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Tytuł:
Physical activity in type 2 diabetes mellitus: a review
Autorzy:
Burooj, Ahmed
Powiązania:
https://bibliotekanauki.pl/articles/33777868.pdf
Data publikacji:
2024-04-10
Wydawca:
Gdański Uniwersytet Medyczny
Tematy:
T2DM
Exercise
Diabetes
Diabetes Mellitus
Physical Activity
Opis:
Introduction This literature review explores the role of physical activity (PA) in managing and preventing type 2 diabetes mellitus (T2DM), synthesizing the latest guidelines for all T2DM patients. Following PRISMA guidelines, it identifies specific areas for further research. Material and Methods Indexing services (PubMed and Scopus) were used to identify relevant studies, emphasizing original research, review articles, and updated institutional guidelines spanning 2017-2023. The following keywords were used: diabetes, physical activity, type 2 diabetes mellitus, PA, and exercise. Proposal and opinion articles, non-English papers (or those lacking full-text translation), studies involving non-human subjects, pediatric populations or with skewed gender distribution were excluded. Results PA improves quality of life, BMI, glycemic control and well-being. Effects vary by activity domain, such as work or leisure time. Recommendations suggest 60 daily minutes of exercise for children, 150 weekly minutes of moderate intensity exercise for adults, and screening for adverse events. A “sit-less” approach is proposed for those unable to maintain regular activity, with glycemic monitoring for those with variability. Conclusions PA is crucial in T2DM management. Conflicting findings regarding glycemic control warrant further investigation to ascertain causes, whether related to bias or other factors.
Źródło:
European Journal of Translational and Clinical Medicine; 2024, 7, 1; 97-105
2657-3148
2657-3156
Pojawia się w:
European Journal of Translational and Clinical Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Age-dependent systemic DNA damage in early Type 2 Diabetes mellitus
Autorzy:
Rogulj, Dinko
El Aklouk, Ismail
Konjevoda, Paško
Ljubić, Spomenka
Pibernik Okanović, Mirjana
Barbir, Ante
Luburić, Marijana
Radman, Maja
Budinski, Ninoslav
Vučić Lovrenčić, Marijana
Powiązania:
https://bibliotekanauki.pl/articles/1038637.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
metabolic syndrome
type 2 diabetes mellitus
DNA damage
urinary 8-OHdG
Opis:
Oxidative stress, capable of eliciting damage to various biomolecules including DNA, is a recognized component of diabetes mellitus and its complications. Metabolic syndrome (MetS) is associated with the development of type 2 diabetes mellitus (T2DM), as well as other unfavorable outcomes. The aim of this study was to elucidate the role of oxidative stress in the development of T2DM, by investigating association of oxidative DNA damage with metabolic parameters in subjects with MetS and early T2DM. Selected anthropometric and biochemical parameters of MetS, inflammation and oxidative DNA damage: body mass index (BMI), fatty liver index (FLI), waist circumference (WC), total cholesterol, HDL and LDL-cholesterol, gamma-glutamyl transpeptidase (GGT), uric acid, C-reactive protein (CRP), total leukocyte/neutrophil count, and urinary 8-hidroxy-deoxyguanosine (u-8-OHdG) were assessed in male subjects with MetS and both younger (≤55 years) and older (>55 years) subjects with T2DM of short duration without complications. BMI, FLI, WC, total and LDL-cholesterol and uric acid were higher, while the u-8-OHdG was lower in MetS group, when compared to older T2DM subjects. None of these parameters were different neither between MetS and younger T2DM, nor between two sub-groups of subjects with T2DM. Values of CRP, HDL-cholesterol, triglycerides, GGT, leukocytes and neutrophils were not different between all examined groups of subjects. Higher 8-OHdG in older subjects with T2DM suggests that both aging process and diabetes could contribute to the development of DNA damage. Oxidative DNA damage cannot serve as an universal early marker of T2DM.
Źródło:
Acta Biochimica Polonica; 2017, 64, 2; 233-238
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Selenium and copper in type 2 diabetes mellitus - more doubt than certainty
Autorzy:
Zabłocka-Słowińska, K.
Grajeta, H.
Powiązania:
https://bibliotekanauki.pl/articles/960069.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
Opis:
Type 2 diabetes mellitus (T2DM) is one of the most common chronic illnesses nearly all over the world and the prevalence of this disorder is still growing. Particularly in industrialized countries, it has become the most serious global medical and public problem, next to cancer and cardiovascular diseases. Despite intensive developments in the research on T2DM pathogenesis, the impact of nutritional factors, and particularly the effect of trace elements, on the development of this disease has not been identified completely, although relationships between some elements, e.g. Zn, Fe, Cr, and T2DM have been described in detail. Critical review of the literature indicates that the majority of inconsistencies appear in studies on Cu and Se: on the one hand, these minerals have strong antioxidant properties and even insulin-mimetic action; on the other hand, an increased risk of T2DM positively correlates with a high dietary intake of Se and Cu or supplementation with these elements. High content of these minerals in diets observed in selected countries and/or increasing popularity of dietary supplementation with Se or Cu, especially among chronically ill patients including ones with T2DM, can cause distortions in the molecular pathways of glucose metabolism. The influence of these minerals on inducing diabetic complications is even more vague and depends on several factors, e.g. the body status of these and other trace elements, the type of complications and the duration of T2DM. The relationship between T2DM and the status of Se and Cu is complex and bidirectional, thus a well-balanced diet providing these trace elements in proper amounts, according to the demand of an organism, may be one of the strategies in reducing the risk of T2DM and its complications.
Źródło:
Journal of Elementology; 2017, 22, 1
1644-2296
Pojawia się w:
Journal of Elementology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Knowledge on risk factors for type 2 diabetes mellitus among secondary school students
Autorzy:
Gora, A.
Szczepanska, E.
Janion, K.
Powiązania:
https://bibliotekanauki.pl/articles/2087307.pdf
Data publikacji:
2020
Wydawca:
Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
Tematy:
knowledge
high school students
type 2 diabetes mellitus
risk factors
Opis:
Background. Diabetes is a set of metabolic diseases characterized by hyperglycemia caused by improper action and/ or secretion of insulin. Currently, diabetes is becoming a serious challenge in modern medicine, this disease affects 425 million people, and the forecasts indicate that by 2045 the number of cases will increase to 629 million. Objective. The aim of the study was to evaluate the knowledge about risk factors for type 2 diabetes among secondary school students in the Silesian Province in Poland and to determine whether there are differences between the level of knowledge between girls and boys and between first-, second- and third-grade students. Material and methods. The survey was conducted among 650 high school students. The research tool was the author's questionnaire. The obtained results were developed using Microsoft Excel 2010 and Statistica 13.3 (TIBCO Inc.). Results. The definitions of type 2 diabetes were known to 63.9%. 91.8% of high school students indicated excessive body mass as a risk factor for morbidity, while 18.8% of people indicated the appropriate type of obesity increasing the risk of type 2 diabetes. Most of the students considered abnormal eating habits as an important factor increasing the occurrence of the disease (92.4%). The most numerous group of high school students were people with average level of knowledge (89.6%). Conclusions. The knowledge of high school students about risk factors for type 2 diabetes was varied. The most numerous group were high school students characterised by the average level of knowledge. There were no statistically significant differences between the proportion of correctly provided responses by women and men. There were statistically significant differences between the proportion of correctly provided responses by first-, second- and third-graders. Our research shows that educational activities should be undertaken, especially about modifiable risk factors for type 2 diabetes.
Źródło:
Roczniki Państwowego Zakładu Higieny; 2020, 71, 4; 431-443
0035-7715
Pojawia się w:
Roczniki Państwowego Zakładu Higieny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Stigma and its relationship with life satisfaction in patients with type 2 diabetes mellitus
Autorzy:
Turen, Sevda
Yurtsever, Melike
Powiązania:
https://bibliotekanauki.pl/articles/40418503.pdf
Data publikacji:
2024-03-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
life satisfaction
stigma
type 2 diabetes mellitus
Opis:
Introduction and aim. This study aims to determine the level of stigma in patients with type 2 diabetes mellitus (T2DM) and evaluate its relationship with their life satisfaction. Material and methods. This is a descriptive and cross-sectional study conducted in a single tertiary care center. Two hundred and ten patients ≥18 years old diagnosed with T2DM were included in this study. The relationship between the “Type 2 diabetes stigma assessment scale” and the “Satisfaction with life scale” was assessed using Pearson correlation analysis. Results. The average age of the participants was 54.85±15.81 years. The majority of patients reported adherence to diabetes treatment and having comorbidities. Stigma levels were higher in patients ≤65 years, those with less than a high school education, and those receiving insulin or oral anti-diabetic treatment, but lower with a T2DM diagnosis duration of ≤ 5 years (p<0.05). Life satisfaction was influenced by age, education status, economic status, adherence to treatment, dietary compliance, and the presence of comorbidities. A moderately negative relationship between stigma level and life satisfaction was identified. Conclusion. The study’s results indicate that an increase in stigma level is associated with a decrease in life satisfaction in patients with type 2 diabetes mellitus.
Źródło:
European Journal of Clinical and Experimental Medicine; 2024, 22, 1; 128-133
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Prevalence of depression in Indian patients with type 2 diabetes mellitus and/or hypertension: DEPTH Study
Autorzy:
Lalwani, Raj Kumar
Shah, Jayesh Dashrathlal
Chatterjea, Tapas
Nadakuduru, Papa Rao
Erande, Suhas
Powiązania:
https://bibliotekanauki.pl/articles/454720.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
comorbidity
diabetes
depression
hypertension prevalence
type 2 diabetes mellitus
Opis:
ABSTRACT Introduction. Depression, a common psychiatric mood disorder, is a leading cause of disability and a significant contributor to the overall global burden of disease. Aim. To determine the prevalence of depression in patients with controlled and uncontrolled type-2 diabetes mellitus (T2DM) and/or hypertension (HTN) in India. The association of depression with socio-demographic profile and clinical risk factors was also assessed. Material and methods. In this cross-sectional epidemiological study, T2DM and/or HTN patients attending outpatient department at tertiary care hospitals and private clinics across 54 cities in India were enrolled. The primary outcome measure was to determine the prevalence of depression in T2DM, HTN and T2DM + HTN patients. Association of depression with patients’ demography, socio-economic status, anxiety, and clinically diagnosed insomnia were also investigated. Results. Of 1829 patients, the prevalence of depression in T2DM, HTN and T2DM+HTN cases were found to be 51.03%, 46.94% and 48.64%, respectively. A higher proportion of patients with uncontrolled T2DM and HTN reported depression (T2DM: 77.64% vs. 22.36%; HTN: 72.49% vs. 27.51%). There was a significant association between anxiety and severity of depression across all indications (p<0.0001). Depression was significantly associated with complications in T2DM (p=0.0001) and comorbidities in T2DM + HTN (p=0.0023) cases. Conclusion. Depression is highly prevalent and has a direct significant association with various socio-demographic variables and anxiety in Indian patients with T2DM and/or HTN.
Źródło:
European Journal of Clinical and Experimental Medicine; 2019, 4; 315-325
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Comparative analysis of socioeconomic, behavioral and biological factors between healthy patients and patients with newly diagnosed diabetes in the Lubuskie Voivodeship
Autorzy:
Bonikowska, I.
Jasik-Pyzdrowska, J.
Szwamel, K.
Powiązania:
https://bibliotekanauki.pl/articles/2087637.pdf
Data publikacji:
2020
Wydawca:
Uniwersytet Opolski. Instytut Nauk o Zdrowiu
Tematy:
patients
type 2 diabetes mellitus
prediabetic state
Opis:
Background: The most effective way to prevent an increasing diabetic population lies in early detection of risk factors and diagnosis of carbohydrate metabolism disorders. Aim of the study: The study aimed at determining socio-economic variables, lifestyle behaviours and biological factors differentiating patients with newly diagnosed diabetes from diabetes-free individuals. Material and methods: Assessment of diabetic vs. non-diabetic individuals was performed according to the American criteria issued by the Commission on Social Determinants of Health as well as the FINDRISC form, which helps identify patients who are at risk of developing type 2 diabetes on the basis of multi-factorial determinants of its development. The research was conducted in 2018 among 1167 primary health care patients from Lubuskie Voivodeship using a diagnostic survey method which interviewed the respondents according to the FINDRISC standard questionnaire. Results: The group of healthy patients was similar to the group of patients with newly diagnosed diabetes with respect to variables such as age (p=0.713), sex (p=1), place of residence (p=1), level of education (p=0.076), professional activity (p=0.758), BMI (p=0.133), waist measurement (p=0.665), frequency of fruit and vegetables intake (p=0.572), frequency of taking hypotensive medications (p=0.176), frequency of diabetes occurrence in the family history (p=0.227) and physical activity (p=0.321). Conclusions: Early detection of carbohydrate metabolism disorders, with the use of standardised tools that assess diabetes development, appears to be essential in the prevention of this disorder. Therefore, there is a strong need to create a tool adjusted to socio-demographic factors such as geographical location, economic conditions and lifestyle. Additionally, active and massive screening for carbohydrate metabolism disorders in patients with a low risk of diabetes seems to be crucial in its prevention.
Źródło:
Medical Science Pulse; 2020, 14, 3; 55-63
2544-1558
2544-1620
Pojawia się w:
Medical Science Pulse
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Homocysteine as a non-classical risk factor for atherosclerosis in relation to pharmacotherapy of type 2 diabetes mellitus
Autorzy:
Borowska, Magdalena
Dworacka, Marzena
Winiarska, Hanna
Krzyżagórska, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1038542.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
homocysteine
atherosclerosis
type 2 diabetes
Opis:
Aims. The aim of our study was to evaluate which of the pharmacotherapeutic methods that are frequently used to treat type 2 diabetes is associated with the most beneficial profile in relation to pro-atherogenic homocysteine levels. Patients and Methods. We measured the serum homocysteine level in 182 patients with type 2 diabetes treated with metformin (89), treated with insulin in combination with metformin (31), receiving sulfonylureas (31) and treated conventionally with insulin (31). The total homocysteine levels in the serum were assayed. To exclude the influence of selected metabolic and anthropometric factors on the differences between the examined groups, multivariate analysis of covariance was used (ANCOVA). In this analysis, serum homocysteine concentration was the dependent variable, while diabetes duration, waist circumference, HbA1c, 1,5-anhydro-D-glucitol, fasting glycaemia and peptide C were used as covariates. Results. The serum homocysteine levels in patients treated with insulin in monotherapy were significantly higher than what was observed in the metformin treated subjects and in the patients receiving insulin combined with metformin. The analysis of covariance also confirmed that the differences between the therapeutic groups were affected by waist circumference and the C-peptide levels. Conclusion. We conclude that conventional insulin therapy may have a negative effect on pro-atherogenic homocysteine levels in patients with type 2 diabetes. This study revealed that pro-atherogenic homocysteine levels may not only be modified by pharmacotherapy of type 2 diabetes, but also by beta cell secretory function and abdominal obesity.
Źródło:
Acta Biochimica Polonica; 2017, 64, 4; 603-607
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The utility of nerve conduction studies in patients with diabetic polyneuropathy
Autorzy:
Banach, Marta
Powiązania:
https://bibliotekanauki.pl/articles/552713.pdf
Data publikacji:
2015
Wydawca:
Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:
type 2 diabetes mellitus
nerve conduction studies
diabetic polyneuropathy
Źródło:
Family Medicine & Primary Care Review; 2015, 3; 171-174
1734-3402
Pojawia się w:
Family Medicine & Primary Care Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The relationship between anthropometry and ankle-brachial index with blood glucose level in patients with type 2 diabetes mellitus at the Community Health Center in Medan, Indonesia
Autorzy:
Rina, Amelia
Burhan, Burhan Burhan
Aznan, Lelo
Powiązania:
https://bibliotekanauki.pl/articles/552972.pdf
Data publikacji:
2018
Wydawca:
Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:
anthropometry
ankle-brachial index
blood glucose
type 2 diabetes mellitus.
Źródło:
Family Medicine & Primary Care Review; 2018, 4; 307-312
1734-3402
Pojawia się w:
Family Medicine & Primary Care Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The psychological and emotional state of patients with type 2 diabetes mellitus on the background of excessive body weight
Autorzy:
Velichko, V. I.
Nikitina, V. I.
Said, E. V.
Amirova, A. Yu.
Powiązania:
https://bibliotekanauki.pl/articles/765447.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Mikołaja Kopernika w Toruniu. Wydział Nauk o Ziemi i Gospodarki Przestrzennej. Katedra Kultury Fizycznej
Tematy:
diabetes mellitus type 2, overweight, depressive disorders, anxiety disorders, psychoemotional status
Opis:
In the work, we studied the parameters of the psychological and emotional state of patients with type 2 diabetes mellitus on the background of excessive body weight. Psychological and emotional state studies were conducted using the Patient Health Questionnaire-PHQ-9, questionnaire the hospital scale of anxiety and depression (HADS). A comparison of the frequency of occurrence of anxiety-depressive disorders and the study of the degree of their severity in the patients under study. The study revealed that negative changes in the indicators of psychological and emotional state in patients with type 2 diabetes are six times more likely than in healthy people.
Źródło:
Journal of Education, Health and Sport; 2017, 7, 3
2391-8306
Pojawia się w:
Journal of Education, Health and Sport
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Association between UBE2E2 variant rs7612463 and type 2 diabetes mellitus in a Chinese Han Population
Autorzy:
Kazakova, Elena
Wu, Yanhui
Zhou, Zhongyu
Chen, Meijun
Wang, Tongtong
Tong, Huixin
Zhuang, Tianwei
Sun, Lulu
Qiao, Hong
Powiązania:
https://bibliotekanauki.pl/articles/1039098.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Type 2 diabetes mellitus
UBE2E2
rs7612463
Single nucleotide polymorphism
SNPscan
Opis:
UBE2E2 encodes ubiquitin-conjugating enzyme E2E2, which plays an important role in the synthesis and secretion of insulin. Two previous studies indicated that SNPs in UBE2E2 were associated with risk for type 2 diabetes mellitus (T2DM) in the Japanese and Korean populations, respectively. We examined the association of one SNP in this gene, rs7612463, with the risk of T2DM in 1957 Han participants in northeastern China, using an SNPscanTM Kit. rs7612463 genotype was significantly associated with risk for T2DM under various genetic models, including an additive model (P = 0.004), a dominant model (P = 0.024), and a recessive model (P = 0.008). The AA genotype was associated with a significantly decreased risk for T2DM (P = 0.004, OR = 0.513, 95% CI = 0.325-0.810) after adjustment for age, gender, and BMI. The heterozygous genotype, AC, was associated with increased risk for total cholesterol (mmol l-1; P = 0.031) and triglycerides (mmol l-1; P = 0.039) in control individuals. Our results show that rs7612463 is associated with T2DM, with homozygotes of the AA genotype at decreased risk for T2DM in the Chinese population. Additionally, heterozygotes may have decreased risk of T2DM due to insulin resistance.
Źródło:
Acta Biochimica Polonica; 2015, 62, 2; 241-245
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Selected Physical Fitness Parameters in Individuals with Type 2 Diabetes Mellitus and Apparently Healthy Controls: A Comparative Cross-Sectional Study
Autorzy:
Ogunlana, Michael O.
Lateef, Ramon O.
Oyewole, Olufemi O.
Raimi, Taiwo H.
Alimi, Talayo J.
Adesina, Olubiyi
Odole, Adesola C.
Faniyi, Oluwatimilehin
Ayodeji, Ayomikun F.
Adebimpe, Busayo D.
Afolabi, Wasiu
Adepoju, Modinant O.
Ogunsola, Bose F.
Powiązania:
https://bibliotekanauki.pl/articles/39824761.pdf
Data publikacji:
2022
Wydawca:
Politechnika Opolska. Wydział Wychowania Fizycznego i Fizjoterapii
Tematy:
Fitness
Evaluation
Cardio-respiratory
Physical
Diabetes
Opis:
Objective: The study aimed to compare the physical fitness of subjects with type 2 diabetes mellitus (ST2DM) and apparently healthy non-diabetic controls (NDC). Methods: Thirty-two ST2DMs and 32 NDCs were recruited for a comparative cross-sectional study. Flexibility, balance, power, and strength were assessed using sit-up and sit and reach (SR), one leg stand, horizontal jump (HJ), and hand grip tests, respectively. Cardiovascular endurance was assessed using Vo2max estimated with a 6-minute walk test. Also, body composition was estimated using body mass index (BMI), waist circumference (WC), hip circumference (HC), waist-hip ratio (WHR), and percent body mass. Data were analyzed using descriptive and inferential statistics. The alpha level was set at p < 0.05. Results: Static balance was significantly higher in the NDCs (11.1 ± 12.6 vs 5.5 ± 5.0 sec; p = 0.047) than in the ST2DMs. Hand (34.6 ± 19.9 vs 23.6 ± 12.7 kg; p = 0.001) and leg (122.4 ± 42.8 vs 26.5 ± 43.9 cm; 0.001) strength/power were significantly higher in the NDC group compared with the ST2DM. The SR test, a measure of flexibility, was significantly higher in the NDC (SDM = 12.2 ± 19.8cm, NDC = 35.3 ± 8.8cm, p = 0.001). BMI (28.7 ± 4.3 vs 26.4 ± 41kgm-2; p = 0.048), WC (104.2 ± 8.0 vs 94.2 ± 8.7cm; p = 0.001) and WHR (1.0 ± 0.6 vs 0.9 ± 0.7; p = 0.001) were significantly higher in the ST2DM than in the NDC. There was no significant difference in the estimated VO2max between the subject group and the control group. Conclusion: Balance, flexibility, and strength were significantly lower, while measures of adiposity are significantly higher in subjects with type 2 diabetes mellitus compared with non-diabetic controls.
Źródło:
Journal of Physical Education & Health - Social Perspective; 2022, 11, 19; 13-22
2084-7971
Pojawia się w:
Journal of Physical Education & Health - Social Perspective
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Lack of association between UBE2E2 gene polymorphism (rs7612463) and type 2 diabetes mellitus in a Saudi population
Autorzy:
Alharbi, Khalid
Khan, Imran
Al-Sheikh, Yazeed
Alharbi, Fawiziah
Alharbi, Fahad
Al-Nbaheen, May
Powiązania:
https://bibliotekanauki.pl/articles/1039212.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
T2DM
UBE2E2
PCR-RFLP
Saudi population
Opis:
The ubiquitin-conjugating enzyme E2E 2 (UBE2E2) gene plays an important role in insulin synthesis and secretion under conditions in which stress to the endoplasmic reticulum is increased in β-cells. In this case-control study, we have selected rs7612462 polymorphism within UBE2E2 gene to identify in a Saudi population the type 2 diabetes mellitus (T2DM) subjects. In total, 376 subjects with T2DM and 380 controls were enrolled in this study. We have collected 5 mL of peripheral blood from each participant for biochemical and molecular analyses. PCR-RFLP was used to generate genotypes at rs7612462 in all of the study subjects. Clinical data and anthropometric measurements of the patients were significantly different from those of the controls (p<0.05). All of the subjects used in this study were non-obese (25
Źródło:
Acta Biochimica Polonica; 2014, 61, 4; 769-772
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wsparcie społeczne a kontrola poziomu cukru we krwi w cukrzycy typu 2
Social support and glycemic control in type 2 diabetes mellitus
Autorzy:
Kocemba, Iwona
Powiązania:
https://bibliotekanauki.pl/articles/2139601.pdf
Data publikacji:
2007
Wydawca:
Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Tematy:
diabetes mellitus
social support
HbA1c
Opis:
Diabetes is an incurable disease. Recently researchers are focusing more often on the role of the social support in diabetes treatment. It seams that support from family and friends plays a big role in the results of the disease treatment. Lack of such support may decrease patients’ treatment motivations. The aim of this study was to estimate the relationship between social support and metabolic control. The group which was examined consisted of 35 people with type 2 diabetes not treated with insulin and 31 who were on insulin. The Social Support Inventory by Saranson and glycosylated hemoglobin (HbA1c) for glycemic control were used in this study. The research indicates that poorer metabolic control was correlated with the lack of social support.
Źródło:
Acta Universitatis Lodziensis. Folia Psychologica; 2007, 11; 59-65
2353-4842
Pojawia się w:
Acta Universitatis Lodziensis. Folia Psychologica
Dostawca treści:
Biblioteka Nauki
Artykuł
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