk fibre
fracture angle
breaking cycle
SEM
XRD
skręcanie jednokierunkowe
włókno jedwabne
badania
Opis:
The unidirectional torsion properties of silk fibre were investigated on a purpose-built single fibre torsion tester. The torsional fracture angle and the number of cycles of torsion at breaking were recorded, and the effect of the gauge length and pretension together with the torsion speed on the torsion properties of single silk fibre was investigated in detail. Scanning electron microscopy (SEM), X-ray diffraction (XRD) analysis and a tensile tester were used to understand the morphology, structure and tensile properties of silk fibre after torsion deformation. SME photos show that silk fibre exhibits a ribbon-like profile after torsion, and fracture tends to occur at both ends of the silk fibre, where a larger number of twists can be observed. The crystallinity calculated from XRD spectra of silk fibre increases from 26.11% to 34.10% after torsion. The breaking stress and strain decreases slightly with an increase in the gauge length. The breaking cycle increases linearly with an increase in the gauge length, while the actual torsional fracture angle decreases gradually at the same time. The torsional fracture angle together with the breaking cycle decreases gradually as the pretension increases. The fracture angle together with the breaking cycle increases with an increase in the torsion speed. Understanding the unidirectional torsion properties of single silk fibre will benefit its further application in specific areas where the fibre will be subject to frequent torsion and deformation.
Badania przeprowadzono za pomocą specjalnie zbudowanego urządzenia do badania skrętu włókien. Badano kąt przełomu oraz ilość cykli doprowadzających do zerwania. Sprawdzano również wpływ długości próbki oraz wstępnego naprężenia. Oceniono wpływ długości próbki wstępnego naprężenia, szybkości skrętu na właściwości wytrzymałościowe włókien jedwabnych. Stosowano SEM, XRD dla określenia morfologii i struktury włókien. Stwierdzono, że włókna jedwabne po badaniu wykazują formę podobną do taśmy. Na podstawie XRD stwierdzono, że krystaliczność wzrasta od ok. 26% do 34% po skręceniu. Naprężenie zrywające i odkształcenia zmniejszają się lekko przy wzroście długości próbki.
Źródło:
Fibres & Textiles in Eastern Europe; 2016, 3 (117); 26-30
1230-3666
2300-7354
Pojawia się w:
Fibres & Textiles in Eastern Europe
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analysis and Optimization of Micro Speaker-Box Using a Passive Radiator in Portable Device
Autorzy:
Jiang, Y.-W.
Kwon, J.-H.
Kim, H.-K.
Hwang, S.-M.
Powiązania:
https://bibliotekanauki.pl/articles/176530.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
passive radiator
speaker box
SPL improvement
Sound Pressure Level
Opis:
With the rapid development of multimedia devices such as smart phones and tablet PCs, microspeakers have been recently increasingly used for audio equipment. Improving the acoustic performance of a microspeaker is always a main concern, especially in the low frequency range. To avoid sound cancelation, a microspeaker unit is usually inserted into a speaker box. A passive radiator is also used in speaker boxes to improve the sound performance in the loudspeaker system. However, passive radiators have not been applied into microspeaker system. In this study, a speaker box with a passive radiator was analyzed and optimized to achieve a higher Sound Pressure Level (SPL) in a microspeaker system. The Finite Element Method (FEM), two-degree-of-freedom (DOF) vibration theory, and a plane circular piston sound source were used to study the electromagnetic, vibration, and acoustic characteristics, respectively. Optimization was conducted by changing the mass, stiffness, and size of the passive radiator. Based on the optimized parameters, a new sample was manufactured. The experiment results show that the SPL of the optimized speaker box with a passive radiator is improved by 5 dB at 200 Hz compared with the one without a radiator. The analysis results also matched the experiment results.
Źródło:
Archives of Acoustics; 2017, 42, 4; 753-760
0137-5075
Pojawia się w:
Archives of Acoustics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analysis of Crystal Lattice Deformation by Ion Channeling
Autorzy:
Jóźwik, P.
Sathish, N.
Nowicki, L.
Jagielski, J.
Turos, A.
Kovarik, L.
Arey, B.
Shutthanandan, S.
Jiang, W.
Dyczewski, J.
Barcz, A.
Powiązania:
https://bibliotekanauki.pl/articles/1400434.pdf
Data publikacji:
2013-05
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
61.85.+p
68.55.Ln
02.70.Uu
68.37.Og
Opis:
A model of dislocations has been developed for the use in Monte Carlo simulations of ion channeling spectra obtained for defected crystals. High resolution transmission electron microscopy micrographs show that the dominant type of defects in the majority of ion irradiated crystals are dislocations. The RBS/channeling spectrum is then composed of two components: one is due to direct scattering on randomly displaced atoms and the second one is related to beam defocussing on dislocations, which produce predominantly crystal lattice distortions, i.e. bent channels. In order to provide a correct analysis of backscattering spectra for the crystals containing dislocations we have modified the existing Monte Carlo simulation code "McChasy". A new version of the code has been developed by implementing dislocations on the basis of the Peierls-Nabarro model. Parameters of the model have been determined from the high resolution transmission electron microscopy data. The newly developed method has been used to study the Ar-ion bombarded $SrTiO_3$ samples. The best fit to the Rutherford backscattering/channeling spectra has been obtained by optimizing the linear combination of two kinds of defects: displaced atoms and bent channels. The great virtue of the Monte Carlo simulation is that unlike a traditional dechanneling analysis it allows quantitative analysis of crystals containing a mixture of different types of defects.
Źródło:
Acta Physica Polonica A; 2013, 123, 5; 828-830
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Isolation and sequence analysis of the complete VP2 gene of canine parvovirus from Chinese domestic pets and determination of the pathogenesis of these circulating strains in beagles
Autorzy:
Chen, M.R.
Guo, X.Y.
Wang, Z.Y.
Jiang, Y.T.
Yuan, W.F.
Xin, T.
Hou, S.H.
Song, T.Q.
Lin, W.D.
Zhu, H.F.
Jia, H.
Powiązania:
https://bibliotekanauki.pl/articles/2087542.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
canine parvovirus
molecular epidemiology
phylogenetic analysis
pathogenesis
Źródło:
Polish Journal of Veterinary Sciences; 2019, 2; 287-296
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-8 z 8

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