Applications of Raman scattering in biomedicine, telecommunication and thermometry

The paper presents a brief review of methodologies and applications based on the spontaneous and stimulated Raman scattering in telecommunication, thermography and biomedicine. We present the results on cancer biodiagnostics by Raman imaging based on the spontaneous Raman scattering. We showed that combined Raman imaging based on spontaneous Raman scattering and AFM are capable of monitoring biomechanics of tumor vascularity, which is markedly heterogeneous with densely vascularized areas supplying oxygen and nutrients to rapidly growing parts of the tumor. The experimental evidence provides greater understanding of the biomechanics of cancer cell and tissue deformability and its interactions with the extracellular matrix environments offering enormous potential for significant new developments in cancer diagnostics, therapy and drug treatment.