Biocomatibility study of BOC polymer mesh enriched with HAp and TCP covered by PCL fibres

The study was conducted in order to determine the biocomatibility of polimer mesh based on BOC and enriched with HAp or TCP coverd by PCL sub-micrometric fibres. Human osteoblast cell line NHOst was cultured in standard conditions on disk-shaped polymer samples. Interactions between materials and cells were examined through microscopic observation of cells' adhesion and morphology, and tests of viability/proliferation and cytotoxicity. The study proved the biocompatibility of all examined materials, though the surface of TCP enriched polymer didn't promote the adhesion of cells.