Wpływ intensywności inwazji włośni Trichinella na proces fagocytozy Candida albicans przez makrofagi myszy

Experiments were carried out on male Balb/c mice, weighing 20 g. The Candida cells (Candida albicans L 45) were killed by heat-treatment and obsonized with mouse serum. Macrophages were obtained from the peritoneal cavity. Phagocytosis was executed by incubation 0,2 ml of suspension of macrophages with 0,2 ml of Candida suspension. Microscopic slides with cell smear were preparated. The phagocytic index and the percentage of phagocytizing macrophages were calculeted. It was found that infection with Trichinella spiralis or Trichinella pseudospiralis caused a significant reduction in the phagocytic capacity and the percentage of phagocytizing macrophages. This reduction depended on the intensity of invasion.