The natural acetylenic products containing at least one a carbon-carbon triple
bond, are important class of compounds widely distributed in the environment.
Development of spectroscopic techniques and methods for the isolation of metabolites
allowed the extraction of natural acetylenic compounds. The most of these substances
have been obtained from marine organisms, such as: cyanobacteria, algae
and sponges. The next source of metabolites are herbal plants, which were used in
the Chinese traditional medicine. A many of them show interesting biological activity.
The first isolated natural compound possessing an acetylenic unit was dehydromatricaria
ester, which was obtained from rhizome European goldenrod (Solidago
virgaurea). To present day have been found and researched more than 2000 natural
acetylenic metabolites.
Due to the chemical structure, natural acetylenic compounds were divided into
six groups: peptides, aromatic compounds, enediyne antibiotics, sterols, carotenoids,
and poliacetylenic compounds .
This article focuses natural acetylenic substances, which exhibit interesting biological
properties, particularly anticancer ones. The review presents many of such
metabolites, including fatty alcohols, ketones, acids, ethers, and carotenoids.
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