Solvent-free synthesis, antimicrobial and insect antifeedant potentials of some 4(4-chloro-1-naphthyl)-5,6-dihydro-6-(substituted phenyl)-4H-1,3-oxazine-2-amines

More than 85% yields of thirteen 4-(4-chloro-1-naphthyl)-5,6-dihydro-6-(substituted phenyl)-4H-1,3-oxazine-2-amines weer synthesised by SiO2-H3PO4 catalyzed solvent-free cyclization of substituted styryl4-chloro-1-naphthyl ketones and urea under microwave irradiation. The synthesized oxazine amines have been characterized by analytical and spectroscopic techniques. The antimicrobial activities of these 4-(4-chloro-1-naphthyl)-5,6-dihydro-6-(substituted phenyl)-4H-1,3-oxazine-2-amines have been appraised by means of Bauer-Kirby technique. The insect antifeedant activities of these oxazine-2-amines were assessed by Dethler’s technique using 4th instar larvae Achoea janata L.