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Wyświetlanie 1-10 z 10
Tytuł:
New functionality of RNAComposer: an application to shape the axis of miR160 precursor structure
Autorzy:
Antczak, Maciej
Popenda, Mariusz
Zok, Tomasz
Sarzynska, Joanna
Ratajczak, Tomasz
Tomczyk, Katarzyna
Adamiak, Ryszard
Szachniuk, Marta
Powiązania:
https://bibliotekanauki.pl/articles/1038732.pdf
Data publikacji:
2016
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
RNA 3D structure prediction
RNAComposer
plant miRNA precursor
Opis:
RNAComposer is a fully automated, web-interfaced system for RNA 3D structure prediction, freely available at http://rnacomposer.cs.put.poznan.pl/ and http://rnacomposer.ibch.poznan.pl/. Its main components are: manually curated database of RNA 3D structure elements, highly efficient computational engine and user-friendly web application. In this paper, we demonstrate how the latest additions to the system allow the user to significantly affect the process of 3D model composition on several computational levels. Although in general our method is based on the knowledge of secondary structure topology, currently the RNAComposer offers a choice of six incorporated programs for secondary structure prediction. It also allows to apply a conditional search in the database of 3D structure elements and introduce user-provided elements into the final 3D model. This new functionality contributes to a significant improvement of the predicted 3D model reliability and it facilitates a better model adjustment to the experimental data. This is exemplified based on the RNAComposer application for modelling of the 3D structures of precursors of the miR160 family members.
Źródło:
Acta Biochimica Polonica; 2016, 63, 4; 737-744
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Changes in habitat conditions in a Late Glacial fluviogenic lake in response to climatic fluctuations (Warta River valley, central Poland)
Autorzy:
Forysiak, Jacek
Okupny, Daniel
Obremska, Milena
Antczak-Orlewska, Olga
Płóciennik, Mateusz
Pawłowski, Dominik
Baradyn, Daria
Kotrys, Bartosz
Luoto, Tomi P.
Nevalainen, Liisa
Borówka, Ryszard K.
Powiązania:
https://bibliotekanauki.pl/articles/13955341.pdf
Data publikacji:
2023
Wydawca:
Państwowy Instytut Geologiczny – Państwowy Instytut Badawczy
Tematy:
multi-proxy analysis
Late Weichselian
denudation processes
palaeoclimate
central European river
Opis:
The Warta River valley was greatly influenced by the ice sheet of the Last Glacial Maximum (LGM). A small peatland located in the Warta drainage system is here used as a palaeoarchive of climatic and habitat changes during the Late Glacial (Weichselian). The Ługi sediment profile was investigated using multi-proxy (pollen, Chironomidae, Cladocera and geochemistry) analyses that recorded changes in a fluviogenic sedimentary depression. After the Poznań Phase (LGM), Ługi functioned as an oxbow lake that was cut off from the active river channel as a result of fluvial erosion. Since that time, the Warta River has flowed only along the section now occupied by the Jeziorsko Reservoir. Sedimentation of lacustrine deposits started at the beginning of the Late Glacial. Summer temperature reconstructions indicate cool Oldest and Younger Dryas, but no clear cooling in the Older Dryas. During the Younger Dryas the palaeolake was completely occupied by a peatland (fen), which periodically dried out during the Holocene. Investigation of this site has tracked the reaction of the habitat to climatic, hydrological and geomorphological changes throughout the Late Weichselian.
Źródło:
Geological Quarterly; 2023, 67, 1; art. no. 1
1641-7291
Pojawia się w:
Geological Quarterly
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
1000 Liver Transplantations at the Department of General, Transplant and Liver Surgery, Medical University of Warsaw - Analysis of Indications and Results
Autorzy:
Krawczyk, Marek
Grąt, Michał
Barski, Krzysztof
Ligocka, Joanna
Antczak, Arkadiusz
Kornasiewicz, Oskar
Skalski, Michał
Patkowski, Waldemar
Nyckowski, Paweł
Zieniewicz, Krzysztof
Grzelak, Ireneusz
Pawlak, Jacek
Alsharabi, Abdulsalam
Wróblewski, Tadeusz
Paluszkiewicz, Rafał
Najnigier, Bogusław
Dudek, Krzysztof
Remiszewski, Piotr
Smoter, Piotr
Grodzicki, Mariusz
Korba, Michał
Kotulski, Marcin
Cieślak, Bartosz
Kalinowski, Piotr
Gierej, Piotr
Frączek, Mariusz
Rdzanek, Łukasz
Stankiewicz, Rafał
Kobryń, Konrad
Nazarewski, Łukasz
Leonowicz, Dorota
Urban-Lechowicz, Magdalena
Skwarek, Anna
Giercuszkiewicz, Dorota
Paczkowska, Agata
Piwowarska, Jolanta
Gelo, Remigiusz
Andruszkiewicz, Paweł
Brudkowska, Anna
Andrzejewska, Renata
Niewiński, Grzegorz
Kilińska, Beata
Zarzycka, Aleksandra
Nowak, Robert
Kosiński, Cezary
Korta, Teresa
Ołdakowska-Jedynak, Urszula
Sańko-Resmer, Joanna
Foroncewicz, Bartosz
Ziółkowski, Jacek
Mucha, Krzysztof
Senatorski, Grzegorz
Pączek, Leszek
Habior, Andrzej
Lechowicz, Robert
Polański, Sławomir
Leowska, Elżbieta
Pacho, Ryszard
Andrzejewska, Małgorzata
Rowiński, Olgierd
Kozieł, Sławomir
Żurakowski, Jerzy
Ziarkiewicz-Wróblewska, Bogna
Górnicka, Barbara
Hevelke, Piotr
Michałowicz, Bogdan
Karwowski, Andrzej
Szczerbań, Jerzy
Powiązania:
https://bibliotekanauki.pl/articles/1396689.pdf
Data publikacji:
2012-06-01
Wydawca:
Index Copernicus International
Tematy:
liver transplantation
indications
results
mortality
Opis:
The aim of the study was to analyze indications and results of the first one thousand liver transplantations at Chair and Clinic of General, Transplantation and Liver Surgery, Medical University of Warsaw.Material and methods. Data from 1000 transplantations (944 patients) performed at Chair and Clinic of General, Transplantation and Liver Surgery between 1994 and 2011 were analyzed retrospectively. These included 943 first transplantations and 55 retransplantations and 2 re-retransplantations. Frequency of particular indications for first transplantation and retransplantations was established. Perioperative mortality was defined as death within 30 days after the transplantation. Kaplan-Meier survival analysis was used to estimate 5-year patient and graft survival.Results. The most common indications for first transplantation included: liver failure caused by hepatitis C infection (27.8%) and hepatitis B infection (18%) and alcoholic liver disease (17.7%). Early (< 6 months) and late (> 6 months) retransplantations were dominated by hepatic artery thrombosis (54.3%) and recurrence of the underlying disease (45%). Perioperative mortality rate was 8.9% for first transplantations and 34.5% for retransplantations. Five-year patient and graft survival rate was 74.3% and 71%, respectively, after first transplantations and 54.7% and 52.9%, respectively, after retransplantations.Conclusions. Development of liver transplantation program provided more than 1000 transplantations and excellent long-term results. Liver failure caused by hepatitis C and B infections remains the most common cause of liver transplantation and structure of other indications is consistent with European data.
Źródło:
Polish Journal of Surgery; 2012, 84, 6; 304-312
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-10 z 10

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