The evaluation of the in-vitro antimicrobial activity of Alangium salvifolium (Linn)

Finding healing power in plants is an ancient idea, and people of all continents and civilization have been using plants in one form or the other for poultices or as decoctions. Alangium salvifolium (Linn), family Alangeaceae, is a tree that grows in the wild throughout India. The plant has been used in the Indian traditional system of medicine for skin diseases (e.g. leucoderma), articular diseases, and anti-inflammation, anti-poisonous, anti-pyretic, and anti-emetic requirements. However, no scientific evidence is available regarding its antimicrobial activity. An investigation of Alangium salvifolium as an antimicrobial activity agent is the objective of our present study. The ATCC culture used in this study was collected from department of Microbiology, G.M.C., Bhopal (M.P.). Shade dried crude powder (200 grams) of seed of Alangium salvifolium was separately extracted with methanol in a soxhelt apparatus. The Antimicrobial activities were then studied by applying the Disc–Diffusion method. Our results indicate that the observed antimicrobial activity of the fraction appears to be due to unknown secondary metabolites in it. H.P.L.C. (high performance liquid chromatography) and chemical studies may, thus be useful in analyzing the presence of unknown secondary metabolites in the fractions.