Doświadczalna toksoplazmoza kotów

Forteen cats were used for the experiments, including 6 infected intraperitoneally, 4-perorally, 2-intraconjunctivally, 1-intratracheally, with one animal serving as a control. An acute course of the disease was found in two cats, subacute in three, and chronic in the remaining animals. One cat, infected perorally was found to be free of toxoplasmosis. Clinical picture of the disease, hematologic, electrophoretic, serologic studies and anatomo-pathologic findings are presented. The results obtained prompt the following conclusions: (1) The course of experimental toxoplasmosis in cats is likely to depend on the age, invasion route, and the material used for infecting purposes. (2) The observed clinical symptoms and anatomo-pathologic alterations do not seem to be typical of this disease. (3) Hematologic and electrophoretic studies are not contributory to the diagnosis. (4) The Sabin-Feldman's dye test apparently reflects the course of the disease, whereas the complement fixation test, for unknown reasons, fails, being negative in majority of cases with toxoplasmosis confirmed by other methods.