Fungi of the Aspergillus genus are widely distributed in nature, including more than
300 species, but only a few of them are pathogenic for humans and animals. Aspergillus can
grows on organic substrates in soil, on plants. Spores are constantly present in air, and with it
food, household items, outer integument and mucous person causing the disease to cause
aspergillosis. When aspergillosis usually affects the respiratory system, in some cases, skin,
kidneys, brain, eyes. Invasive pulmonary aspergillosis is associated with high mortality. In
recent years, the number of cases has increased. At risk are people with immune deficiencies.
Crucial in the fight against this disease promptly started playing antifungal therapy and early
diagnosis. When selecting tests are important technical and economic indicators of the complexity or simplicity the study, its reproducibility, the applicability of automated
screening and cost analysis. In the present article we have analyzed and compared different
methods for aspergillosis diagnostics. Biotechnological approaches for development of
allergy/aspergillosis diagnostic preparations also have been discussed.
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