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Wyszukujesz frazę "18FDG" wg kryterium: Wszystkie pola


Wyświetlanie 1-6 z 6
Tytuł:
Enriched water-H2 18 O purification to be used in routine 18FDG production
Autorzy:
Al Rayyes, A. H.
Powiązania:
https://bibliotekanauki.pl/articles/148761.pdf
Data publikacji:
2010
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
H2 18 O
radiopharmaceuticals
purification
18FDG
Opis:
18O-water obtained from an 2-deoxy-2-[18F]-fluoro-D-glucose (18FDG, Synthera) synthesis unit is used for purification. The purification process consists of ultraviolet (UV) irradiation followed by a distillation in a preevacuated system. After purification, the loss of enriched water was about only 5 per cent. Organic compounds, radioisotopes, trace metals and gases are eliminated efficiently. Results show that there is no significant difference in the production yield of 2-deoxy-2-[18F]-fluoro-D-glucose ([18F]FDG) whether using purified enriched water by the proposed method of purification or using the new enriched water. This method offers the necessary precaution from contamination by tritium during the purification process. The obtained 18FDG or Na-18F using the purified 18O-water is of tritium free.
Źródło:
Nukleonika; 2010, 55, 3; 401-405
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Radiation doses to technologists working with 18F-FDG in a PET center with high patient capacity
Autorzy:
Demir, M.
Demir, B.
Yaşar, D.
Sayman, H. B.
Halac, M.
Ahmed, A. S.
Özcan, K.
Uslu, I.
Powiązania:
https://bibliotekanauki.pl/articles/148501.pdf
Data publikacji:
2010
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
whole-body dose
finger doses
personnel dosimetry
18F-FDG
PET-CT
Opis:
The increasing numbers of PET studies for routine diagnosis creates a real hazard to radiation workers. The aim of this study is to estimate the annual whole-body and finger radiation dose to technologists working with 18F-FDG in a PET center with high patient potential. In our PET center, the number of PET imaging has increased almost to 5000 studies per year. Our standard dose for tumor imaging is 518 MBq of 18F-FDG. Five technologists performing all steps of 18F-FDG imaging (5 patients per technologist in a day) were officially involved round the week for handling and injecting 18F-FDG to patients. Whole-body and finger dose measurements with TLDs were performed for two different time periods: i) before shielding precautions during the first 6 months (without a shielding for sterile syringe and without a lead container for shielded syringe) and ii) after shielding precautions during the next 6 months (with a shielding for sterile syringe and with a lead container for shielded syringe). The average annual whole-body radiation dose for one technologist before shielding precautions was 7.82 mSv and after shielding precautions was 5.76 mSv. On the other hand, while the average annual finger radiation doses for one technologist before shielding precautions were 210.36 and 293.72 mSv for the left and right hand, after shielding precautions were they 158.16 and 217.58 mSv for the left and right hand, respectively. According to our results, if one technologist performs the whole-body PET imaging of 5 patients per day, the annual radiation dose to this technologist will not exceed the recommended limits by ICRP.
Źródło:
Nukleonika; 2010, 55, 1; 107-112
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Rola badania PET/CT w diagnostyce otępień
The role of PET/CT in the diagnostics of dementia
Autorzy:
Mączewska, Joanna
Królicki, Leszek
Powiązania:
https://bibliotekanauki.pl/articles/1030208.pdf
Data publikacji:
2016
Wydawca:
Medical Communications
Tematy:
18F-FDG
PET/CT
choroba Alzheimera
neuroobrazowanie
otępienie
otępienie z ciałami Lewy’ego
Opis:
A growing number of people with dementia translates into the necessity to use modern imaging methods. Function tests assessing glucose metabolism in the brain, such as 18F-FDG PET/CT, are conducted in the case of clinical doubts and facilitate the differential diagnostics of dementia. In the case of the Alzheimer’s disease, glucose metabolism disorders become visible, above all, in the area of both the parietotemporal areas, posterior parts of the callosal gyrus, the precuneus as well as medial temporal lobe. In the case of dementia with the Lewy bodies, glucose metabolism disorders relate to the occipital lobes and both the parietotemporal areas. In the case of frontotemporal dementia, lesions are observed, above all, in the frontal lobes and poles of the anterior temporal lobes. On the other hand, in the case of vasogenic dementia, there are numerous, spread deficits visible in collecting a marker within the brain – both the cortex and the subcortical nuclei. Characteristic glucose metabolism disorders are present also in the case of other, less common neurodegenerative diseases, such as corticobasal degeneration and the atrophy of the posterior part of the brain. In the case of corticobasal degeneration, one can observe a decreased collection of 18F-FDG within the sensory-motor cortex, in the subcortical nuclei and the thalamus on the side with the disease, while in the case of atrophy of the posterior part of the brain – within both the parieto-occipital areas. Besides glucose metabolism, it is possible to assess the presence of β amyloid in the brain. It is deemed that a negative result of PET/CT for β amyloid enables to exclude the Alzheimer’s disease as being the cause of dementia. The utilisation of non-invasive PET/CT makes it possible to early diagnose dementia and determine the prognosis.
Rosnąca liczba starszych osób z otępieniem przekłada się na konieczność stosowania nowoczesnych metod obrazowania. Badania czynnościowe oceniające metabolizm glukozy w mózgowiu, takie jak 18F-FDG PET/CT, są przeprowadzane w razie wątpliwości klinicznych i ułatwiają diagnostykę różnicową chorób otępiennych. W przypadku choroby Alzheimera zaburzenia metabolizmu glukozy uwidaczniają się przede wszystkim w obrębie obu okolic skroniowo-ciemieniowych, tylnych części zakrętów obręczy, przedklinka, a także części przyśrodkowych płatów skroniowych. W otępieniu z ciałami Lewy’ego zaburzenia metabolizmu glukozowego dotyczą płatów potylicznych i obu okolic skroniowo-ciemieniowych. W zwyrodnieniu czołowo-skroniowym zmiany obserwuje się przede wszystkim w płatach czołowych i biegunach przednich płatów skroniowych. Z kolei w otępieniu naczyniopochodnym widoczne są liczne, rozsiane ubytki gromadzenia znacznika w obrębie mózgowia – zarówno kory, jak i jąder podkorowych. Charakterystyczne zaburzenia metabolizmu glukozy są obecne również w innych, rzadszych chorobach neurodegeneracyjnych, takich jak zwyrodnienie korowo-podstawne i zanik tylnej części mózgu. W zwyrodnieniu korowo-podstawnym obserwuje się zmniejszone gromadzenie 18F-FDG w obrębie kory czucioworuchowej, w jądrach podkorowych oraz we wzgórzu po zajętej stronie, natomiast w zaniku tylnej części mózgu – w obrębie obu okolic ciemieniowo-potylicznych. Oprócz metabolizmu glukozy można oceniać obecność amyloidu β w mózgowiu. Uważa się, że negatywny wynik badania PET/CT pod kątem amyloidu β pozwala na wykluczenie choroby Alzheimera jako przyczyny zespołu otępiennego. Zastosowanie nieinwazyjnych badań PET/CT umożliwia wczesne postawienie diagnozy zespołu otępiennego i ustalenie rokowania.
Źródło:
Aktualności Neurologiczne; 2016, 16, 3; 146-151
1641-9227
2451-0696
Pojawia się w:
Aktualności Neurologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of primary musculocutaneous Hodgkin’s lymphoma with the aid of 18F FDG PET/CT – a rare entity
Autorzy:
Kakkar, Lavish
Singh, Man Mohan
Deswal, Satyawati
Thakur, Priyamedha Bose
Powiązania:
https://bibliotekanauki.pl/articles/40614539.pdf
Data publikacji:
2024-06-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
cutaneous lymphoma
muscular lymphoma
musculocutaneous Hodgkin’s lymphoma
refractory
Opis:
Introduction and aim. Primary musculocutaneous lymphoma is extremely rare and associated with poor prognosis. Here, we present a case of refractory primary muscular lymphoma with overlying cutaneous involvement with the aid of 18F-Fluorodeoxyglucose positron emission tomography/computed tomography (18F FDG PET/CT) for staging and treatment. Description of the case. We present the case of a 52-year-old man presented with musculocutaneous Hodgkin’s lymphoma having swelling and discolored areas over the left leg and right arm associated with itchiness. Upon examination, there was scaling, erythema over the body with Gottron’s papules on knuckles and heliotrope rash. Skin and muscle biopsy were suggestive of Hodgkin’s lymphoma. This patient was had primary musculocutaneous lymphoma. His diagnosis was delayed. PET/CT was performed for staging and response to treatment, which was suggestive of refractory disease. Conclusion. PET/CT plays a vital role in diagnosis, staging, response to therapy and helps in optimized treatment for these specific patients.
Źródło:
European Journal of Clinical and Experimental Medicine; 2024, 22, 2; 452-456
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Using PET/CT imaging performance to qualify 18F-Fluorodeoxy- glucose (FDG) uptake in common carp (Cyprinus carpio)
Autorzy:
Zaheri- Abdehvand, Sabouran
Csipkés, Roland
Forgács, Attila
Trencsényi, György
Garai, Ildikó
Komlósi, István
Powiązania:
https://bibliotekanauki.pl/articles/972575.pdf
Data publikacji:
2016
Wydawca:
Instytut Medycyny Wsi
Tematy:
glucose metabolism
FDG PET
CT
Opis:
Introduction. Positron Emission Tomography (PET) is a non-invasive diagnostic tool that provides tomographic images and measures quantitative parameters of cell viability and metabolic activity of tissues. The most important used tracer in PET is an 18-F-Fluorodeoxy-glucose (FDG), the glucose molecule of which is labeled with a radiotracer and allows measurement and mapping of tissue glucose uptake. There are many studies in PET/CT which rely on some mammalian species, and recently on fish. Objective. The aim of this survey by using FDG-PET/CT are to optimize and determine FDG uptake in fish, in this case, common carp (Cyprinus carpio) using three treatments: Basic fish meal, Vita Pulvis and Probiotics s with two replications were used. Sphere Volume of interest (VOI) were drawn hand for the all organs, and standard uptake value (SUV) means were calculated. Results. The SUV mean for glucose uptake in the liver and gastrointestinal tract of fish were more similar to those of humans than rats or mice. SUV mean in fish fed by Probiotics ss in the major organ were less than those fed by Vita Pulvis and basic fish meal. The results present the opportunity to focus on studies of metabolism and screening for the effects of nutrients on body development.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2016, 10, 1; 60-62
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Production of [18F] fluoride with a high-current two layer spherical gold target
Autorzy:
Mirzaii, M.
Afarideh, H.
Hadji-Saeid, S.
Aslani, G.
Ensaf, M.
Powiązania:
https://bibliotekanauki.pl/articles/147973.pdf
Data publikacji:
2004
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
water target
[18F] fluorine
FDG
PET
high current
Opis:
A new automated target for high yield production of aqueous [18F] fluoride at high beam currents has been constructed for a cyclotron at NRCAM in Karaj (Cyclone 30). It consists of one small golden sphere inside another target chamber, mounted into a special holder, which provides rapid cooling by water flow around and inside the sphere. The target is irradiated with 28 MeV protons. The incident energy on the target chamber is 18 MeV. This target is operated without external overpressure and has been tested for beam currents up to 60 ěA. The measured target yield is 80% of the theoretically calculated yield of 18F, which is used for the synthesis of [18F] 2-fluoro-2-deoxy-D-glucose.
Źródło:
Nukleonika; 2004, 49, 1; 23-27
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-6 z 6

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