Multiple sclerosis is a chronic inflammatory disease which, due to the destruction of the fibres of the central nervous
system in the process of demyelination, leads to numerous neurological symptoms and progressive disability. The disease
is autoimmune, which means that myelin is destroyed by the patient’s own cells, caused by improper functionong and
regulation of the immune system. Multiple sclerosis affects more and more people and is therefore a significant clinical
problem which, to a large Entent, affects women, especially in childbearing age This presents a big challenge for carrying out
pregnancy while continuing the therapy, ensuring the safety of the foetus and simultaneously achieving the best possible
therapeutic effect. The decision whether the therapy should be continued or whether it should be eliminatedis usually
made according to assessment of the possible gains and losse. Despite the lack of clear indications, there are many studies
proving the relative safety of the use of individual but not all the drugs during pregnancy. Pregnancy, however, has a fairly
good impact on the development of multiple sclerosis, and that safety considerations, especially those concerning the
growing foetus, force a decision to change or completely suspend the therapy. In-depth research on the already available
and emerging therapeutic pathways in multiple sclerosis bring hope for increasingly better results in the future in the
treatment of pregnant patients with multiple sclerosis.
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