Rezonans magnetyczny i spektroskopowa ocena metabolitow tkanki mozgowej w przebiegu kryptokokozy OUN

Cryptococcus neoformans is the causative agent of cryptococcosis and cryptococcal meningitis, which are serious pathological conditions affecting up to 10% of patients with AIDS. In this paper we present results magnetic resonance imaging and spectroscopic metabolites (1H MR) in brain cryptococcosis. In 1HMR spectroscopy we tind decreased metabolic ratios to nonsaturated water (H2O) signal N-acetylaspartate (NA/H20, creatine (Cr/H20), choline (Cho/H20). We show increased mioinositol to H2O ratio. Spectroscopy results suggest about massive neuronal injury and accompanying gliosis in brain cryptococcosis.