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Wyszukujesz frazę "Farhat, M.B." wg kryterium: Autor


Wyświetlanie 1-2 z 2
Tytuł:
Phytochemical characterisation and bioactive properties of Solanum sodomaeum L. fruits at two stages of maturation
Autorzy:
Ouerghemmi, I.
Farhat, M.B.
Harbeoui, H.
Hammami, M.
Hamdaoui, G.
Marzouk, B.
Tounsi, M.S.
Powiązania:
https://bibliotekanauki.pl/articles/71442.pdf
Data publikacji:
2018
Wydawca:
Instytut Włókien Naturalnych i Roślin Zielarskich
Tematy:
phytochemistry
bioactive property
antibacterial property
antioxidant activity
essential oil
fatty acid
Solanum sodomaeum
fruit
maturation
Opis:
Introduction: Solanum sodomaeum L. has been observed to have several medicinal properties, in particular, in the treatment of several types of human skin cancer. Objective: The influence of the maturation stage of S. sodomaeum fruits on the total lipid contents, fatty acid profiles, essential oil yields and compositions, as well as the antibacterial and antioxidant activities of the essential oils, was investigated. Methods: The fatty acid and essential oil constituents were identified using gas chromatography (GC) and GC–mass spectrometry (GC–MS). The antioxidant properties of essential oil and vegetal oil were assessed using 1,1-diphenyl-2-picryl-hydrazyl (DPPH) scavenging and reducing power assays. The antibacterial ac-tivity of essential oil was tested using the disc diffusion assay for resistance in human pathogenic bacteria. Results: Mature fruits showed higher total lipid content (17%) and were characterised by polyunsaturated fatty acids (53.87%), represented mainly by linoleic acid (53.11%). Similar yields of essential oils were detected for immature (0.43%) and mature (0.45%) fruits. Tetrahydronaphthalene (41.79%) was detected as the major essential oil component at the immature stage versus dihydrocoumarin pentane (18.27%), hexadecanoic acid (17.43%) and 2-undecanone (13.20%) in mature fruits. The DPPH test showed that essential oils had better antioxidant properties; however, the vegetal oils showed better performance in the reducing power assay. Moreover, the essential oil of S. sodomaeum mature fruits was active against bacterial strains. Conclusions: S. sodomaeum fruits could be a valuable source of natural antioxidants and antibacterial agents.
Źródło:
Herba Polonica; 2018, 64, 3
0018-0599
Pojawia się w:
Herba Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
TEMPERATURE DEPENDENT SOLUBILITY STUDIES OF BRIGATINIB IN SOME PURE SOLVENTS USEFUL IN DOSAGE FORM DEVELOPMENT
Autorzy:
MOHAMMAD, MUQTADER
ANWER, Md Khalid
FATIMA, FARHAT
ALSHAHRANI, SAAD M.
ALSHETAILI, ABDULLAH S.
ALALAIWE, AHMED
ALSULAYS, BADER B.
SHAKEEL, FAIYAZ
Powiązania:
https://bibliotekanauki.pl/articles/895362.pdf
Data publikacji:
2019-04-30
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
Lung cancer
curve fitting
Thermodynamic dissolution
mole fraction solubility
Apelblat model
Opis:
In the current study, thermodynamic dissolution of brigatinib in six pure solvents namely, water, ethanol, isopropyl myristate (IPM), poly(ethylene glycol)-400 (PEG-400), dichloromethane (DCM) and ethyl acetate (EA) at (298.2-323.2K) temperature and 0.1 MPa atm. pressure were carried out using flask shaking technique.The mole-fraction solubility of brigatinib was obtainedgreatest in IPM (6.09 x 10-2) and least in water (3.12 x 10-6) at298.2 K.Experimentally obtained solubilities values of brigatinib were regressed using adapted Apelblat equation with root mean square deviations in the range of 1.91 to 4.67 in all solvents and similar trends were observed with increased the temperature. The solubility data generated in this investigation could be helpful for investigator for analysis/dosage form development of brigatinib.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 2; 225-232
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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