A study into the relationship between anxiety-depression and self-esteem disorder in patients with multiple sclerosis at the Rabat Ibn Sina Hospital, Morocco

Multiple Sclerosis (MS) is a chronic inflammatory disease affecting the central nervous system through the destruction of sheaths (myelin), disseminated in space and time. The aim of our work is to study the neurocognitive concept and mood disorders in patients with MS. The study includes in this study 75 cases of MS, collected at the Neurology (B) and Neurogenetics Department of Rabat Ibn Sina Hospital. The study was performed on MS patients using different scales that included: a self-questionnaire (socio-demographic, clinical), Hospital Anxiety and Depression scale (HADS), Rosenberg's Self-Esteem scale (RSE) and Expanded Disability Status Scale (EDSS). The mean age for the onset of the disease was 30-years, with a sex ratio of 3.4. The main clinical signs are: 69.33% and 70.67% of patients had respectively anxious and depressive disorder, which was associated with low self-esteem in 89% of them. The distribution according to the evolutionary forms of MS is 65% Relapsing Remitting (RR), 29% secondary progressive (SP) and 5% Primary Progressive (PP). As for the assessment of disability using EDSS, we note an average 4.07±1.829. That results of our study concord with other studies on the same age category. It confirms the predominance of women. They are followed by the appearance of psychological disorders such as depression anxiety and cognitive disorders. Remitting MS is the most common when compared to other forms. The anxiety and depression score was strongly correlated with the degree of self-esteem and disability.